Clinical Question: Does HPV vaccination in MSM significantly prevent anogenital neoplasia occurrence and recurrence compared to not being vaccinated? Introduction Anogenital cancer (rectal, anal, anal canal, anorectum, penis and other genital) rates are on the rise with 27,660 estimated new male cases and 710 estimated male deaths in the United States last year alone.1 Currently, the Center for Disease Control (CDC) recommends vaccination in the men who have sex with men (MSM) population up to age 26 if they had not received it when they were younger.2 There are no current recommendations for this population who are greater than age 26 who have not previously received the vaccine. As age of an individual and number of lifetime sexual partners increases, the risk of developing anal cancer also increases. Men who have had >15 sexual partners during their lifetime show an increase in risk of developing anal cancer (OR=5.3; 95% CI, 2.4-12.0). Additionally, men who practice receptive anal intercourse is independently related to an increased risk of developing anal cancer (OR=6.8; 95% CI 1.4-33.8).3 These findings suggest that the MSM population, especially the aging MSM population, is a high-risk group that could benefit from vaccination protecting against the strains of Human Papiloma Virus (HPV) that are associated with cancer development. This growing need is addressed through extensive research of relevant literature answering the question “Does HPV vaccination in MSM
What is the Human Papillomavirus? Commonly known as HPV, it is an infection that spreads through sexual contact. There are over one hundred different types of HPV; several types cause genital warts, while other high risk strands can lead to cancer of the cervix, anus, vagina, and penis. Because HPV is often asymptomatic, many people are unaware of their infection status, and thus, their potential for transmitting the virus to a sexual partner. The significance of the Human Papillomavirus is that fifty percent of Americans who are sexually active will contract it within their lives, and at any given point there are twenty million Americans already infected with it (“By the numbers: HPV Vaccine”).
The human papillomavirus (HPV) is a sexually transmitted disease (STD) that is very common throughout the United States and worldwide (World Health Organization (WHO), 2016). There are over 100 different forms of the virus with 13 of these types being capable of causing cancer (WHO, 2016). HPV can lead to the development of serious health problems. Theses health problems are especially an issue for adolescent women due to the highly increasing STD rates among this age group (Kostas-Polston, Johnson-Mallard & Berman, 2012). There is a vaccine for many of the common types of HPV, however, many parents are refusing to vaccinate their daughters for various reasons. With the rising cases of STDs, less birth
In addition, the immune system of most women will usually suppress or eliminate HPVs. This is very important because only an ongoing persistent infection has the potential to lead to cervical cancer (HPV). Eleven thousand cases of this kind of cancer were confirmed in 2007 in the United States; the amount undiagnosed is still unclear but believed to be in the tens of thousands. But to give some perspective of the problem you need to understand its effects on a global level. On the world wide scale cervical cancer strikes nearly half a million women each year, claiming more than a quarter of a million lives. “High risk” HPV types 16 and 18 are implicated in Seventy percent of cervical cancers and are hence selected for vaccine targets (The HPV).
Human papillomavirus (HPV) is a killer. It is an awful disease that is the culprit of many deaths each year. We have the means for its prevention, yet HPV vaccination for girls is a controversial topic to some. This controversy carries over to the current question on whether or not males should also be vaccinated. The issue is starting to play a huge role in the media; Fox news recently broadcasted a story on male HPV vaccinations. This story makes clear the benefits that would come from vaccinating males, including a statement from the Center for Disease Control that, “The HPV vaccine will afford protection against certain HPV-related conditions and cancers in males, and vaccination of males with HPV may also provide indirect protection
HPV is by far the most common sexually transmitted infection in the United States. Per the Centers for Disease Control and Prevention (CDC), 50 percent of all sexually active men and women will get it at some point in their lives, and 20 million already have it. A vaccine is available that prevents 70% of cervical cancers that arise from sexual intercourse. The human papillomavirus is unknowingly common and is diagnosed in 10,000 women a year, causing 4,000 deaths per year (“HPV Question and Answers”). If we take the responsibility to vaccinate young girls and boys, to be safe, we can eliminate many unnecessary deaths. This vaccine is a great discovery that should be put to good use, the HPV vaccine should be mandated in young teens everywhere.
Current evidence-based practice involves providing vaccinations as they protect the child for a lifetime (Joanna Briggs Foundation, 2009). Secondary prevention involves early screening for cervical cancer related to the HPV infection. Early screening for cervical cancer is crucial as cervical with women over the age of 30 according to evidence-based practice as the rates of HPV are higher (Agency for Healthcare Research and Quality, 2011). Tertiary prevention focuses on minimizing the effects of HPV. For example, mental health programs assist the individual with coping with the diagnosis of HPV. These levels of prevention are crucial for assisting those with the diagnosis of HPV and the community health nurse has an important role in educating these individuals to prevent further health
Prophylactic vaccination against high risk human papilloma virus 16 and 18 represents an exciting means of protection against HPV related malignancy. However, this strategy alone, even if there is a level of cross protection against other oncogenic viruses, cannot completely prevent cervical cancer. In some countries cervical screening programs have reduced the incidence of invasive cervical cancer by up to 80 percent although this decline has now reached a plateau with current cancers occurring in patients who have failed to attend for screening or where the sensitivity of the tests have proved inadequate. Cervical screening is inevitably associated with significant anxiety for the many women who require investigation and treatment following abnormal cervical cytology. However, it is vitally important to stress the need for continued cervical screening to complement vaccination in order to optimize prevention in vaccines and prevent cervical cancer in older women where the value of vaccination is currently unclear. It is likely that vaccination will ultimately change the natural history of HPV disease by reducing the influence of the highly oncogenic types HPV 16 and 18. In the long term this is likely to lead to an increase in recommended screening intervals. HPV vaccination may also reduce
Human papillomavirus (HPV) infection is a widespread sexually transmitted infection. Approximately 14 million Americans are infected with HPV each year ("HPV Vaccine for Preteens and Teens,"). HPV also causes several types of cancers, such as vaginal cancer and anal cancer. More than 27,000 women and men are affected by a HPV-related cancer annually ("The Link Between HPV and Cancer,"). The most common HPV cancers for women and men are cervical cancer, and oral cavity and oropharyngeal cancers, respectively. Research has demonstrated that many cancers caused by HPV can be prevented by the HPV vaccine, which is administered in 3 doses over 6 months ("The
I have chosen this paper since one of my goals during the Integrated Practicum was to gain knowledge about cancer prevention and management in the community settings. I believe that this article might increase my understanding about the usage of HPV Vaccines in prevention of various types of cancer.
For males the following diseases that can be prevented include genital warts, and the following cancers anal, throat, mouth, and penile (CDC, 2016). Cervical cancer from HPV are caused by HPV types 16 and 18 by 70%, anal cancer is caused by HPV type 16 by 95%, and throat and mouth cancer is caused by type 16 by 70% (NIH National Cancer Institute, 2016). Type 16 also causes cancer in the following areas vagina by 65%, vulva by 50%, and penile by 35% (NIH National Cancer Institute,
Almost all cervical carcinomas are caused by Human papillomavirus (HPV). Cervical cancer can be a life-threating disease. However, over recent years the occurrence of cervical cancer has declined as well as the chance of dying from it. A huge contributing factor to this decline is the importance of a regular pap smear. A pap smear can find cervical pre-cancer before it turns into cancer. Recently, a vaccine for HPV, has been on the market, which provides close to a 100% protection against pre-cancer and general warts. HPV and cervical cancer are two disease that are closely related. However, each disease effects not only similar populations, but also different populations, as well as having its own signs and symptoms, detection procedures,
(Attention Getter) The Center for Disease Control reports that 100% of sexually active men and women contract genital HPV
Approximately 500,000 new cases of cervical cancer occur each year worldwide, 260,000 of which are fatal. In the U.S., it is estimated that there were over 9,700 cases of cervical cancer in 2006, and of these 3,700 resulted in deaths”. Vaccinations are one of the most successful public health approaches to preventing and controlling infectious diseases. According to the CDC Advisory Committee on Immunization Practices the vaccine has been proven to be virtually 100% effective against the two types of HPV that are responsible for some 70% of cervical cancers.
The HPV vaccine is cancer prevention. Over thousands of cases of HPV cancers are detected every year in men and women. The HPV vaccination is important because it can prevent these cancers. The United States Food and Drug Administration approved this vaccine and it is one hundred percent safe. This vaccine is preventive care for the second leading cancer in women. It has been proven to be one hundred percent effective in prevention of cervical cancer, but the vaccine must be given to children between the age of 11 -17 before they become sexually active. After the age seventeen with young women most become sexually active and receive their first pap smear from their gynecologist, receiving the vaccine at this point is not as effective in prevention of cancers. Another benefit of receiving the vaccine during adolescent, is it supports people who may not have the medical knowledge or access to regular medical services.
The Human papillomavirus (HPV) is the virus responsible for cervical cancer. It is one the most common viral sexually transmitted infections. A vaccine was approved in 2006 that is effective in preventing the types of HPV responsible for 70% of cervical cancers and 90% of genital warts. Proposals for routine and mandatory HPV vaccination of girls have become sources of controversy for parents of school-aged youth, legislators, members of the medical community, and the public at large (Cooper et al. 2010).