Disease Resistance and the Immune Modulatory Effects on Nile Tilapia
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Numerous studies have assessed the feasibility and effectiveness of supplementing aquafeeds with a variety of potentially probiotic bacteria, but probably the most well documented are LAB . Among LAB, lactobacilli strains have been the focus of much interest. Since, the immune system modulation strongly dependent on the metabolites they produce, such as proteolysis, could release peptides that may (or may not) interact with immune cells to induce distinct immunomodulatory response . Though only few strains of lactic acid bacteria (LAB), especially Lactobacillus, have been isolated from marine environments, their unique characteristics have proved that there is clear potential to use them as probiotics with advanced health benefits .
To the best of our knowledge, the present investigation was the first report on disease resistance and the immune modulatory effects on Nile Tilapia using dietary supplemented with marine LAB. Therefore, the present work selected the most promising marine LAB isolated from Egyptian marine samples and evaluated its effect(s) on innate immunity and disease resistance of Nile Tilapia fish during 50 days feeding trial.
Based on the physiological characteristics, using API 50 CHL, it is pointed out that the selected isolate R1 is Lactobacillus plantarum. Furthermore, antimicrobial activities induced by Lb. plantarum against the fish pathogen, A. hydrophila, could be attributed to the fact that lactobacillus bacteria can be stimulated to