Ebola Virus : A Virus

In late 2013, Ebola virus disease (EVD), a deadly and lethal disease, remerged in West Africa spreading to various countries in the region. In humans, the disease is spread through contact with infected bodily fluids leading to haemorrhagic fever (World Health Organization [WHO], 2015). Originating in 1976 in equatorial Africa, past outbreaks with a few hundred cases had been contained within rural, forested areas in Uganda and Congo (Piot, 2012). In 2014, a total of 20, 206 cases and 7,905 deaths were reported to have occurred in up to eight countries worldwide. Of all cases and deaths resulting from the disease, 99.8% occurred in three neighbouring West African countries - Liberia, Sierra Leone and Guinea (WHO, 2014). With a case fatality rate from about 50% to 90%, and the absence of preventative or curative therapies, the Ebola epidemic has led to overall global alarm and further elucidated existing global health disparities that perpetuated the epidemic with these West African countries.

In 2014, Ebola hemorrhagic fever caused an outbreak in West Africa that officially ended in 2016. The Centers for Disease Control and Prevention (CDC) says, “Ebola is a rare and deadly disease caused by infection with one of the Ebola virus species” (“Ebola (Ebola Virus Disease)”). Ebola is caused when a person is in contact with an infected person’s blood or other body fluids. Prevention of contracting the disease include, not touching the dead body of an infected person, not touching body fluids of an infected person, avoiding places infected people are being treated, not touching bats or nonhuman primates

First discovered in the 1970’s, the ebola virus was contained to West Africa (“About Ebola Virus Disease”). Villagers’ diets consisted primarily of the resources readily available. Among these resources were fruit, vegetables, and animals, namely monkeys. Monkeys carried the ebola virus, and when people ate them, without proper cleaning and cooking techniques, they became infected. Ebola, formally known as Zaire Ebola Virus, is transmitted through bodily fluids like saliva, blood, semen, breast milk, mucus, sweat, tears, feces and urine. ("Ebola in West Africa."). Since it was introduced to a third world country, where hygiene is not regarded as important as survival. Without education, protection and segregated sewage, the virus began to spread. In days people were dying after spreading the virus to those closest to them (Waterman). The bodies, though dead, were still harboring the virus and

It is vital to understand deadly viruses and their history in order to prevent future outbreaks. Ebola leaves very few clues after annihilating its victims, so it is incredibly important to analyze those clues. Ebola’s close relationship to monkeys contains key knowledge that could hold the secret to its success. Paying close attention to how Ebola is spreading and mutating could lead researchers to the answer for preventing the contraction of it. Discovering where and how the virus first emerged could lead to Ebola’s end.

Although Ebola caught the world’s attention during the 1995 outbreak in Zaire, the first outbreak occurred in 1976. As the chart below displays, 71% of the people infected died as a result of Ebola during this first outbreak (Bulletin of the World Health Organization, 56 (2): 247-270, 1978). With the current outbreak, this ratio has dramatically decreased as a result of scientific research leading to early detection, but the current infected population is more than 20 times the amount of any previous outbreak and this number continues to grow as no vaccine exists to prevent the disease.

Ebola was first discovered in 1976 near the Ebola River which is now the Democratic Republic of the Congo. There are five identified ebola virus species: Ebola virus (Zaire ebolavirus); Sudan virus (Sudan ebolavirus); Taï Forest virus (Taï Forest ebolavirus); and the Bundibugyo virus (Bundibugyo ebolavirus). The fifth, Reston virus (Reston ebolavirus), causes disease in nonhuman primates. There have been ebola outbreaks in Africa starting in 1976 and lasting until 2016. These outbreaks have occurred as a result of human to human contact with bodily fluids which happens mostly during funerals of the deceased and population migration between countries. Patterns between outbreaks could potentially

Ebola was first recognized in 1976 as the cause of outbreaks of disease in the Democratic Republic of the Congo (then known as Zaire) and in Sudan. About three hundred people in each of the two nations were infected with the virus, resulting in a mortality rate of 88% in Zaire, and 53% in Sudan (Bulletin of the WHO 1978). The disease as it was discovered spread through direct contact of unmans to humans, and then thought, from non-human primates to humans. The epidemic was a result of unsafe and unsanitary hospital practices, and non-sterilized medical equipment. The disease was then contained, however sporadic outbreaks of the Zaire and Sudan Ebola subtypes have risen in the Democratic Republic of the Congo, Gabon, Uganda, and Sudan; one of the latest outbreaks was in the Democratic Republic of the Congo in September of 2007.

Ebola Virus Disease (EVD) is a severe and often fatal disease that can occur in humans and nonhuman primates (such as monkeys and gorillas). The outbreaks of EVD occur predominantly in remote villages in Central and West Africa, near tropical rainforests and where contact with animals is more likely to take place. EVD is transmitted into the human population through close contact with the blood, secretions, organs or other bodily fluids of infected animals (typically nonhuman primates and fruit bats). Once a human is infected it spreads in the community through skin-to-skin contact, direct contact with the bodily fluids of an infected individual, or contact with environments that are contaminated with such fluids. The incubation

As with any infectious disease, whether it originates from a virus, bacterium, or fungi, there is the possibility that it will become an epidemic. For centuries, deadly diseases have threatened to infect and possibly eradicate mankind. The Ebola virus, which causes an extremely fatal hemorrhagic fever, is considered to be one of the most aggressive contagions in the world. The Ebola virus is a member of a family of RNA viruses known as, “Filoviridae” and is composed of multiple distinct subspecies (Bausch et al. 2007). It causes Ebola Virus Disease, a fairly new disease that plagues multiple poor countries within Africa. The virus mainly attacks the lymphatic system, but also severely damages the reproductive and reticuloendothelial systems. The Ebola virus disease causes muscle pain, weakness, limited kidney and liver function and extreme blood loss due to failure of blood clotting.

Ebola is one of the most deadly diseases known to man. The mortality rate of Ebola ranges from 25% to 90% (World Health Organization [WHO], 2014; Centers for Disease Control and Prevention [CDC], 2010; Cowart, 2014). There is no cure for Ebola and no vaccine to prevent its spread (WHO, 2014; CDC, 2010; Cowart, 2014). The virus itself is spreads between organisms through bodily fluids, such as blood and vomit, which are shed by an infected individual (WHO, 2014; CDC, 2010). These fluids typically carry a large viral load, or number of cells that harbor the virus (WHO, 2014; CDC, 2010). The virus is spread when infectious bodily fluids come into contact with mucous membranes (WHO, 2014; CDC, 2010). As such, infection can occur when infectious fluids enter a cut, enter intravenously, or encounter mucous membranes, such as the eyes, nose, or mouth (WHO, 2014; CDC, 2010).

This book took place in the late 1980's, and it is based upon an outbreak of the Ebola virus in a monkey house located in the Washington, D.C. suburb of Reston, Virginia. The first occurrence of an Ebola-like virus (Marburg) takes place in Kenya and a French expatriate named Charles Monet is the first to die from this disease. His terrible and excruciatingly fatal death is described in the most horrific details by Preston. The hospital staff who treated Monet became infected with the virus as well, traveling fast throughout the hospital and carried on more deaths. The Marburg virus was first to explode in a vaccine factory in Germany in 1967. Over the next several chapters, the book describes outbreaks that occurred four years before Monet’s death. Preston then goes on to explaining how

Ebola Virus is a serious transmitted disease by both humans and animals. The disease first appeared in 1976 in 2 simultaneous outbreaks, one in Nzara, Sudan, and the other in Yambuku, Democratic Republic of Congo. The latter occurred in a village near the Ebola River, from which the virus received its name. Ebola Virus is a member of the negative stranded RNA viruses known as filoviruses. There are currently, five different strains of the Ebola Virus including, Zaire (EBOV), Sudan (SUDV), Bundibuguyo (BDBV), Taï Forest (TAFV) and Reston (RESTV). Each of the strains of the virus are very closely related including Reston which only effects animals. Yet, Ebola Zaire is the most highly virulent subtype, often leading to death. All of the different types of the virus are extremely dangerous and often cause death if untreated.

got sick and died. This outbreak infected 318 with a death rate of 93% (Le

Ebola Virus disease (EVD) is a severe and often fatal illness in humans according to the World Health Organisation (WHO) (WHO, 2016). Although initially originating in wild animals it spreads through the human population via human to human transmission of bodily fluids with the average casualty rate being about 50% (WHO, 2016). The key to prevention and control of Ebola outbreaks is through community engagement, safe burials and good health centre prevention measures (WHO, 2015). Two countries will be examined one has experienced multiple cases of Ebola, Sierra Leone, and the other a few cases, the United States of America. The

Ebola Virus Disease (EVD) is a virus transmitted from humans or animals through body fluids. It is transmitted by means of contact with infected blood, mucous membranes, semen and other secretions, therefore being skin lesions and sexual contact significant ways of transmission (Boulton, 2014). As a transmittable disease, progression of the virus had been thought to be linked to higher probabilities of transmission, and therefore safety of persons in contact with infected patients was in question (Yamin et al., 2015). A study conducted in Liberia in 2014 proved such hypothesis to be true and concluded that prompt and accurate isolation of infected patients was a safe method