Effects Of Substance Dependence On A Person 's Brain

I grew up being told that addiction runs in the family and that it is inherited. The Etiology and Natural History of Alcoholism article (n.d.) does, in fact, mention that genetics play a role but other factors such as social, psychological, and environmental are also reasons to contribute to addiction. In turn, genes are not solely supported as the only cause for susceptibility. In fact, “[m]ost offspring of an alcoholic parent DO NOT develop alcohol use problems or disorders in their lifetime.” (Module 2: Etiology and Natural History of Alcoholism, n.d.)

There are many models and theories which attempt to explain the causes of substance misuse and dependence. They range from those which highlight the importance of genetic and biological factors to those which stress social and psychological factors and those which may consider the ‘blame’ to be that of the dependent individual (Rassool 2009).

Addictions are a diverse set of common and complex diseases that are to some extent tied together by shared genetic and environmental factors. Addiction includes alcohol use disorders, cannabis and cocaine use disorders, nicotine dependence, as well as non-substance–related behaviors. Both genetic and environmental variables contribute to the use and abuse of addictive substances, which may eventually lead to addiction.

Genetic factors, such as having a family history of drug abuse, has a major influence on the likelihood that someone will fall into a cycle of drug abuse and addiction (Volkow, 2007; Horvath et al., 2013). From a biological perspective, we address issues by attending to the underlying biological cause. Since we know that addiction can be influenced by chemical changes in the brain, we can combat it and prevent relapse by restoring brain chemistry through the use of medications, such as those that eliminate the pleasurable effects of drugs, and ideally through total abstinence from drugs (Horvath et al.,

The National Institute on Drug Abuse (NIDA) describes addiction as a, “chronic disease characterized by drug seeking and use that is compulsive, or difficult to control, despite harmful consequences” (“Understanding Drug Use and Addiction,” 2016). Long-term use can effect and change a person’s ability to learn, judge, and make decisions. Stress, memory issues, and behavior problems are also common side effects of extended drug use. There is not one single factor that can determine if a person will become addicted drugs. However, certain risk factors have been identified as predicting higher probabilities of addiction because of a person’s biology, environment, and development. Adolescents who abuse

While scientists are not sure which genes are responsible for addiction, research shows that there is a strong genetic component. Someone with an alcoholic parent is far more likely to become an alcoholic than the average person. This does not mean that the addiction is inevitable, but it does mean that individuals should be careful about substance abuse issues if a family member is

Alcohol is the most commonly abused drug in the United States. Alcohol abuse is defined as a pattern of drinking that results in failure to fulfill responsibilities at work, school, or home; drinking in dangerous situations; having recurring alcohol-related legal problems; and continued use despite having medical, social, family, or interpersonal problems caused by or worsened by drinking (APA, 1994). Approximately fourteen percent of people experience alcohol dependence at some point during their lives (Kessler et al., 1997). Alcohol dependence refers to a more serious kind of alcohol use disorder and involves three or more of the following: tolerance, withdrawal, drinking more over a longer period of time, inability to cut down or stop, spending a great deal of time drinking, and giving up important social, recreational or occupational activities (Cunha, 2014).

The biological factors that reasearchers say might influence addiction are genetic factors. Researchers have contributed genetics as a cause since there is “hereditary biological differences that make some individuals either more or less susceptible to drug dependence than others” (U.S Congress, Office of Technology pg. 6). When there are biological influences involved in addiction, and there is one or more family members that have suffered from addiction there could be the possibility of a genetic deposition for addiction.

This paper was prepared for SOWK 615.01: Substance Abuse & Dependency. Taught by Dr. Susan Schoppelrey.

Alcoholic beverages are served in many restaurants, sold in many stores, and acceptably consumed in many populations. Although alcohol can become a drug of abuse, not many view it that way. According to the National Institute of Alcohol Abuse and Alcoholism (2014), about 7.2% of adults in the United States ages 18 and over have an alcohol use disorder. A variety of environmental and genetic factors contribute to the development of alcohol addiction. The variability in the causes of alcohol addiction generates variability in the response to treatment. However, what is common among all alcohol addictions is the high risk of relapse. This risk is potentially caused by the lasting changes in the brain that occur when voluntary alcohol use becomes an addiction. The neural changes that are a result of an alcohol addiction potentially put a recovered alcoholic at high risk of relapse until these circuits can be erased and replaced with healthier circuits.

Many Americans suffer from addiction: In fact 8 to 10% of people above the age of 12 are addicted to either alcohol or some form of drug. However our efforts to reduce the amount of people suffering from addiction has proven to be inadequate. Research that views addiction as a brain disease has provided us with with more effective means

While the choice to use alcohol and drugs is initially voluntary, alcohol and/or drug addiction arises because the normal functioning of the brain is impaired so that alcoholism and drug addiction become a “chronic relapsing disease of the brain” (National Institute of Drug Abuse, Drugs, Brains and Behavior. The Science of Addiction. 2014, 5). Drugs impact the pathways of the brain by flooding the circuit with dopamine, which disturbs and distorts normal communication between the brain’s neurons. Dopamine is a neurotransmitter present in regions of the brain which regulates movement, emotion, motivation and feelings of pleasure. Over stimulating the system with drugs produces euphoric effects which strongly reinforce the behavior of drug use teaching the user to repeat drug use. Continuing alcohol and drug use despite the adverse consequences of such use results in abusers experiencing some or all of the following symptoms: mental stress, impulsive behavior, anger, disorganized thinking, poor coping skills, inadequate decision making and inflexible cognitive response patterns.

When drinking alcohol, alcoholics know some side effects. What they dont know is how it damages the brain. Brain disease is one of the many side effects. Alcohol also affects the liver, lungs, heart and cells.

Extensive research shows that biological factors such as genes are just the beginning of the underlying causes of addiction. Environmental factors play a huge role. There is a profound mutuality between family circumstances and the extent of drug addiction. One study that I found particularly interesting involved 559 people; all of which were families. “The main family factors of drug addiction, according to the results obtained, are family atmosphere, strength of family ties, sense of family happiness, structure of authority in the family, and alcoholism.” (NCBI.NLM.NIH.GOV) In found that drug addicts come from a family that aggression and ill will are present and family ties are far less decrepit than those where addiction was not. The ease of access to drugs and alcohol also was a determining factor of the addiction equation. What I found most concerning was that in families where the mother was the authoritative figure 54.4% --that’s more than half—addiction was present. Vice versa, in the families that love and affection were evident the children rarely took any

When someone says, “You get that laugh or that smile from your father or your mother.” You don’t always believe them, but in some studies today it is said that if your parents or anyone in your family has a history of a drug addiction those traits in their genes have a decent chance of being passed down to the children causing problems for them later in life. According to the Drugs and Addiction article in the 2009 Addiction Journal, “Family, twin and adoption studies suggest that the heritability of substance use disorders is moderate to