Diabetes Mellitus As A Group Of Metabolic Diseases Essay

Type II Diabetes, also known as diabetes mellitus, is also called non-insulin-dependent diabetes or aadult onset diabetes. It is a medical disorder that, due to a number of factors codependent with the modern world, is characterized by higher than normal blood glucose levels that play havoc with insulin deficiency and resistance. Insulin resistance means that cells do not respond appropriately when there is free insulin in the blood system. Essentially, they body is reacting to an improper balance of sugars and insulin. Because obesity is often present, research suggests that even thought the mechanisms controling glucose and insulin are unclear, the adopose tissue likely

Diabetes is a disease where the body is unable to produce or use insulin effectively. Insulin is needed for proper storage and use of carbohydrates. Without it, blood sugar levels can become too high or too low, resulting in a diabetic emergency. It affects about 7.8% of the population. The incidence of diabetes is known to increase with age. It’s the leading cause of end-stage renal disease in the US, and is the primary cause of blindness and foot and leg amputation. It is known to cause neuropathy in up to 70% of diabetic patients. Individuals with diabetes are twice as likely to develop cardiovascular disease. There are two types of diabetes: Type 1 and Type 2.

Diabetes is a growing concern and health challenge for the American people (b). Diabetes is a condition in which the body cannot react to insulin appropriately or either cannot produce insulin efficiently (w). “Without a properly functioning insulin signaling system, blood glucose levels become elevated and other metabolic abnormalities occur, leading to the development of serious, disabling complications” (w). There are numerous forms of diabetes amongst the nation, however, there are three main forms of diabetes. Most people have heard of type one diabetes, type two diabetes, and gestational diabetes because they are common. Type two diabetes deals with a resistance to insulin, while

     Diabetes mellitus is a group of metabolic disorders characterized by inadequate insulin secretion by the pancreas or cellular destruction leading to an insulin deficiency. Depending on the cause of the insulin shortage, diabetes can be subcategorized into type I and type II. Type I diabetes (T1DM) is usually mediated by the destruction of b-cells in the pancreas resulting in decreased insulin production and secretion. Type II diabetes (T2DM) is the failure of these b-cells to secrete adequate amounts of insulin to compensate for insulin resistance and increased gluconeogenesis combined with an overall resistance to the insulin action (8., 1997). T2DM accounts

Annotated Bibliography Entry: Lamster, Ira B.. Diabetes Mellitus and Oral Health : An Interprofessional Approach (1). Somerset, US: Wiley-Blackwell, 2014. ProQuest ebrary. Web.

Insulin resistance is the first physiological change occurring in type two diabetes. In these type two diabetic patients, insulin is unable to move glucose into liver, kidney and muscle cells although insulin is able to attach properly to the cell surface receptors. In order to rectify this, most patients with type two diabetes start secreting normal to very high levels of insulin, which can initially overcome this resistance. After a while, the pancreas cannot keep up with this high insulin production and the cells become resistant to glucose intake. Persistent hyperglycemia or high blood glucose levels are not desirable since this causes damage to the beta cells of the pancreas that produces the insulin hormone. This damage to beta cells further hampers insulin synthesis and patients at this stage are categorized as full-blown diabetic. Such patients consistently show a hyperglycemia state even after hours of fasting ( Hinkle & Cheever,

Diabetes Mellitus (DM) or Type 2 Diabetes is seen as a metabolic disease that is categorized by abnormally high blood glucose or hyperglycemia. Diabetes Mellitus is also formerly known as noninsulin-dependent diabetes mellitus and is the most common form of diabetes that is seen. Insulin is a hormone that is supplied to the body that allows us to efficiently use glucose as fuel. When carbohydrates are broken down into sugars in the stomach glucose enters the blood circulation simulating the pancreas to release insulin in an appropriate amount to become used for energy. With diabetes mellitus the body does not properly make use of the insulin supplied for the body. This causes the pancreas to produced an extra amount if insulin which the body cannot keep up with, causing an imbalance to the blood glucose levels (American Diabetes Association, 2015). In the united states diabetes affects almost 29.1 million people, while the another 86 million people have pre-diabetes but do not know. It is also known as the 7th leading cause of death in the country in the recent years (MedicineNet.com, 2016). For a patient suffering from a chronic form of diabetes mellitus understanding how these mechanisms lead to the condition can be used as preventative measures. Potential consequences as well as the causes and clinical manifestations will ensure a better knowledge on the issue to monitor the condition.

Metabolic disorders-Noninsulin dependent diabetes mellitus, hyperlipidaemia (cholesterol and triglyceride), gallstones, hyperuricaemia and gout are common among obese.

Diabetes is a very common chronic medial disorder and expected to be a big medical challenge of the twenty first century (Clark, 2004). It is a condition, in which the glucose level in the blood becomes so high that the body is unable to utilize it properly. This long-term condition results when the pancreas of the victim is either not able to produce enough insulin (sometimes even cannot produce any insulin) or the insulin produced cannot work properly. Diabetes is divided into two main types: Type 1 and Type 2. Type 1, also known as insulin dependent diabetes milletus (Masharani, 2008) cannot be prevent while Type 2 can be prevented but if the patient is at pre-diabetes stage.

Type 2 Diabetes Mellitus (T2DM) is the most common form of diabetes in the U.S., and it is a severe disease with numerous life-threatening consequences. T2DM occurs when insulin, which is a hormone released by the pancreas for sugar metabolism, becomes low or cannot be utilized by cells. In the normal condition, insulin circulates in the bloodstream and enables to convert starch, sugar, and all polysaccharides complex into glucose, which cells use for energy; however, in T2DM, there is continuously too much glucose in the bloodstream. When cells don’t interact appropriately with insulin, blood sugar increases, and this phenomenon is called insulin resistance that leads to many health problems,

Diabetes mellitus (DM) is a condition in the body that is related to a faulty metabolism. It means that the body’s metabolism is not functioning properly, which leads to adverse effects in the health. The food we ingest, gets broken down into blood sugar (glucose), which is what fuels our body in the form of energy. This converted glucose needs to enter our cells so that it can be used for energy and growth. And in order for the glucose to enter our cells, there needs to be insulin present, which the beta cells of the pancreas is responsible for producing. This hormone is responsible for maintaining glucose level in the blood. It allows the body cells to use glucose as a main

It is one of the two categories of diabetes: Type 1 is the insulin-reliant while Type 2 is the non-insulin-reliant. The aspects of Type 2 diabetes are insulin-inability where the cells and tissues lack response to insulin. Another aspect is the loss of pancreatic Beta-cell function that damages the creation of insulin and secretion. The Beta-cell function is important because it is balanced by glucagon-like peptide-1 (GLP-1) and oxidative stress that cuts down glucagon secretion, attending to gastric emptying, and weight gain. Type 2 diabetes weakens the activity of GLP-1, causing Hyperglycemia. Hyperglycemia advances to clinical issues such as cardiovascular diseases, kidney deterioration, and neuropathy. There is also the aftermath of lipid metabolism abnormality, leading to lipid toxicity further complicating the individual’s

Diabetes mellitus (DM), also known as diabetes, is a disease that directly affects the way the endocrine system produces or uses insulin throughout the body. When a person has diabetes, the pancreas does not produce a sufficient amount of insulin or the body becomes resistant to the insulin produced; these factors depend on which type of diabetes the patient is diagnosed with (Hart & Loeffler, 2015). Insulin is a vital component in the body used to convert glucose (sugar) in to energy. If the body cannot make or use insulin properly, patients exhibit hyperglycemia, which is an excessive amount of glucose in the blood. If diabetes is left untreated or not managed properly, the disease can cause severe and permanent damage to vital organs, diabetic

Diabetes mellitus (or diabetes) is a threatening disease which occurs as a result of loss of uptake of glucose by cell thus increasing its concentration in the blood(Walker and Colledge 2013). Glucose, normally referred to as blood sugar is mainly present in blood and acts to provide energy to the body. It can be thought of a syndrome of hyperglycemic condition where disorders in metabolism occur(Tierney, Saint et al. 2002). It can be termed as metabolic sickness portrayed by hyperglycemia which result due to deformities in insulin discharge, its activity or both of these(Alberti and Zimmet 1998, American Diabetes 2010). The chronic state of disease is that in which hyperglycemia can lead to disorders affecting organs such as kidneys, heart ,eyes and blood vessels etc.(American Diabetes 2010).Diabetes occurs usually when the release of

Diabetes is considered a metabolic disorder. Glucose is obtained from the food we ingest and normally insulin is released as the glucose levels rise. Insulin is produced in the pancreas by cells called Beta cells. Diabetes results from an imbalance of the hormone insulin. When Beta Cells fail to produce insulin the levels of glucose in the blood rise as the kidney is not able to filtrate the high amounts of glucose in the blood. Another cause of diabetes can be insulin resistance. Insulin resistance occurs when the body is not able to utilize the available insulin. Insulin is in charge of maintaining the proper levels of glucose in the plasma. Insulin levels are raised when the levels of glucose in the blood are high. Insulin activates the absorption of glucose by the cells that need it. The excess glucose is filtered out of the body as urine. This is the cause for constant urination in diabetics. As the body tries to get rid of the excess glucose polyuria occurs. Glucose is of great importance as it provides energy to cells such as those in the muscles and brain to properly function. In diabetics even though there is high levels of glucose the organs are not able to utilize it because insulin is not sufficient and the absorption of glucose by the cells does not occur. Symptoms may not be evident but the may increase as the disease progresses. There are three major types of diabetes, type 1, type 2, and gestational diabetes which will be fully explained