Drug Cocaine Essay

What is Cocaine? Cocaine is the most powerful stimulant of natural origin. It is taken from the leaves of the coca plant which is native to the Andean highlands of South America. It is a potent brain stimulant and one of the most addictive drugs. In ancient times, South American natives used coca for religious and medicinal purposes. The natives took advantage of cocaine’s stimulant properties to fight fatigue and hunger or to enhance endurance.

American physicians begin to use cocaine in medical practices. Cocaine was identified as a drug that depresses the central nervous system; however it had the exact opposite affect. The only general anesthetics available to physicians were chloroform and ether. These anesthetics would induce retching or vomit and did little for pain. Operations that required precision and detail

The nasal route has been extensively used for topical treatments in the past, for example, in the treatment of rhinitis with antihistamines. However, due to the appealing drug absorption potential of the nasal mucosa, intranasal administration for the systemic delivery of drugs has grown in popularity, allowing it to be considered as an alternative parenteral route of administration 11. The nasal mucosa consists of pseudostratified columnar epithelium that lies on top of a highly vascularised basement membrane. The columnar cell surface possesses microvilli which extensively aid systemic absorption through a greatly increased surface area 5. The highly vascularised mucosa plays a significant role in systemic absorption as blood flow, and subsequently the concentration gradient across the membrane, has a major influence in the absorption of drugs into the systemic circulation 1. These anatomical aspects, coupled with the nasal cavity’s thin and porous endothelial membrane provide an attractive option for a range of therapeutic applications 5. An example of such an application is the administration of fentanyl. Nasal delivery of fentanyl exhibits a rapid onset of action due to the advantageous nasal anatomy and provides a Tmax of approximately 7 minutes, a

The purpose of the drug is to help treat people with ADHD and Narcolepsy. But of many people who don’t have that, some take it because it increases their ability to focus and

Additionally, you can consume this magical supplement orally, so it is clear that no needles or injections are involved in a

Intramuscular injection is used for the delivery of certain drugs not recommended for other routes of administration, for instance intravenous, oral, or subcutaneous. The intramuscular route offers a faster rate of absorption than the subcutaneous route, and muscle tissue can often hold a larger volume of fluid without discomfort. In contrast, medication injected into muscle tissues is absorbed less rapidly and takes effect more slowly that medication that is injected intravenously. This is favorable

This drug can be taken can be taken by vapor air with an e-cigarette device, snorting it, injecting themselves, smoking it and can be eaten by the

One of the most common drugs use across the nation is Cocaine. Cocaine is classified as a stimulant, which is a group of drugs that cause short-term increase in the mental or physical state. Cocaine has a rich, long history dated back hundreds of years. The native people of South America first used it; they used to chew on it. The natives introduced this drug to the Spaniards when they landed on the continent. This lead to the research of Coca leaves a few hundred years later in Europe. Scientists sought o isolate and name the compound. After it was isolated, it was used as an anesthetic and other medical purposes for a couple of years. It was a useful anesthetic for eye and nasal surgery. However, today, it has very limited anesthetic use.

Some medications can be inserted into the anus (rectally) as a suppository. They may contain active ingredients that are meant to have a local effect.

This novel method of administration involves thin needles which penetrate the stratum corneum to deliver the drug (101). This method is painless and increases

"Cocaine and crack are among the most addictive substances known to modern science, and they have already ruined the lives of millions of Americans" (Morganthau and Miller, 208). Cocaine and crack are both dangerous, harmful drugs. Though pleasurable effects can be obtained from these drugs, the use of crack and cocaine cannot be worth the actual consequences that are inflicted on mind and body. The bad effects of these drugs, by far outweigh the good. Because crack and cocaine are so closely related, it is important to have a firm understanding of both drugs.

Type A (augmented).The reaction results from an exaggeration of the drug’s normal pharmacological actions when given at the

One of the more common addictions that were mentioned is substance or drug addiction. In the medical dictionary substance abuse means, “Excessive use of a potentially addictive substance, especially one that may modify body functions, such as drugs.” The effects of substance abuse can show a discrepancy between physical and psychological effects. Essentially every drug has dissimilar physical effects on the body; they all have an effect on the brain initially in a similar manner. The physical effects of substance abuse includes; respiratory issues, cardiac issues, and even gastrointestinal issues. With these issues, they can get severe enough to lead up to further severe issues such as lung cancer, heart attacks, and kidney or liver damage, which can ultimately lead to death. The psychological effects of this addiction can be just as harmful. The psychological effects included; hypothermia, paranoia, anxiety, violent behavior, hallucinations, depression, loss of interest, loss sense of reality, confusion, flashbacks, sense of distance, and catatonic syndrome (which affects the body’s central

Our study agree with the findings of Mauri MC et al271, Alsen M et al272, Chan TY et al273, Saleem U et al274, Myers JB et al275, Hardwicke C et al276, Kumar S277, Jesslin J et al278 they all reported that benzodiazepine were the most commonly used class of drug for parasuicidal selfpoisoning.

It was suggested that using NLC to carry and delivery domperidone in the buccal cavity could lead to a permeability