Diamingham Risk Prediction Model

BMI was calculated at the time of diagnosis, we used measured weight and height to calculate BMI (kg/m2). According to the World Health Organization Guidelines, Patients were classified into 2 levels: patients with BMI (<25 kg/m2) were categorized as level I and patients with BMI (P25 kg/m2) were categorized as level II. Clinicopathologic and outcome data were tested for its relation with BMI. Statistical analysis Data were analyzed by using SPSS version 17 (SPSS Inc., Chicago, IL, USA) and has been subjected to descriptive analysis.

Why do we treat diabetes? There are a number of downstream events associated with abnormal blood glucose levels. If glucose levels are managed properly, the complications associated diabetes can be controlled, and sometimes completely prevented. The main problem with having more than the normal amount of glucose circulating in the blood stream is the effect that excess glucose can have on both large and small blood vessels (DTC, 2004). Micro-vascular and macro-vascular problems associated with diabetes can be seen in the heart, eyes, kidney, legs and feet. Diabetic patients are twice as likely to suffer from a mycocardial infaraction, twenty-five times more likely to suffer blindness, and seventeen times more likely to suffer kidney failure compared to a non-diabetic (DTC, 2004). Because of great number of risks associated with abnormal blood glucose levels, diabetes is aggressively treated to improve the quality of life and prevent complications in patients.

Diabetes is a disease where the body is unable to produce or use insulin effectively. Insulin is needed for proper storage and use of carbohydrates. Without it, blood sugar levels can become too high or too low, resulting in a diabetic emergency. It affects about 7.8% of the population. The incidence of diabetes is known to increase with age. It’s the leading cause of end-stage renal disease in the US, and is the primary cause of blindness and foot and leg amputation. It is known to cause neuropathy in up to 70% of diabetic patients. Individuals with diabetes are twice as likely to develop cardiovascular disease. There are two types of diabetes: Type 1 and Type 2.

The American Diabetes Association (2004) defines diabetes as a subset of metabolic diseases associated with hyperglycemia secondary to insulin failing to release, act, or both. Complications related to chronic diabetes can be detrimental to one’s health including but not limited to: heart disease, stroke, kidney disease, amputations, blindness, and other optical diseases. Furthermore, the prevalence of diabetes is rising at an astronomical rate within the United States as well as internationally. According to the Center for Disease Control and Prevention (CDC) (2016) an estimated 29 million people suffer with diabetes and 86 million are prediabetic within the United States (US). Without major interventions from the healthcare community,

Diabetes mellitus (DM) is a pandemic that affects millions of people. The growth rate of unrecognized pre-diabetes in America is expected to rise up to 52% by 2020 (Lorenzo, 2013). As the prevalence of diabetes increases, so will the complications and burden of the disease. One of the leading causes for cardiovascular disease, renal failure, nontraumatic lower limb amputations, stroke, and new cases of blindness is DM (Lorenzo, 2013).

Uncontrolled diabetes can affect nearly every organ of the body; of which, heart disease and kidney failure are most commonly impacted. Known as diabetes mellitus, a collective term for various blood abnormalities, the term diabetes refers to either a scarcity of insulin in the body or the body’s inability to accept insulin. Though the symptoms of diabetes are manageable, many are unaware as to having it. According to the CDC report “2011 Diabetes Fact Sheet,” approximately 6 million people in the United States have undiagnosed diabetes. Undetected, diabetes can become deadly. In a recent World Health Organization report “Diabetes Action Now: An Initiative of the World Health Organization and the International Diabetes Federation,” it

Diabetes is a chronic illness that requires continuous medical care and patient self-management education to prevent acute complications and to reduce the risk of long-term complications[ ].

Diabetes Mellitus is a growing issue for health care providers internationally. The World Health organization estimated in 2013 there were 347 Million diabetics worldwide, predicting that Diabetes will be the 7th leading cause of death by 2030 (WHO, 2013). In both type 1 and type 2 diabetes Mellitus, factors such as poor compliance with diet and medication, infection, acute medical or surgical illness or trauma can lead to poor glycaemic control, precipitating a hyperglycaemic emergency such as Diabetic Ketoacidosis (DKA) (Scobie & Samaras, 2009). In Type 2 Diabetes, another equally dangerous

However, because Danny does have diabetes, his health is in a poorer state and his risk for developing cardiovascular disease is increased. Diabetes is defined as having a fasting plasma glucose value of 7.0 mmol/l (126 mg/dl) or higher. Every year, diabetes claims many lives; for example, in 2008, diabetes was responsible for 1.3 million deaths all across the world (World Heart Federation, N.p., n.d). When looking at cardiovascular disease with diabetes, data shows that of all diabetics who die, 60% of them die as a result of cardiovascular disease (World Heart Federation, N.p., n.d). Cardiovascular risk increases with raised glucose values. The risk of cardiovascular events is from two to three times higher in people with type 1 or type 2 diabetes and the risk is disproportionately higher in women (World Heart Federation, N.p., n.d). From this we can infer that if my mother or I did have diabetes, it would be likely that that would increase our risk to a greater degree compared to Danny’s risk, because he is a male. Cardiovascular risk increases with raised glucose values. In addition, within certain age groups, people with diabetes have a two-fold increase in the risk of stroke. Patients with diabetes also have a poorer prognosis after cardiovascular events compared to people without diabetes. Primary care access to measurement of blood glucose and cardiovascular risk assessment as well as

Amongst the many people suffering from heart diseases worldwide, a good percentage of them are in the developed countries. These are people diagnosed with Diabetes or not, but are at high risk of heart diseases, even to a fatal level to about 50% (Al-Nozha, Ismail and Al-Nozha, 2016). Most of the people with heart complications are also likely to suffer diabetes, which adds to the complications of the illness. According to (2016), at least 50% of the deaths are a result of circulatory diseases while 75% of deaths result from coronary artery disease. Further notes highlight that at least 70% of the patients suffering heart diseases and diabetes are likely to succumb to death within ten years. Therefore, a solution for heart disease and diabetes management is fundamental to a healthy society.

Standardized questionnaire, physical examination, and laboratory tests were included in this survey. Specially trained doctors and nurses performed all data collections. A face-to-face interview was conducted to collect demographic (e.g. age and gender) and clinical data (e.g. smoking status, alcohol consumption level, exercise habits, history of diabetes mellitus, history of hypertension and use of antihypertensive drugs) by self-reporting, standardized questionnaires. As in our previous study, physical examinations involved assessments of height, weight, and waist circumference 11-12-. BMI was calculated using the following formula: weight/height2 (kg/m2). Fasting plasma glucose (FPG), fasting serum total cholesterol (TC), low-density lipoprotein

Diabetes is a major problem in our society today. Many people have heard about the disease; however, they do not know too much about its complications. Diabetes is a chronic, progressive and lifelong condition that affects the body’s ability to use the energy found in food (WebMD, 2016). Many new cases are confirmed every year and unfortunately, many go undiagnosed for years. Diabetes is a serious disease and need to be taking seriously. The disease can lead to many other health problems such as blindness, nerve damage and kidney diseases. The more the community understand and made aware of the seriousness of the disease, the better it can be control and or prevented.

Diabetes Mellitus is “a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. It is a disease which is caused by the insufficient insulin secretion or decrease in the peripheral effects of insulin. It is a serious problem in terms of morbidity and mortality. The hyperglycemia is associated with long term damage, dysfunction and failure of various organs especially the eyes, kidneys, nerves, heart and blood vessels. It’s associated with many complications which includes blindness of the eyes and amputations of the extremities. It is also associated with neuropathy, retinopathy, and cardiovascular diseases which lead to mortalities.

It is known that diabetes is positively associated with the CVD risk. One of the limitations of the Framingham risk score is the small number of diabetic people in a cohort of 5573 individuals (4%) and also the diabetes definition was based on a random blood glucose concentration >9 mmol/L or the use of anti-glycemic treatment. Hence, the accuracy of the Framingham risk score for CV risk assessment in diabetic patients has been addressed in previous studies [44]. The most widely used risk score in the European countries, SCORE [6], also lacks the risk prediction power of diabetes because of the

Diabetes is a systemic disease caused by a decrease in the secretion of insulin or reduced sensitivity or responsiveness to insulin by target tissue. (Beale, et al., 2011) The incidence of diabetes is growing rapidly in the United States and worldwide. An estimated 347 million people around the world are afflicted with diabetes. (Whalen, et al., 2012) According to World Health Organization (WHO), Diabetes prevalence among adults over 18 years of age has risen from 4.7% in 1980 to 8.5% in 2014. It is the major cause of blindness, kidney failure, heart attack, stroke and limbic amputation. World Health Organization (WHO) projects that diabetes will be the 7th leading cause of death in 2030. It is a complex and costly disease that can affect nearly every organ in the body and result in devastating consequences. The leading cause of non-traumatic lower extremity amputations, renal failure, and blindness in working-age adults, diabetes is also a major cause of premature mortality, stroke, cardiovascular disease, peripheral vascular disease, congenital malformations, perinatal mortality, and disability. (Cefalu, 2000) Insulin therapy and oral hypoglycemic agents have demonstrated improvement in glycaemic control. However, Insulin therapy has some disadvantages such as ineffectiveness following oral administration, short shelf life, of the need for constant refrigeration, and fatal hypoglycaemia, in the event of excess dosage.