Dr. Tb And New Rapid Diagnostics

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In its 2014 Global Tuberculosis Report, the WHO stresses DR-TB poses a major threat to the control of TB worldwide.
Currently, an estimated 3.5% of new cases of TB and 20.5% of previously treated cases have MDR-TB. In 2013 there were an estimated 480 000 new cases of MDR-TB and 210 000 deaths. On average 9% of people with MDR-TB have XDR-TB.
Although there has been progress in the detection of DR-TB through the use of new rapid diagnostics, gaps between diagnosis and treatment have widened in several countries recently.
In terms of treatment, only five of 27 high MDR-TB burden countries achieved a treatment success rate of ≥70%. Health system weaknesses, lack of effective regimens and other treatment challenges are responsible for the
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I will include recommendations to address the aforementioned priorities.

Definition, Transmission and Treatment
The two forms of DR-TB are defined as follows: “Multidrug-resistant tuberculosis (MDR TB) is a form of tuberculosis that is resistant to two or more of the primary drugs (isoniazid and rifampin) used for the treatment of tuberculosis; and Extensively drug-resistant tuberculosis (XDR TB) is tuberculosis that is resistant to at least isoniazid and rifampin among the first-line anti-TB drugs and is resistant to any fluoroquinolone and at least one of the three second-line injectable drugs.” XDR is thus an evolution of MDR-TB. The two main causes of DR-TB in an individual are, first, through the interruption of antibiotic treatment during regular tuberculosis therapy whereby the amount of drug in the body is reduced to levels insufficient to kill the bacteria. The interruption is most commonly caused by: “the patient choosing not to complete the full course of treatment; a rupture in the patient’s drug supply, poor drug prescription – wrong drug, dose or length of treatment; and/or poor quality of drugs.” Resistance to one or several forms of treatment then occurs when the bacteria develops the ability to withstand the antibiotic attack. The second cause of DR-TB infection occurs when this resistance, subsequently passed on to the bacteria’s offspring, creates of a whole strain of resistant bacteria that can then be spread from one person
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