Discovery Of Nonsteroidal Anti Inflammatory Drugs ( Nsaid )

In the last decade, the number of prescriptions for antibiotics has increases. Even though, antibiotics are helpful, an excess amount of antibiotics can be dangerous. Quite often antibiotics are wrongly prescribed to cure viruses when they are meant to target bacteria. Antibiotics are a type of medicine that is prone to kill microorganisms, or bacteria. By examining the PBS documentary Hunting the Nightmare Bacteria and the article “U.S. government taps GlaxoSmithKline for New Antibiotics” by Ben Hirschler as well as a few other articles can help depict the problem that is of doctors prescribing antibiotics wrongly or excessively, which can led to becoming harmful to the body.

Adverse reactions to drugs are common and almost any drug can cause an adverse reaction.

You don 't come cross anaphylactic shock often, but you still have to be aware. Other severe adverse reactions that could include a fever and skin blistering; these usually occur within an hour of the medications being administered. Sometimes adverse reactions can develop over a few weeks, they may cause damage to the kidneys or liver. If adverse reactions are not treated they could be fatal. When individuals experience adverse reactions to medicines my workplace policy is to inform the GP and explaining in detail the adverse reactions, the staff member will then inform the individual/ team. GP advise and guidance will then determine if the medication is to be stopped. If the reactions are so serious then an ambulance should be called my responsibility is that I have duty to continue to observe the individual and monitor their vitals, speaking to them and looking at any changes, so as to ensure that the individual is not deteriorating. All adverse reactions and following advice given, must be recorded in full in the individual’s clinical note and referenced in their daily report also MAR’s chart. 4.

In most cases the reactions are mild and if they do occur then first-hand you should consult the medicine box/bottle/DOMAR where it will state any possible side effects on the leaflet or possibly on the main label ir you see on some pain medication ‘’Caution-May make sleepy do not operate heavy machinery’’ etc.

The health issues listed here are just a glance at what this drug can do to one’s health.

Prescription and over-the-counter drug use in America has increased steeply over the past fifty years. This is a cause for concern. Too often, these medications only treat the symptoms and not the underlying cause of the disease. And they all come with dangerous side effects. Adverse drug reactions are America’s fourth leading cause of death. Do not assume that OTC medications are safe. They can cause serious adverse reactions on their own and also interact with prescribed drugs to increase risk.

Aspartame has now been on the market for many years and most people seemingly haven’t had adverse reactions. Or have they? Russell L. Blaylock, M.D. warns that many people don’t notice of the serious symptoms because “they’re more resistant to the obvious toxic effects, but they’re still getting very subtle toxic effects that over many years is going to produce obvious disease in those persons.” However, some people have had more direct, severe reactions. For example, FDA officials have estimated that only 1% of toxic reactions are likely to get reported and the agency received reports of 7,000 toxic reactions with aspartame from 1982 until 1995. In fact, there were likely more official reports of toxicity, but we can’t be sure to the extent. After all, Congress found out in 1987 that the FDA had been transferring aspartame toxicity calls to the AIDS Hotline.

The drug Meloxicam is a Non-steroidal anti-inflammatory that has a variety of uses. I will discuss three aspects of the drug. What conditions the drug is used to treat, how the drug is metabolised in the body and other drugs in the same class as Meloxicam.

The use of lamotrigine is associated with several adverse effects such as headaches, nausea, fatigue, ataxia, fever, aseptic meningitis, diplopia, blurred vision, insomnia, nightmares, xerostomia, abdominal pain, painful mouth sores , muscle pain, yellowing of the skin and eyes, restlessness, weight loss, suicidal ideation and mood alternation (22,65,68). However, the most serious adverse effect associated with lamotrigine is a life threating skin rash including Steven-Johnson syndrome and toxic epidermal necrolysis (17,22,66,67).

Adverse reactions to this medication are migraine, speech disorders, rhinitis, sinusitis, hyperglycemia, elevated liver function, elevated serum creatinine level, pancytopenia, bronchitis, dyspnea, toxic epidermal necrolysis, anaphylaxis, elevated creatine kinase, generalized pain, and infection. Nursing considerations with this medication is to have the patient swallow the whole tablet and not to chew. Watch for aspiration while watching the patient take the medication. Educate the patient about the medication and inform them to notify a physician if bleeding

Ibuprofen and Acetaminophen are synthetic mixes created to treat a collection of agony conditions. Ibuprofen can be utilized as a torment executioner and lessens irritation. The historical backdrop of ibuprofen can be followed back to 400BC times when Hippocrates utilized the willow leaf tea as a torment reliever for ladies amid labor. In 1763 Revererend Edward Stone uses willow bark to treat rheumatic fever. It wasn't until 1823 when the dynamic fixing, salicin, is separated from willow. The dynamic fixing was likewise found in 1838 by Swiss and German analysts in meadowsweet bloom. French researchers in 1853 makes salicylic corrosive from salicin. In any case, they understood an annoyed stomach is an unanticipated symptom of ingesting salicylic

Vincristine fits into a collection of drugs known as antineoplastic or cytotoxic mediators. They may also be known as chemotherapy drugs. Common adverse reactions of vincristine sulfate injection include nausea, vomiting, weight loss, diarrhoea, bloating, stomach/abdominal pain or cramps, mouth sores, dizziness, headache, hair loss, constipation, loss of appetite, changes in sense of taste, and numbness and tingling in the hands and feet. Vincristine Sulfate Injection can provisionally lower the quantity of white blood cells in your blood, increasing the chances of infection. There will also be an impact on the number of platelets which may decrease, causing complications in the blood clotting. However, there are precautions you can adhere

1. In many of these cases the drug spread to other areas of the body causing severe adverse reactions such as respiratory failure which lead to death.

Drug research is connected to a range of academic studies such as biology, pharmacology, medicinal chemistry and toxicology. Pharmaceutical researchers can design novel therapeutic drugs based on these studies above. The invention of new drug can be divided by function into two stages: drug discovery and drug development. Drug discovery is the process by which a new drug candidate is found and identified. Distinctively, bringing a new drug candidate to the market through clinical trials is called drug development. The first part of this essay provides an overview of drug discovery and pre-clinical research and development

This report presents the synthesis of Aspirin (acetylsalicylic acid), as the product of the reaction of salicylic acid with ethanoic anhydride under acidic conditions. Aspirin was purified through recrystallisation by vacuum filtration, followed by desiccation of the Aspirin crystal over silica gel. The percentage yield was calculated as 44.89% and a sample of Aspirin was analysed using infra-red spectroscopy and compared to the spectrum of pure Aspirin, this served as an introduction to the identification of functional groups in organic compounds. The melting point was calculated using an IA9000M apparatus and recorded to be 35.2°C, which was slightly below the melting point of pure Aspirin; known to be between 138-140°C. Both IR spectroscopy and melting point measurement were used verify the purity of synthetic Aspirin made, which proved to be fairly pure under these laboratory conditions.