Dyslipidemia Research Paper

High cholesterol level is a condition in which the concentration of high density lipids (HDL) specifically cholesterol, has significantly increased in the blood. The build up of these lipids in arteries reduce the supply of blood and hence, oxygen to the heart. Consequently, high cholesterol can lead to stroke or heart attack. Apo – Atorvastatin (Atorvastatin Calcium Tablets) is a medication that helps lower the concentration of cholesterol and other HDL in the blood (Apo-Atorvastatin, 2011) and is manufactured by Apotex Inc.

Hyperlipidemia is the abnormal elevation of any lipoproteins present in the blood. HMG-CoA reductase inhibitors (statins) are commonly used for the treatment of hyperlipidemia, specifically lowering the levels of low-density lipoproteins (LDL) levels. As with most classes of medications, there are many potential side effects. A less common but serious side effect of statins is myopathy. Myopathy is a dose-related side effect that causes skeletal muscle weakness, aching, cramping, pain, stiffness and tightness. The mechanism of this occurrence is unknown, but as will be shown, there is a possible correlation between low vitamin D levels and increased occurrence of statin induced myopathy. The vast numbers of patients on statins results in a high number of patients with statin-induced myopathy throughout the world. This consultation will determine whether vitamin D prophylaxis is safe and effective in the prevention of statin-induced myopathy.

Is elevated cholesterol connected with danger of sort 2, cardiovascular infections and high death rates?

Dietary Factors in Preventing Heart Disease As coronary heart disease is the leading cause of death in the UK, more attention should be paid to preventing the disease. Many patients suffering from heart disease realise that it was mainly caused by their diet. Research has shown that elevated levels of LDL cholesterol are associated with increased risk of heart disease. “ Studies indicate that for every 1% elevation in the bad cholesterol there is a 2% increase in risk of heart disease”

He tells me that his lipids have been elevated, but he is not going to take statin therapy. He has never been prescribed statins. He has not had his levels checked in the last six

Since hyperlipidemia is a common risk factor for cardiovascular disease, adults with a new diagnoses of hyperlipidemia must have their levels kept under control to avoid the devastating outcomes that can arise from having uncontrolled hyperlipidemia. Nonpharmcologic lifestyle changes have been proven to be an effective first-line treatment for hyperlipidemia because of the changes that can be seen in one's total cholesterol, low density proteins, and high density proteins, but the problem arises on how much education is really being given to patients by their providers (Kelly, 2010). Providers in the outpatient setting are well aware of the recommendations in place on the amount of physical exercise that their patients should to be engaging in on a weekly basis, but the issue is how the information is being relayed to the patients.

Atherosclerotic research has recently concentrated on inflammatory cytokines involved in vascular inflammation and how they stimulate the production of endothelial adhesion molecules, which could enter circulation in soluble form, and have the cytokines stimulate the production of messenger cytokine interleukin-6, which incites the liver production of acute-phase reactants such as C-reactive protein to increase. (Packard et al., 2007) In short, cytokines released into the bloodstream have a tendency to bring about an inflammatory response. Researchers have also found that that treatment with lipid-reducing agents is correlated with reduced morbidity and mortality from coronary heart disease and it seems to work near the atherosclerotic lesion, causing stabilization, slowed progression and, in some cases, regression of lesions. (Blankenhorn, 1989) In research it is well know that one human risk factor for atherosclerosis is hypercholesterolemia, which is when total cholesterol and low-density lipoprotein cholesterol are elevated. (Genis et al., 2000) There are more contributors and characteristics of hypercholesterolemia, which include inflammatory responses to oxidative stress,

Cholesterol is a compound chemical that contributes to coronary artery disease, which have a various risk factors which includes poor dieting, smoking, and a family medical history. This disease is very high risks, its one which runs in my family, and family history.

Annual testing for abnormalities in fasting serum cholesterol, triglyceride, HDL cholesterol, and calculated LDL cholesterol levels (ADA, 2008)

(b) With treatment…Statin drugs work by blocking the action of the liver enzyme that is responsible for producing cholesterol. Statins lower LDL cholesterol and total cholesterol levels…at the same time, they lower triglycerides and raise HDL cholesterol levels. Statins may also help to stabilize plaques in the arteries. That makes heart attacks less

The patient was put on a low fat and low cholesterol diet to see if the symptoms would improve and the cholesterol levels would decrease along with some statin medication of Atorvastatin, to help lower the cholesterol within the blood and help to prevent the patient from gaining any associated symptoms that are related with cardiovascular disease. The medication was given as it inhibits HMG-CoA reductase of the enzyme found within the liver that has a huge role in the production of cholesterol. This should show a dramatic reduction in the levels of LDL-C.

The new focus is on “making the healthy choice, the easy choice” (Jost, 2001). Eliminating oils in processed food may help to lessen the obesity level. Many American’s are starting to realize that fresh, lean, sugar free foods are better for their health. Using less salt and eliminating the salt shaker on the table will help to prevent many medical ailments. According, to the article written by Nugun and Merz they state patients with dyslipidemia typically have made poor lifestyle choices related to diet and exercise (Complications of Diabetes and Associated Disorders, Center for Disease Control [CDC],

It would be recommended for ML to start a lipid lowering medication like a statin. The National Heart, Blood and Lung Institute recommends moderate to high intensity statins to people who fall into groups such as diabetic patients with a LDL from 70-189 (Ng, P., Toderika, & Cheng-Lai, 2016). ML would fall into this category and would most likely benefit from starting a medication such as a statin.

Treatment with fibrate drugs acting to decrease free fatty acid production on the peroxisome proliferator-activated receptors (PPARs), specifically PPARα is for both the conditions. The synthetic statin drugs, namely, rosuvastatin and atorvastatin can increase hepatic reuptake of LDL due to increased LDL-receptor expression, resulting in the decrease of LDL

Some folks don’t tolerate cholesterol medicine. Others just don’t want to take it. When we address cholesterol levels naturally, medications become less necessary. If you refuse cholesterol medication it is advisable to take natural, scientifically based steps, to protect your health. Lifestyle changes, clinical nutrition, botanical medicine and other modalities are used to impact this