Effectiveness Of An Extraction Process And Purification Process

Aspirin, Caffeine and Salicylamide were extracted from an over-the-counter pain reliever (BC Powder). These components were separated by manipulating their solubilities by adjusting the acidity and basicity of the solution. By doing this, the three components were forced into conjugate acid (or base) forms, causing selective solubility in either an aqueous or organic solvent. These layers were then separated by use of a separation funnel. Once separated, the components extracted were characterized by measuring the melting point and performing a TLC analysis. Also, the recovered aspirin from the first part of the experiment was recrystallized and compared to that of the

Many manufactures release the caffeine content of their products publically, but not always, and new products and flavors are continuously introduced to the market. If quality checks are not performed, manufactures may alter the caffeine and benzoic acid content to suit the demands without public knowledge. To ensure the levels of caffeine and benzoic acid in products do not exceed the established safe limits and to inform the public of the amount of these compounds being consumed, various methods of analysis have been performed. Before the introduction of modern techniques, spectrophotometric methods alone were used to determine concentration of a compound in a mixture.6 The caffeine content in coffee, tea, soft drink, and energy drinks were determined using an immunoassay.7 The caffeine content in mixtures also used to have to be extracted before quantification.8

Caffeine is a wildly use drug in today’s society. Caffeine is a methylated xanthine which acts as a mild central nervous system stimulant (MS & RL, 2001). It is a stimulant which acts upon the central nervous system and increases alertness, wakefulness and restlessness and it increases the release of catecholamine from renal medullar (Fernandez, 2016; Collines, 2007). It is present in many beverages. Caffeine is found in coffee, tea, soft drinks, products containing chocolate (cocoa) and some medication (Collines, 2007). It is used as a cardiac and respiratory stimulant (Collines, 2007).Caffeine is the most frequently ingested pharmacologically active substance in the world (Collines, 2007).

Pure caffeine is a white powder, like what is found in caffeine pills, and is “a plant-based alkaloid which

In the first acid extraction of benzocaine, the compound was dissolved in the organic solvent of dichloromethane. When the mixture was shaken with HCl, benzocaine’s amine group gained a proton and became more soluble in water than dichloromethane. This allowed the newly formed hydrochloric salt to migrate to the aqueous layer. However, the addition of NaOH to the acidic aqueous layer regenerated benzocaine by deprotonation, making it insoluble in the aqueous layer. The precipitation of an ionic salt was therefore recovered by vacuum filtration and had a tested melting point range of 85.1C-87.4C compared to 88C-90C, the literature melting point of benzocaine. The similarity in melting point ranges, but low percent yield of 30.37% proves that the extract was somewhat successful. Lower yields may be the result of spillage performed in the lab. In the second basic extraction, the organic layer now included benzoic acid and benzamide. When treated with NaOH to deprotonate benzoic acid, the newly formed sodium benzoate transitioned to the aqueous layer as a sodium salt. Benzoic acid is regenerated once again after the addition of HCl and became insoluble in the aqueous layer after protonation. Its precipitation was then filtered out for a 65.87% recovery. Compared to its literature melting point of 122.41C, the resulting 120.9C-123.5C melting range of the sample also supports the accuracy of the separation due to its similarities and high percent yield. In conclusion, the usage of base and acid liquid extraction was mostly successful in this experiment because it was able to efficiently and properly isolate the impure mixture into two separate components of benzocaine and benzoic acid. By performing the techniques of extraction and vacuum filtration, the similarities between literature and tested

Caffeine is a mild stimulant that occurs naturally in at least 63 plant species. Caffeine can be found in the leaves, stems, seeds, and roots of these various plants. Caffeine is part of the methylxanthine family. It consists of a xanthine molecule with three methyl groups attached to it. Caffeine can be found in many products like sodas, tea, and coffee, but it also occurs in several other products such as prescription medications, diuretics, and pain relievers. Caffeine’s widespread use and popularity have caused many people to view the substance as an addictive drug. Thus making caffeine the most inexpensive and readily available drug known to man. Then on the other hand there are

5.    Prepare the caffeine solution by dissolving 10g of caffeine tablets in 100ml of water in a beaker. Label the beaker ‘caffeine’. Similarly, add 10g of coffee to 100ml of water in another beaker and label it ‘coffee’.

Caffeine is a natural product that is extracted from the raw fruit of coffee plants over sixty creased alertness. Caffeine gives most people a temporary energy boost and elevates mood..species to be exact. kola nuts, cocoa, yerba maté, guarana berries, coffee beans and teas contain this. Caffeine is rapidly absorbed in about 30 to 60 minutes in our bodies after ingestion. Caffeine is defined as a drug because it stimulates the central nervous system, causing increased alertness. Caffeine gives most people a temporary energy boost and elevates mood.caffeine can also be in things like over the counter medications, and pain relievers.

Components containing caffeine were composed into stock solutions. These solutions were diluted to 1: 10 substance: mobile phase. A stock solution of caffeine was diluted 1:50. A sequence of diluted caffeine solutions were prepared for use as a standard (ppm): 1, 2, 4, and 10. Solutions of acetaminophen, acetylsalicylic acid, and Goody’s Powder were developed to differentiate chromatographic peaks observed. These solutions were subjected to HPLC for examination of the observed peak area and retention time for the set of compounds. Comparison of retention time allowed for the differentiation of peaks observed. The peak area obtained was utilized to determine the relative concentration of caffeine present in Goody’s Powder based on the relationship obtained in the standard. The content of caffeine present in Goody’s Powder by percent weight was identified.

Caffeine has become an integral part of most Americans lives, making it “America's most popular drug by far” (Brian). Most of the country will enjoy a cup of coffee in the morning or a few sodas during the day. Although most of the world’s population consumes caffeine in either coffee, tea, chocolate, energy drinks or sodas, the majority of those people are undereducated about the drug. There are many drawbacks to the drug, but also many benefits.

Caffeine is consumed in abundance worldwide and is extremely prevalent in today’s society. The average adult in the United States consumes around 300mg of coffee a day, making it clear that caffeine is an important part of many people’s lifestyles (Somogyi 1). Almost all of the caffeine that is consumed is in beverages with coffee as the primary source of caffeine in the U.S. (Somogyi 4). Approximately 75% of adults in the United States consume coffee and 58% consume coffee every day (CDBCNet). Chocolate, tea, and some soft drinks also contain caffeine, but generally not as much as coffee (Somogyi 4). Coffee shops are scattered throughout the world, from small local shops to giant chains. With 20,000 coffee shops in

One of the most popular sources of caffeine today is tea. The first tea cup was brewed in 2732 B.C. Dried leaves landed in a boiling cup of water and served to the Chinese Emperor Shen Hung. From China, the idea of tea had spread throughout the world. There is a variety of different types of tea. Lipton, Green Tea, Black Tea, Brewed Tea, and even tea from your favorite beverage places such as Starbucks and Dutch Bros.

Many of us find ourselves drinking a freshly brewed cup of coffee, an ice cold soft drink, a hot cup of tea, or an energy drink whether it be in the morning, afternoon, or in the night but one thing is that they all share a common ingredient: Caffeine

Many of us find ourselves drinking a freshly brewed cup of coffee, an ice-cold soft drink, a hot cup of tea, or an energy drink whether it be in the morning, afternoon, or in the night but one thing is that they all share a common ingredient: Caffeine

Coffee drinking has been apart of our society for thousands of years, and with that came a flock of caffeine crazed people who created an empire of coffee consumption. The constant crave for it has made many successful corporations all over the world for consumers to get their daily fix, such as Starbucks. With hundreds of ways to take your coffee, it has became a universal drink for all ages. For some, it is almost impossible to get through a day without it. The history, businesses, and consumers involved with coffee are the reason caffeinated beverages are such a commonality among the world today.