increasing. In order to evaluate the feasibility of utilizing radiotherapy on Hepatoblastoma (HB), here we conducted a vitro experiment to detect the radiosensitivity of a HB cell line Huh-6. Materials and methods: Cell proliferation, morphology change, cell apoptosis and cell cycle of Huh-6 cells received gradient X-ray irradiation (0 Gy, 1 Gy, 2 Gy, 4 Gy and 8 Gy) were systemically studied with CCK-8 assay, microscopy, Annexin V/7-ADD and PI single staining respectively. Results: The inhibition of proliferation
cancer research uk). Almost two-thirds of all cancer patients receive some form of radiation therapy during the course of treatment predominantly with external-beam photon therapy (ref 40). Proton beam therapy (PBT) is a novel form of external beam radiotherapy technique that utilises positively charged particles in cancer management (ref required). However, the idea of using charged particles for cancer treatment is not new. Robert R. Wilson was a famous American phycist who proposed that, heavy particles
Introduction Treating locally advanced rectal cancer includes radiotherapy (RT), chemotherapy (CT), chemoradiotherapy (CRT), surgery, and subsequent incorporation of molecularly targeted agents. With multimodality treatment, local recurrence rates became less than 10% with the predominant mode of failure is the development of distant metastases (30–35%). Therefore, the addition of induction CT is not aimed to improve local efficacy, but to better control distant disease [1, 2]. The neoadjuvant RT/CRT
THURSDAY, July 21 (HealthDay News) -- Following surgery, a single dose of the cancer drug carboplatin is just as effective, and less toxic, than the standard three weeks of radiation therapy traditionally used to fight stage 1 seminoma, a form of testicular cancer, British researchers report. In addition, treatment with carboplatin results in the development of fewer new seminomas compared with traditional radiation therapy, according to the report in the July 23 issue of The Lancet. For the past
rhabdomyosarcoma (RMS) (65–70% event-free survival rate) [2, 3]. Though EWS and RMS are considered radiosensitive, the proportion of patients whose primary tumors are treated with external-beam radiotherapy (EBRT) alone has steadily declined over the past 30 years [4]. Increased awareness of the late effects of radiotherapy (particularly second malignancies and growth disturbances) and advances in imaging and orthopedic surgery has increased the use of surgical management for these tumors [5]. Due to the fact
leak in Fukushima, Japan due to the massive earthquake and tsunami. Nearly 20,000 people were killed by the devastating earthquake and tsunami. Although there were no deaths connected with the radiation leak, there is much concern over its long-term effects. I was eager to find out how the radiation leak would affect the citizens in that area over a period of time. Radiation injury is interesting to me because I am half Japanese and have relatives living in these areas. The fear of what will happen to
quite sever. This paper will discuss the process of metastasis, the aetiology and pathophysiology of bone metastases, and the changes that occur within bone due to metastatic spread. It will outline bone metastases signs and symptoms, and discuss radiotherapy treatment options based on patient assessments, focussing on supportive and palliative care. Metastatic spread Metastasis of a primary cancer usually involves local and/or direct invasion, intravasation and circulation. Initially a tumour in situ
of tumor metastasis and recurrence. Radiotherapy is an important treatment for malignant tumors, but the development of resistance to radiation often leads to treatment failure. Recent studies have shown that cancer stem cell is a class of radiation resistant cell group, and radiation resistance might be attributable to the presence of cancer stem cells. As a result, the function and meaning of cancer stem cells have received tremendous attention in radiotherapy. The special DNA damage repair ability
Generally, treating locally advanced rectal cancer includes radiotherapy (RT), chemotherapy (CT), chemoradiotherapy (CRT), surgery, and subsequent incorporation of molecularly targeted agents. With multimodality treatment, local recurrence rates became less than 10% with the predominant mode of failure is the development of distant metastases (30–35%). Therefore, the addition of induction CT is not aimed to improve local efficacy, but to better control distant disease [1, 2]. The adjuvant treatment
before invasive cancer is called in Situ, meaning that the early malignancy has not yet become capable of invasion. Thus, ductal carcinoma in Situ is considered a minimal breast cancer (“Breast Cancer-Encyclopedia”). Breast cancer does not have a single cause. Men can get breast cancer but women are 100 times more likely to develop the disease. Eighty percent of breast cancer are found in women over the age of 50. Some women with multiple risk factors never get breast cancer, while women with not