Diabetes mellitus is a chronic metabolic disease characterized by high blood glucose levels

Type 1 is characterized by the body’s inability to produce insulin. It is caused by autoimmune-mediated destruction of pancreatic beta cells, which are responsible for producing insulin. There appears to be a hereditary link in people with Type 1 diabetes. Other factors have been known to cause Type 1 diabetes such as viral infections, toxins, and other environmental factors. Type 1 diabetes is the rare form, affecting about 10% of the diabetes population. Its onset usually occurs in people less than the age of 20.

Uncontrolled diabetes can affect nearly every organ of the body; of which, heart disease and kidney failure are most commonly impacted. Known as diabetes mellitus, a collective term for various blood abnormalities, the term diabetes refers to either a scarcity of insulin in the body or the body’s inability to accept insulin. Though the symptoms of diabetes are manageable, many are unaware as to having it. According to the CDC report “2011 Diabetes Fact Sheet,” approximately 6 million people in the United States have undiagnosed diabetes. Undetected, diabetes can become deadly. In a recent World Health Organization report “Diabetes Action Now: An Initiative of the World Health Organization and the International Diabetes Federation,” it

Diabetes is a growing concern and health challenge for the American people (b). Diabetes is a condition in which the body cannot react to insulin appropriately or either cannot produce insulin efficiently (w). “Without a properly functioning insulin signaling system, blood glucose levels become elevated and other metabolic abnormalities occur, leading to the development of serious, disabling complications” (w). There are numerous forms of diabetes amongst the nation, however, there are three main forms of diabetes. Most people have heard of type one diabetes, type two diabetes, and gestational diabetes because they are common. Type two diabetes deals with a resistance to insulin, while

Type 1 diabetes, also referred to as Insulin Dependent Diabetes Mellitus (IDDM) or Juvenile Diabetes, can be caused by a genetic disorder. It can occur at any age, but it is most often diagnosed in children, adolescents, or young adults around 20 years old or before a person is 30 years of age. Insulin is a hormone produced by special cells, called the beta cells, in the pancreas, an organ located in the area behind the stomach. Insulin is needed to move blood sugar (glucose) into cells, where it is stored and later used for energy. In type 1 diabetes, these cells produce little or no insulin. Without enough insulin, glucose builds up in the bloodstream instead of going into the cells. The body is unable to

Type 1 diabetes is a life long auto-immune condition where the immune system is activated to destroy the cells in the pancreas that produce insulin. Scientists are not sure what causes this auto-immune reaction (Vanstone et al. 2015). It can occur at any age, although it is most often diagnosed in children, adolescents or young adults. The immune system incorrectly sees the insulin-producing cells in the pancreas as foreign, therefore it destroys them. The role of these insulin-producing cells is to sense glucose in the blood, and in response produce the essential amount of insulin to regulate the blood sugar (Griffiths & Payne 2014 pp. 390-391). Insulin’s role is to get glucose from the bloodstream into the body’s cells. Without insulin,

Type 1 diabetes (T1D) results from a T cell-mediated autoimmune destruction of the beta cells of the pancreas. The destruction of the beta cells ultimately leads to insulin deficiency. Beta cells autoimmunity is triggered by a combination of genetic and environmental factors (Huether & Mccance, 2012).

Diabetes is often referred by doctors as diabetes mellitus. It is a group of metabolic diseases in which the person has high blood glucose, either because insulin production is insufficient or because the body’s cells do not respond properly to insulin. Insulin is necessary to keep blood glucose level stable in the body, It is a hormone produced in the islets of langerhans in the pancreas, it is important for metabolism and utilization of energy from the ingested nutrients especially glucose (DiabetesUK).

Diabetes, often referred to as diabetes mellitus, is one of the leading chronic diseases. Diabetes is a group of diseases marked by high levels of blood glucose, also known as hyperglycemia, resulting from problems in the body’s ability to produce insulin, the body’s effective use of insulin, or both (Centers for Disease Control and Prevention, 2014). The food we eat on a daily basis is broken down into glucose and enters the bloodstream. Insulin, a hormone made by the pancreas, is then used to transform glucose into energy by letting them into the cells (Centers for Disease Control and Prevention, 2014). Therefore, insulin is very important because it regulates the blood sugar in our body. High levels of blood glucose increases the risk of heart attacks, strokes, blindness, kidney disease, and limb amputation (Centers for Disease Control and Prevention, 2014). According to International Diabetes Federation, over 387 million people have diabetes worldwide. It is projected that by 2035, this number will rise to 592 million (Atlas, 2013). In 2012, a total of 29.1 million people or 9.3% of the United States population have diabetes (Centers for Disease Control and Prevention, 2014). That’s about 1 out of every 11 people. According to 2010 statistics, diabetes is the seventh leading causes of death in the United States (Centers for Disease Control and Prevention, 2014). The estimated diabetes costs in the United States for 2012 was $245 billion, which

Diabetes is a common chronic disease that causes problems in the way the blood uses food. The inability of the body to transform the sugar into energy is called diabetes. Glucose is the primary source of fuel for our body. When foods are digested, some of those foods are converted into glucose. Glucose then is transferred into the bloodstream and is used by cells for energy. However, for the glucose to be transferred from the blood into the cells, insulin, which was produced by beta cells in the pancreas is needed. In individuals with diabetes, this process is impaired. Currently, the disease affects approximately 371 million people of the world 's population with incidence and prevalence rates rising rapidly (Alotabi, A.,

In type 1 diabetes, the immune system which normally fights harmful bacteria or viruses – attacks and destroys the insulin-producing Beta cells in the pancreas (autoimmunity). This type of diabetes results from the loss of the insulin-producing beta cells produced by the pancreas, leading to insulin deficiency. Type 1 diabetes can be classified as an autoimmune disease in which the T-cells destroy the beta cells.

Type 1 diabetes is an autoimmune disease that begins when the pancreas quits making insulin. Insulin plays a key role by letting glucose enter the body’s cells, and then uses it for energy. When the body doesn’t get the

Many have a misconception in regards to diabetes. Type I diabetes is due primarily to autoimmune-mediated destruction of pancreatic beta-cell islets, resulting in absolute insulin deficiency. People with type I diabetes must take exogenous insulin for survival to prevent the development of ketoacidosis. Its frequency is low compared to type II diabetes, which accounts for

Diabetes Mellitus (DM) is a serious, chronic disease which affects one out of every eleven people in the United States. Diabetes Mellitus, also known as Diabetes, is a complex endocrine disease dealing with excessive glucose in the blood. The disease process lies within the body’s metabolic state in which the body metabolizes carbohydrates, proteins, and fats leading to either defective insulin production or insufficient amounts of insulin. Diabetes has several pathogeneses, signs and symptoms, risk factors, complications, treatment goals and teaching practices. In this paper, I will discuss the complex nature of Diabetes and its effects on the human body.

Type 1 diabetes (insulin-dependent), often develops in childhood or early adulthood and is the outcome of the reaction of the autoimmune system which is produced as a result of the destruction of beta cells from the pancreas, when the body does not produce insulin. This usually happens because the insulin secreting cells of the pancreas do not function, or they are simply not there, have been destroyed or they are in small quantities that they cannot produce any insulin to properly control blood sugar levels. Since insulin is necessary to sustain life, the missing insulin has to be replaced and it is managed with regular insulin injections, the dose which is

Diabetes Mellitus, more commonly known as type 1 diabetes and type 2 diabetes, is a disease that causes destruction or dysfunction of β cells, which are cells in the pancreas that secrete insulin (1). Having dysfunctional β cells leads to a deficiency in insulin, which in turn limits the uptake of glucose into the cells (2). Currently, diabetes does not have a cure; it is managed by close glucose monitoring and injection of exogenous insulin (1). However, only with these methods, it is difficult to control the blood glucose levels in a range that is considered normal (3). As low blood sugar poses an immediate danger, and continued high blood sugar leads to serious life threatening consequences – such as cardiovascular disease, diabetic