Diagnostic Study On Celiac Disease

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Diagnostic Study:

Diagnostic Study

Rational

Result

CBC with deferential

-CBC is an inexpensive, frequently used test to complement the clinical history and physical examination in the patients with gastrointestinal diseases.

-Gastrointestinal diseases: Though iron is absorbed throughout the intestine, it is maximally absorbed in the duodenum. Diseases involving the duodenum – Celiac disease, Crohn’s disease and giardiasis, thereby are important etiologies. Increased gastrointestinal loss as seen in inflammatory bowel disease (IBD), cow’s milk protein induced colitis and chronic use of nonsteroidal anti-inflammatory drugs are also associated with iron deficiency (Subramaniam and Girish, 2015).

All the results within normal
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Not done at this time
Iron panel
To check iron storage in patient with celiac. In addition, Iron and folate anemia are seen more often in people with celiac disease because these nutrients are absorbed in the upper two parts of the intestine where damage can occur in earlier stages of celiac disease (Reop, 2017).

Not done at this time
Thyroid function test
To rule out thyroid problems, which is usually associated with celiac disease. The prevalence of autoimmune thyroid disease in patients with celiac disease is four times greater than that in the general population, and this may be due to the common genetic predisposition (Kurlen, 2016).

Not done at this time
Small bowel biopsies
Gold standard to diagnose celiac disease in patient. An intestinal (duodenal) biopsy is considered the “gold standard” for diagnosis because it will tell you (1) if you have celiac disease, (2) if your symptoms improve on a gluten-free diet due to a placebo effect (you feel better because you think you should) or (3) if you have a different gastrointestinal disorder or sensitivity which responds to change in your diet (Kabbani, 2014).

Not done at this time

Assessment:

Celiac disease: This is a 5years old boy presented with a history of periumbilical pain for two months associated with bloating, gasses and change in appetite. Also, bowel motion alternating between diarrhea and constipation since that time.
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