Ebola Virus: A Big Impact On Human's Health

Ebola was named for a small river near Maridi, Sudan. Since Ebola first appeared in 1967 there have been over 100 cases of Ebola with more than 50% of the patients dying within days of their acute symptoms. Ebola is classified as a biosafety level four agent because of its extreme pathogenicity and the lack of a vaccine or antiviral drug. Ebola virus (Zaire ebolavirus); Sudan virus (Sudan ebolavirus); Taï Forest virus (Taï Forest ebolavirus, formerly Côte d’Ivoire ebolavirus); and Bundibugyo virus (Bundibugyo ebolavirus). The fifth, Reston virus (Reston ebolavirus), has caused disease in nonhuman primates, but not in humans. Ebola has spread between countries starting in Guinea then spreading across land borders to Sierra Leone and Liberia, Nigeria, USA, Senegal and Mali. Ebola has been presented for more than 35 years; however, the largest outbreak began in West Africa in March 2014. Ebola was previously reported in: Nigeria, Senegal, Spain, United States, Mali, and United Kingdom. However, there are no current cases of Ebola in these countries. There were four people who were diagnosed with Ebola in the United States. The two brought ebola into the country while the other two contracted the disease after caring for an Ebola patient in the United States. One man however died from the disease and the other three recovered and are now free of Ebola. Most of these cases were due to people traveling from a country where ebola was present. This outbreak cause severe and

Historically Ebola has had a serious impact on human health and hygiene and still does due to the fact of no vaccine or treatment being discovered, but thanks to improvements in scientific and medical knowledge the virus itself is now controllable.

In 2014 the United States was hit with a force far more deadly and dangerous than many threats received. The ebola virus took the world by storm after it was carried to the United States and spread by people who had visited West Africa. This virus was all the more deadly as it often took hours for any symptoms to occur. In this time the Center for Disease Control spent much time and many resources looking for answers to the many questions they had. Under the time constraint and scrutinizing public, they had to determine what ebola was, what it did and its effects on the general public.

got sick and died. This outbreak infected 318 with a death rate of 93% (Le

Ebola is a serious, deadly disease that has taken too many lives. As of now there are no licensed vaccines for Ebola. However, two prospective vaccines are being tested for safety. Hopefully, we can find an effective vaccine for Ebola and eradicate the

prevention of this subject not only to find a cure for Ebola but for other possible

Our world is currently facing a deadly epidemic which we are calling it a very dangerous viruses that humanity is facing since HIV/AIDS. This virus is called the Ebola hemorrhagic virus. Although there were broadcasts about tentative cures that were conveyed to be prosperous with treating the virus, people all around the world remain to pass on from Ebola. Although this virus is fatal, its signs are occasionally the same as other less dangerous diseases like the flu or a fever. To relax your anxiety about the spreading of the virus, it is very important to know what people are currently dealing with when it comes to this sad epidemic.

A solution to this problem is a new experimental drug called ZMapp has been shown to work on the few humans that it has been tested on and monkeys. ZMapp contains three antibodies that bind to proteins on ebola viruses. In the text Britannica School Ebola it states “In 2015 a drug targeting the Zaire ebolavirus was found to be highly effective in preventing the spread of ebola virus.” This just is one of the few few ways to help fight the ebola virus. An experimental vaccine was tested in 2015 in Guinea. In the article "Final Test Results Confirm Ebola Vaccine Highly Effective." it stated, “The experimental vaccine was given to about 5,800 people last year in Guinea, as the virus was waning. All had some contact with a new Ebola patient. They got the vaccine right away or three weeks later. After a 10-day waiting period, no Ebola cases developed in those immediately vaccinated,23 cases turned up among those with delayed vaccination.” These are two ways our world can help cure ebola and help those with the

The high mortality rate associated with this disease is largely due to the lack of effective preventive vaccines or therapeutic drugs. Despite that the fact that the virus was first discovered in 1976, very little research into developing a vaccine or a treatment to aid in recovery from Ebola has occurred since its discovery (3). Due to the most recent Ebola outbreak in western Africa, researchers are finally tackling the obstacle of finding a cure to ebolavirus. As a result of this, an urgent question that needs to be addressed is why no one has dedicated his or her focus on researching an Ebola vaccine or treatment until the current outbreak. However, there is no single answer to this question. The lack of research and an Ebola vaccine and/or therapeutic drug is the direct effect of the political, social, and ethical injustices that have plagued Africans for numerous decades. This research plans to address these various injustices that have been committed by pharmaceutical companies and the world on the citizens of Africa as well shed light on the virus, its history, and the current vaccine production

Events that took place during this disaster were harmful to many people. Ebola included many details common to other viruses and caused damage to lives that effected the region, but the area has recovered.

Ebolavirus is responsible for highly lethal hemorrhagic fever. Like all viruses, it must reproduce its various components and assemble them in cells in order to reproduce infectious virions and perpetuate itself. To generate infectious Ebolavirus, a viral genome-protein complex called the nucleocapsid (NC) must be produced and transported to the cell surface, incorporated into virions, and then released from cells. To further our understanding of the Ebolavirus life cycle, we expressed the various viral proteins in mammalian cells and examined them ultrastructurally and biochemically. Expression of nucleoprotein alone led to the formation of helical tubes, which likely serve as a core for the NC. The matrix protein VP40 was found to be critical

The Ebola virus has been a widespread problem on Earth for years, especially in Africa. The virus utilizes the NPC1 protein when infecting human cells, which developed Ebola drugs bind to during treatment of Ebola. (DASH Harvard) The Ebola virus uses the NPC1 protein as a decoy to enter lysosomes, although NPC1 usually mediates cholesterol in somatic cells. (Nature Journal) Before selling drugs for Ebola and such diseases, researchers must find out if they interfere with normal processes by binding to wrong proteins or affect the health and function of cells. This study believed that the proteins and genes most similar to the NPC1 would have the most similar expression in the human body. After retrieving the NPC1 amino acid sequence, a BLAST

I think nurses hold a major role in prevention and control the spread of communicable disease, such as the Ebola virus. One of the most important role is educating. Nurses can educate the communities about how to prevent and protect themselves from the disease. But before educating the communities, the nurse needs to familiarize him/herself about the signs and symptoms of Ebola virus and to know how to react in case of a possible or confirmed Ebola case. Nurses also must follow the standard precaution at all time. As equally important roles include collecting data, making nursing diagnoses, investigating and reporting cases, and providing information to the general public.

The Ebola epidemic in 2014-2016 has provided the opportunity for the public to witness the coordinated efforts of many health organizations such as Doctors without Borders, Samaritan’s Purse, World Health organization (WHO), and Centers for Disease Control (CDC). Although WHO focuses on the issues of global health while the CDC attends to the national health issues, these two organizations collaborate when it comes to health crisis, such as the Ebola epidemic. Together, CDC (2016) and WHO (2016), educated the public with similar information on Ebola virus disease: the history, transmission, mortality rate, treatment, prevention, and the latest progress.

Since there is no  preventative treatment for the Ebola virus currently and treatment is only experimental, we have to take careful measures in