Effectiveness Of Inhaled Corticosteroids As Needed For Exercise Induced Asthma Among The Adult And Adolescent Population

1135 WordsSep 27, 20145 Pages
Critically Appraised Topic: The effectiveness of inhaled corticosteroids as needed for exercise-induced asthma among the adult and adolescent population. Clinical Scenario: A 25yo male competitive cyclist complains of dyspnea after high intensity or long duration exercising with little to moderate improvement using inhaled short acting beta agonist bronchodilators. He is resistant to using a daily ICS and would like to know if it is possible to take one on a PRN basis. Clinical Question: P: Patients 12yo or older with Exercise Induced Bronchoconstriction “Asthma” (EIB) whom are well controlled symptomatically otherwise I: Inhaled corticosteroids PRN C: Inhaled beta agonist PRN O: Equal or greater effectiveness in controlling symptoms and improving FEV1 Search Terms and Strategy Used: Pubmed.gov was used with the following MeSH terms: • “Asthma, exercise induced” • “Steroids” In addition, the following filter was used to procure 25 results: • “Publications within 5 years” This study was chosen based on the relevance to my PICO. (One time use of an ICS on EIB) The Study: The study induced EIB using eucapnic voluntary hyperpnea (EVH) and tested fall in FEV1 and measurement of other biomarkers associated with EIB; first with a placebo, and then with beclomethasone. This study included seven endurance athletes who trained at least six hours a week, as well as eight untrained persons with mild asthma. All were non-smokers. Characteristics of the subjects include: • No

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