Disease Paper

Surprisingly, the sun-kissed tanned skin is what most younger whiter complexions are eagerly trying to desire; despite the risk of artificial tanning that could cause to a person’s health, but the rate of people using a tanning salon is still rising. In America, there are 30 million white females from ages 16 to 29 years old that are fascinated in indoor tanning (Becirevic, Amel et al, 2017). As the rate of tanning bed users rises the melanoma incident has also increased. Melanoma risk is associated with artificial tanning for a very long period of exposure to the ultraviolet radiation which skin problem can occur later in life. People used artificial tanning as it gives very quick result for a brief period and the fewest number of sessions

Humoral and cellular autoimmunity play a huge role in the appearance of vitiligo. Studies have found that are some major key things that play into this disease developing such as oxidative stress damage, autotoxicity, and neurohumoral

The goals and side effects such irritation within treatment field, dry or moist peeling, possible blistering, telangiectasis, and hyperpigmentation of area were discussed. The early onset of these symptoms due to the combination of the treatments were also reviewed with the patient.

Exposure to Ultraviolet (UV) light, Moles, Fair skin, freckling, and light hair, Family history of melanoma

Vitiligo is a common dermatological disorder characterized by acquired, idiopathic, progressive, circumscribed hypomelanosis of the skin and hair, with total absence of melanocytes microscopically.[1] Various physiological, biochemical, histochemical and enzymatic studies have been done to find out the cause of the disease.[2] Genes certainly play a role in all aspects of vitiligo pathogenesis, even response to environmental triggers, and so genetics really should not be separated out as a distinct phenomenon. [3],[4] In the past few years, studies of the genetic epidemiology of generalized vitiligo have led to the recognition that vitiligo is part of a broader, genetically determined, autoimmune, and auto inflammatory diathesis. [3],[5] The pathogenesis of this disorder is uncertain, but it appears to be dependent on the interaction of genetic, immunological, and neurological

In the present study, the epidermal and dermal H-score of LXR-α and its epidermal nucleocytoplasmic expression in lesional skin were higher than in non lesional skin which was higher than in control skin. This goes with Kumar et al. (2010) demonstrated the expression of LXR-α was significantly higher in perilesional skin as compared to the normal skin of vitiligo patients [10].While the cytoplasmic expression of LXR-α was higher in the control skin in comparison with lesional and non lesional skin. This can be explained by the suggestion of Hu et al. who supposed that the cytoplasmic fraction of LXRα is in inactive form [19].

Melasma Treatment Options that Work Melasma is a common skin condition that causes skin discoloration on the face. Statistics from the American Academy of Dermatology show that the disease affects more than 6 million Americans. Of those afflicted by the condition, 90% are women.

Vitiligo is a skin disease where an individual loses their pigmentation when the pigment producing cells are attacked and destroyed (AOCD, n.d.). Vitiligo is also known to be an auto-immune disorder where certain white blood cells direct the destruction of the melanocyte (AOCD, n.d.). Melanocytes are cells that give us our skin and hair color (AAOD, n.d.). Vitiligo affects any individual no matter their ethnic origin or sex. Individuals often notice that they have the skin disease before they reached the age of 20 which is often notice on individuals with darker skin. Common areas that vitiligo would normally start would be on an individual’s hands, feet, or face (AOCD, n.d.).

Vitiligo is a persistent dermatological condition in which patches of the skin become depigmented. Affected areas lose their natural color and appear noticeably pale. Vitiligo treatment helps alleviate the stigma felt by many people affected by this condition. There is no permanent cure, but cosmetic remedies help many people improve their appearance and feel better about themselves.

There is not physical harm that results when skin color changes. The most common thing that occurs to most people is a sense of embarrassment. This is why some people try to maintain a dark tan that might actually be compounding the problem. Home remedies for melasma will be a much better option.

According to, Le Poole and Van den Wijngaard, vitiligo is a dermatological disorder characterized by destruction of melanocytes and loss of pigmentation. Generalized vitiligo or non-segmental vitiligo (NSV) is characterized by white patches, often symmetrical, that usually increase in size with time, corresponding to a substantial loss of functioning epidermal and in some cases hair follicle melanocytes. According to a study done in 1983 by Naughton, Eisinger, and Bystryn, it affects approximately 500,000 persons in the United States. There aren’t many treatment options at the moment but it has recently come to light that the use of narrow-band ultraviolet (UV) B therapy has had successful results, as well as the use of topical corticosteroids.

When melanocytes become abnormal and grow uncontrollably, they invade surrounding tissues and this is how melanoma develops. Melanoma can grow anywhere on the body bit it is most often occurs on the upper back of men and mostly on a women’s legs. Skin cells develop in a controlled and orderly way, healthy new cells then they push the older cells toward the skin's surface, where they die and eventually fall off. When some of the cells develop the DNA is damaged and new cells may begin to grow out of control, eventually form a mass of cancerous cells. Melanoma’s main cause is a combination of environmental and genetic factors. The experiment was carried out to show that doctors believe exposure to ultraviolet (UV) radiation from the sun and

Skin pigmentation disorders are often caused by sunlight, it causes an increase in the production of cells known as melanocytes that increase melanin in the skin, thus turning the skin darker. These dark skin patches are known as brown spots, age spots, dark spots, sun spots and liver spots.

Like Dr. Morgan said, the reason people get vitiligo is unknown. Even though a person can get it at any time in their life, people usually get it between the ages of 10 and 30. It does not matter whether you are a female or a male or your race; anybody can contract it. At the moment it’s believed that a person cannot be born with it. For vitiligo to be diagnosed, a doctor needs a precise history of illnesses the patient may have had, family history and scrutiny of a characteristic lesions. “ There is no clear pattern of inheritance and no one yet knows which (if any) gene or group of genes is responsible for the condition in humans”, said Dr. Morgan. In an interview with talk show host Oprah Winfrey in 1993, Michael said, “ It’s in my family, my father said it’s on his side. I can’t control it, I don’t understand, I mean, it makes me very sad”. Skin disorders like tinea versicolor need to be excluded. Mostly doctors diagnose by observation. The loss of pigmentation is more noticeable in people with darker skin. The doctor can order a skin biopsy to make sure the patient does not have another disease that is not vitiligo. In some cases, the doctor can suggest the patient get an eye examination to make sure they do not have uveitis ( inflammation of part of the eye), which can be associated with vitiligo. This disease can be linked with

Sometimes, our skin can deal us a hard lot of luck. Skin conditions are a lifelong commitment that none of us ever agreed to, but that we’re stuck with for the foreseeable future. Mesalma is a particularly nasty one, causing hyperpigmentation that makes the skin go a nasty, browny-grey color. If you’re living with it right now, you know what I’m talking about. Whether you’ve had it since birth or it’s just recently developed and you just went on a frantic Google trip, you’ll be happy to know that there are treatments for mesalma out there. But before we get onto that, let’s go for a little trip down memory lane and get you all clued up on this common skin condition.