Disease Pathophysiology And Treatment Of Diabetes Mellitus

1464 Words Sep 27th, 2015 6 Pages
Disease Pathophysiology and Treatment of Type 1 Diabetes Mellitus
Rogelio Gonzales
University of Texas Rio Grande Valley

1. Introduction “Diabetes mellitus, by far the most common of all endocrine disorders, is one of the foremost public health concerns confronting the world today. Over 23 million individuals in the United States, or 8% of the population, have diabetes. An estimated 17.5 million have been diagnosed, but 5.5 million (nearly one fourth) are unaware they have the disease” (Nelms, Sucher, Lacey, & Roth, 2011). The prevalence of Type 1 diabetes mellitus in the U.S. is staggering, and in today’s society these estimated figures do not seem to be declining. Furthermore not only is it affecting the U.S., but also many other counties have been experiencing this global pandemic (Valencia, Bougnères, & Valleron, 2015).
The cause of type 1 diabetes mellitus is not completely understood. The fact that some cases of type 1 diabetics are idiopathic in origin could be a contributing factor to the mismanagement of this disease. However, what we do know is that this disease is an immune mediated disorder. In addition, most cases of type 1 diabetes are usually diagnosed at an early age due its apparent signs and symptoms. Although these cases are easily identified, this specific type of diabetes makes up only 5% to 10% of the individuals diagnosed. (Nelms, Sucher, Lacey, & Roth, 2011)

2. Etiology The pancreas produces two main hormones, insulin and glucagon. Insulin…
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