Diabetes The Endocrine System Consists Of Elevated Or Inadequate Depression Of Endocrine Gland

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Diabetes In diabetes the endocrine system comprises of elevated or inadequate depression of endocrine gland with results in alterations in hormone levels. “Diabetes affect 25.8 million people, or 8.3% the U.S. population, have diabetes and another seven million are estimated to be undiagnosed” (Huether & McCance, 2012, P.447). Diabetes Insipidus “Diabetes Insipidus (DI) is a disorder of insufficient activity of ADH, leading to polyuria (frequent urination) and polydipsia (frequent drinking)” (Huether & McCance, 2012, P.449). There are two forms, neurogenic or central DI can occur with injury or some drug to posterior pituitary gland interferes with abnormalities in ADH secretion. Second nephrogenic is failure of the renal tubes to concentrate urine in respond to ADH. In DI the individual has difficulty concentrating urine whether partial or total. The lack of ADH allows filtered water to be excreted in the urine instead of reabsorbed. Results in excretion of large volumes of dilute urine, leading to increase plasma osmolality. The disorder triggers excessive urination and thirst and fluid intake. Urine output can range from 1 to 2 liter/day averaging 8 to 12 liter/day with low specific gravity. Loss of fluid output without replacement the individual can rapidly develop dehydration. The individual that is unable to maintain the appropriate water balance hypernatremia and hyperosmolality will occur. Laboratory test a 24hour urine, serum electrolyte and glucose level. Urine

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