Sickle Cell Disease: A Case Study

Sickle Cell Disease is an illness that affects people all across the globe. This paper will give a description of the sickness through the discussion of the causes, symptoms, and possible cures. Sickle Cell Disease (SCD) is a "group of inherited red blood cell disorders."(1) These disorders can have various afflictions, such as pain, damage and a low blood count--Sickle Cell Anemia.

Sickle cell crisis is an acute form of sickle cell disease where pain and sickling are extensive (Byar, 2013). SCD is a genetic disease that predominantly affects black people of African decent (Gersten, 2016). Abnormal hemoglobin chains are the main issue with SCD (Byar, 2013). Normal hemoglobin chains are comprised of 99% hemoglobin A (HbA) however, in SCD an abnormal form of the gene, hemoglobin S (HbS) is present in approximately 40% of total hemoglobin (Byar, 2013). In order for a person to be born with SCD, both parents must carry the abnormal gene, HbS (Byar, 2013). HbS is extremely sensitive to the changes in oxygen amount of the RBC and when exposed to decreased oxygen the HbS cause the RBC to distort and become sickle-shaped,

This mutation paper is to give information on the Sickle Cell disease. This is a negative disease to have because the Sickle Cell Disease decreases the health of the person that has the disease and limits what they can and cannot do. Sickle Cell Disease is a red blood cell disease that causes ab normal hemoglobin to from in the veins. Hemoglobin is the protein that carries oxygen throughout the body to help with the respiratory system. The cause of the genetic mutation is inheritance or getting the disease from the parents the disease is found on chromosome 13 while the hemoglobin is still in beta phase on gene HB A. The disease typically shows symptoms within the first 5 to 6 months of birth and being diagnosed with Sickle Cell Disease. The symptoms include painful swelling on the hands and feet, and Jaundice, which causes a white color to form under the eyes, and turns the skin color yellow.

Thank you for sharing your post regarding the Interprofessional and collaborative practice in managing sickle cell disease. You have highlighted the core competencies of Interprofessional collaboration, illustrated the communication forms applied in your capstone project and indicated the most relevant domain as understanding the role and responsibility of each member. I absolutely agreed with you that sickle cell patients require care coordination approach to effectively manage pain and complications associated with sickle cell episode.

Sickle Cell Disease or also widely known as Sickle Cell Anemia is a genetic mutation caused in red blood cells destroys its own cells within and reshaping the cell wall resembling crescent or sickle shape; getting its name of the sickle cell disease. These sickled shaped cells attempt to perform its normal function of circulating oxygenated and deoxygenated RBC and gets lodged in small vessels causing vaso-occlusion. Where vaso-occlusive take effect, rest of the body is not receiving oxygen becoming oxygen deprived results in acute and chronic pain and organ damage (Valerie Mann-Jiles, 2015). This disease a lifelong condition affecting not just the person carrying the disease but the whole family. Treating this disease

Locate, cite (quote or paraphrase) and share a reliable information source(s) that discusses a degenerative disease experienced at a higher rate among Black/African Americans (vs. American majority statistics)

The term sickle cell infection (SCD) depicts a gathering of acquired red platelet issue." Normal red blood cells are shaped like discs or donuts. They are soft and flexible so they can easily move through very small blood vessels"(anonymous, 2015).Individuals with SCD have anomalous hemoglobin, called hemoglobin S or sickle hemoglobin, in their red platelets. Hemoglobin is a protein in red platelets that conveys oxygen all through the body. The most well-known sort is known as, sickle-cell frailty (SCA) and there is A few Types of Sickle Cell Sickness: Hemoglobin SS, Hemoglobin SC, Hemoglobin SD. In the Unified States, a great many people with sickle cell illness (SCD) are of African family line or recognize themselves as dark. About1 out of 13 African American children is

Sickle cell disease (SCD) is a destructive abnormality in red blood cells that results in circulatory impairment. Sickle cell disease can cause pain, infection, organ damage and strokes. SCD is inherited through the infants’ parental genes (James, 2014). For instance, if an infant inherits the gene from one parent that infant will automatically have the sickle cell trait. As a result, the infant will be a carrier of the disease but won’t actually have the SCD. It is very rare for a carrier to have any symptoms. Women who have SCD are considered high risk if they become pregnant. SCD poses complication for both mother and fetus during

Sickle cell anemia (SCA) is an inherited disease of the blood that is characterized by the production of abnormal hemoglobin S causing the cell to acquire a sickle shape that prevents the smooth flow of blood to a major organ (Shea et al. 2017). The stress is usually caused by fever, infection or cold temperature, which lead to sickle cell crisis caused by hypoxia, dehydration, and acidosis (Barranger, 2017).

Sickle cell anemia mainly affects people with African, Mediterranean, Middle Eastern, and Indian ancestry. A person with sickle cell anemia inherits two sickle cell genes, one from each parent. It cause the red blood cells to change and become crescent shaped. Normal red blood cells are disk shaped and move easy through the blood vessels. The primary problem is hemoglobin, it is a protein molecule in red blood cells that carries oxygen from the lungs to the body’s tissues and returns carbon dioxide from the tissues to the lungs. In sickle cell anemia, the hemoglobin is flawed. The cells become sickle shaped and can’t move as easily through blood vessels. Sickle cell anemia has one main cause, in order for sickle cell anemia to happen, a sickle

Sickle cell disease is a chronic condition that a person can inherit from their parents in which it effects the globular structure of the patients red blood cells. A more sickle shaped structure, which can alter a person’s blood flow, replaces the more common globular structure. This impairment in blood flow can lead to blood clots, severe debilitating pain and damage to vital organs such as the liver, kidney and spleen. This disease currently affects over 90,000 people in the United States, with the majority of them being African American and

The basic life-span of an affected cell is generally from 1.5 to about 3 weeks, which represents approximately 10% to 20% of a normal cell's life. Because they cannot be replaced fast enough, the

CVA related to Sickle Anemia (SCA) with crisis is the primary admitting diagnosis for a 45 year old Hispanic client with a history of DM type 2, HTN, CHF and sickle cell anemia who came to the emergency room after waking up to left sided weakness, blurry vision, and occipital headache, with SOB and chest pain upon waking at 0430 am. SCA is a genetic disorder that causes a malformation of the hemoglobin cells that are attached to the red blood cells causing a decrease in the cell oxygen carrying capacity. Hemoglobin in itself is a protein that binds iron and oxygen to the cells and because the shape of the SCA cells are deformed; the surface area for bonding is decreased therefore the name sickle cell is characteristic of its formed shape.

When they diagnosis a patient with Sickle Cell Anemia they perform a blood test. This test would check for hemoglobin S which is what carries oxygen to all the tissues. This would service as a conformation that an individual does indeed contains the disease. This blood test is a routine performed with newborns at birth in the hospitals; however, it can be tested on adults as well. What is test from newborns to determine if the disease is present is by extracting a sample of the amniotic fluid. The blood is usually taken form newborns from there heel or finger. Whereas, adults are taken from the vain in the arm. Once they conclude if its negative or positive further test will be done to see if there are one or two sickle cells existing.

Sickle Cell Anemia is a group of disorders that cause red blood cells to become misshapen and break down. Sickle cell disease is the most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans (Ashley-Koch, Yang and Olney). Sickle Cell Anemia causes your red blood cells to be thin, stiff, and shaped like a sickle. But your red blood cells are supposed to be round and soft. A person that is diagnosed with sickle cell anemia, their blood cells start to become clogged, causing blood clots, which can cause a great amount of health issues including: infections, stroke, and acute chest syndrome. People get sickle cell anemia by inheriting a mutated gene from both of their parents. On the down side, there is not currently an effective cure for sickle cell anemia, there are several different therapeutic approaches to treating and attempting to cure the disease and help people who are affected with sickle cell anemia better manage their symptoms. There have also been several great scientists that dedicated a lot of research to help find a cure for sickle cell anemia.