Introduction Diabetes Mellitus, also known commonly as diabetes, is a chronic condition in which the body doesn’t produce or misuses insulin in the body. There are different classifications of diabetes: Type 1, Type 2, and gestational diabetes. Type 1 is when the body does not produce any insulin. It is usually diagnosed in children and young adults. Type 2 is when the body doesn’t use insulin properly and can develop in anyone and seen at any age. Both types require strict management which…

Type 1 diabetes mellitus (T1DM) results from a defect in insulin secretion in the body. T1DM may happen at any age and it is one of the most common chronic diseases of childhood and adolescents (Misso, Egberts, Page, O’Connor, & Shaw, 2010). Long-term complications of T1DM include retinopathy, nephropathy, neuropathy, and cardiovascular disease. There is no prevention or cure for T1DM, and the treatment is a life-long insulin replacement regimen. Proper and accurate glycemic control is critical to…

Introduction: Type 1 Diabetes Mellitus is a disease that occurs when insulin-producing beta cells of the pancreas are damaged or are being destroyed (Mahan, Escott-Stump & Raymond, 2012). The gradual destruction of the beta cells of the pancreas usually leads to complete insulin deficiency, which ultimately manifests itself in the following symptoms at clinical onset: “high blood glucose (hyperglycemia), frequent urination (polyuria), excessive thirst (polydipsia), and a significant amount of weight…

Table of Contents I. Introduction to Type 1 Diabetes Mellitus a. What it is b. Prevalence and demographics c. Treatment II. Cognitive Outcomes: Mood and Memory a. Memory i. Neural Basis of Memory ii. Cognitive Outcome of TIDM on Memory III. Structural Brain Changes: MRI Studies a. The Hippocampus i. Purpose and Function of the Hippocampus ii. Previous studies on T1DM and Hippocampal Volume iii. The Cognitive Effects of T1DM on Hippocampal Volume b. Other Brain Areas IV. Conclusion a…

to The American Diabetes Association, “Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of various organs, especially the eyes, kidneys, nerves, heart, and blood vessels” (p.1). There are two types of diabetes, type 1 and type 2. Insulin management is needed for type 1 diabetes, because it is…

Introduction: Type 1 Diabetes Mellitus is a disease that occurs when insulin-producing beta cells of the pancreas are damaged or are being destroyed (Mahan, Escott-Stump & Raymond, 2012). The gradual destruction of the beta cells of the pancreas usually leads to complete insulin deficiency, which ultimately manifests itself in the following symptoms at clinical onset: “high blood glucose (hyperglycemia), frequent urination (polyuria), excessive thirst (polydipsia), and a significant amount of weight…

Type 1 Diabetes Mellitus, also known as insulin dependent diabetes mellitus (IDDM) is destroys pancreatic beta-cells, leading to partial or total loss of insulin production (Merger, et al 170). The exact cause is not known, but the destruction is triggered as an autoimmune response which could be due to the stressors from environment and genetics (Merger, et al 170). “Type 1 diabetes is a chronic condition in which there is no cure, nor prevention at the current time” (Merger, et al 170). Most…

receptor sensitivity. Chronic hyperglycemia of diabetes leads to microvascular and macrovascular complications 1 CLASSIFICATION 1 • Diabetes mellitus type 2 ○ Accounts for 90-95% of cases of diabetes ○ Less common types of diabetes include: diabetes mellitus type 1, gestational diabetes, diabetes due to genetic defects, drug-induced diabetes, endocrinopathy based diabetes, exocrine pancreas based diabetes DIAGNOSIS CLINICAL PRESENTATION • History 1, 14 ○ May be asymptomatic despite pathological…

Maggie Roman MED 2056 Cohort FT31 Diabetes Mellitus Mrs. Annabelle June 29, 2015 The human body achieves homeostasis through the coordination of organs and different systems throughout the body. In particular, the endocrine system plays a functional role in regulating the body’s physiological activities via chemical substances, known as hormones. The endocrine cells secrete hormones in response to body signals in a negative feedback loop, which is a self-regulatory response intended…

Type 1 diabetes mellitus is an autoimmune disease that results in insulin dependence due to failure of secretion of the hormone insulin by beta cells in the pancreas. Type 1 diabetes usually manifests in childhood, < 20 years of age – the reason for which it was formerly termed juvenile diabetes, and is more prevalent in Caucasians then in any other ethnicity (Diabetes Basics, n.d.). The key to proper management is early detection, patient education, and most importantly patient compliance. The…