Different Types Of Hemophili Blood Clotting

Hemophilia is a rare blood condition in which an individual’s blood cannot clot appropriately to stop bleeding. There are two types of Hemophilia, Hemophilia A and Hemophilia B. This paper will be focusing on Hemophilia A, also known as classic hemophilia. “Hemophilia A is a genetic disorder caused by a missing or defective factor VIII, a clotting protein” (National Hemophilia Foundation, n.d., para. 1). Clotting proteins work with cell fragments called platelets to stop bleeding. “When blood vessels are injured, clotting factors help platelets stick together to plug cuts and breaks on the vessels and stop bleeding (National Heart, Lung, and Blood Institute, 2013, para.

Lastly hemophilia C is the rarest and occurs in 1 in 100,000 of the general population. Most people have the severe type of this disorder. Hemophilia doesn’t occur mainly to a specific race but mainly occurs in men because hemophilia is an X-linked disorder. To make a diagnosis doctors take a blood test to determine if blood is clotting correctly, if not doctors will do clotting factor tests, called factor assays to conclude the type and severity of hemophilia that the patient has. As of today there are no known cures for hemophilia yet, but there are some treatments available for the bleeding and symptoms of this mutation. The main treatment for the symptoms of hemophilia is injecting the clotting protein into the patient's vein, this is called replacement therapy, these injected proteins can be made from human blood, there is a small chance that a patient being treated with another humans blood can get an infectious disease. However to prevent getting that you can take the treatment that is not made from human blood, called recombinant clotting factors. This treatment can be easily used and stored at home and can take fifteen minutes to receive

Hemophilia is the oldest known hereditary bleeding disorder. There are two types of hemophilia, A and B (Christmas Disease). Low levels or complete absence of a blood protein essential for clotting causes both. Patients with hemophilia A lack the blood clotting protein, factor VIII, and those with hemophilia B lack factor IX. A person with severe hemophilia has less than 1% of the normal amount of a clotting factor - either Factor VIII (8) or Factor IX (9). People without hemophilia have between 50-150% of the normal level of factor VIII or IX. There are about 20,000 hemophilia patients in the United States. Each year, about 400 babies are born with this disorder. Approximately 85% have hemophilia A and the remainder has hemophilia B.

A. It 's important to know that hemophilia is not actually a disease or virus. https://my.clevelandclinic.org calls hemophilia "a rare hereditary (inherited) bleeding disorder in which blood cannot clot normally at the site of a wound or injury". This means that it is not contagious, rather it is passed down through genetics. When a hemophiliac gets injured,

Hemophilia : Normally the blood clots in a few seconds, but in Hemophilia which is a rare disorder the blood does not clot normally as it is deficient in blood clotting proteins also called the clotting factors.So in any case if you are suffering from Hemophilia then the blood will take a much longer time to clot than normal .Small injuries are not much of a worry but its of greater concern if there is any internal bleeding which may cause a severe damage to internal organs.

Hemophilia A is the most common clotting disorder which “…accounts for approximately 85% of… [Hemophilia cases].” (Copstead-Kirkhorn, 2012, pp. 304) The cause for this clotting disorder is the deficiency of clotting factor VIII. With this factor lacking, a patient can experience abnormal bleeding accompanied by a prolonged clotting time. This disorder is also classified as X-Linked recessive. Thus, if the father has Hemophilia A and the mother does not, there is a 50% chance that the sons will have the disorder and 50% chance that the daughters will be a carrier of the disorder. It only takes one infected X chromosome to spread

Within today’s society there are hundreds of diseases that can be broken down into the subcategories of preventable and non-preventable. For example, sexually transmitted diseases can be categorized as preventable as long as an individual can remain abstinent. It is always reassuring that with a healthy and sustained lifestyle, you can decrease your chances of developing any harmful effect to your body. Unfortunately, preventable is not always the case. A randomized group of people can either be born with or develop a non-preventable disease.1

Hemophilia is a group of hereditary genetic disorders that affects the body’s ability to cause blood clotting which stops bleeding after a blood vessel is broken. According to Zerwekh, Miller, & Cliburn (2012) hemophilia is a rare condition with only about one instance in every 1000 births for hemophilia type A and one in every 50000 births for hemophilia type B. In total only around 18000 people are hemophilic in the United States of America. Every year in the U.S, around 400 babies are born with the disorder ("Home | Hemophilia | NCBDDD

There are symptoms of Hemophilia A and Hemophilia B. They are: Big Bruises, Bleeding into muscles and joints, Spontaneous bleeding (sudden bleeding inside the body for no clear reason), prolonged bleeding after getting a cut, removing a tooth (or having surgery), and also bleeding for a long time after an accident (especially after an injury to the head).

Hey do you know what hemophilia is? Well it's a bleeding disorder, when you bleed too much when having an injury making you have too much blood loss. There are treatments that can help you if you have Hemophilia ,but sadly we have no cure for it yet. When you have Hemophilia you have to stay away from things that can hurt you like when you are reading a book you have to be careful because you don't want a paper cut.The treatments that can help you when you have replacement therapy, replacement therapy is a treatment aimed at making up a deficit of a substance normally present in the body.

Hemophilia (sometimes spelled haemophilia) is a rare genetic blood disorder which prevents blood from clotting normally. There are two types of hemophilia, and they are hemophilia A and hemophilia B. Hemophilia A is also called classic hemophilia, and is caused by a mutated or missing factor VIII, which is a clotting protein. Hemophilia B is sometimes called Christmas disease, because the disorder was first reported in a patient with the last name Christmas. Hemophilia B is caused by a mutated or missing factor XI, which is also a clotting protein.

Normal mechanisms for blood clotting involve interactions between injured blood vessels, platelets, and over 20 different proteins that circulate the blood.

with wounds that have broken through the skin, WBCs will gather around the point of entry to fight infection and prevent any further damage to systems (Tortura 699). However, in the case of hemostasis, the most important contributors are the Platelets, cell fragments that are held together with a membrane (702). As bleeding occurs, various chemicals and enzymes that are contained within platelets activate, causing the cells to become sticky and encourage accumulation to one another. This coagulation of platelets at the broken vessel’s entry site will eventually form a solid plug, resulting in effective clotting. . Clotting is essential to stop major bleeding of vessels throughout the body, especially in the case of hemorrhagic or hypovolemic shock

They are also easily prone to internal bleeding. The process of blood clothing over an injured area involves steps . Platelets are blood cells that found in the blood that are responsible for the clotting of blood. Fiest Platelets cells form a plug that sticks to the damaged area, and then it is covered by a fiber that is like a lasting bandage to the injured area (human disease). In the formation of fibrin, their are thirteen different chemicals that are involved known as clotting factors (human disease). This is one of the chemicals hemophiliacs lack or they don't have enough amount in their body and their body may not be able to form fibrin when there is a small cut or a severe damage. Different groups of hemophilia have been discovered (human disease). Type A, B, and C. Out of this three types type A hemophilia is the common one, it is caused by the deficiency of factor VIII (Kahn, A). Type A and B hemophilia can be mild moderate or severe. According to the NHLBI, 8 out 10 people have hemophilia and 7 out of ten people will have a severe case of hemophilia (NHLBI). Type B and type A, hemophilia have similarities but hemophiliac's with type B have a low level of IX clotting (NHLBI). The other type of hemophilia is type C which is the mildest form of hemophilia and caused by a deficiency of clotting factor XI (mayo

Occasionally a baby is born with this disorder and no family history of it. When this happens, it could be caused by a hidden gene, which is when several generations of female carry it, and it has not affected any male members of the family or a spontaneous mutation. With each pregnancy, a woman who is a carrier has a 25% possibility of having a son born with hemophilia. Since the father's X chromosome is what determines if the unborn child will be a girl, all of the daughters born of a man with hemophilia will be carriers. None of his sons, which is determined by the father through his Y chromosome, will have hemophilia. Individuals who suffer from mild hemophilia may choose to use a non-blood product known as Desmopressin acetate (DDAVP) to help treat the small bleeds and/or scrapes. For deep cuts or internal bleeding, the treatment called DDAVP may not be enough and therefore, may need a much more complex treatment. The clotting factor must be replenished so the affected person can form a clot to stop the bleeding. Plasma is one of the ‘human blood products’ than is used for factor replacement. Another factor replacement option is using the recombinant factor, which is produced in a laboratory.