Most natural products are generated from plants because they have the “broadest spectrum of biosynthetic capability”(Lokanatha M. K. Prof). Natural products play a very pivotal role in the identification of compounds that are essential in the treatment of many devastating ailments such as cancer. Vincristine is an example of a lead anti-cancer compound that is derived from plant. Vincristine is from a class of vinca alkaloid that is derived from the plant Catharanthus Roseus. Catharanthus Roseus
Phytonutrients (Lycopene) Abstract Phytonutrients are manufactured in pants where they are in turn utilized by humans to avoid various health issues. The production of these chemicals is often prevalent among plants such as vegetables and fruits. Phytonutrients may be classified into Terpenoids, Alkaloids and Phenolic depending on the chemical structure, phytonutrients are categories into different classes which include; Resveratrol, Epicatechin, Lycopene, and Lutein. Lycopene may be referred to as a bright
Siddha, Ayurveda, Unani and Allopathy use differnt plant species1. Allopathic medicine is a system of medicine that focuses primarily on reacting disease rather than on promoting health. The use of herbal medicine is popular due to toxicity and side effects of allopathic medicines. Cancer is presently responsible for about 25% of all deaths in US and other developed countries. On a yearly basis, 0.5% of the population is diagnosed with cancer. It can be treated with chemotherapy, immunotherapy
Soy Protein: Can It Really Prevent Cancer? Society possesses a natural fear of the disease cancer. Even though this term is common, uncertainty surrounds its meaning. What exactly is cancer? A simple definition for a complicated disease is this: abnormal cell growth. Cancer can develop in just about any part of the body, and as abnormal cells grow, they crowd and destroy healthy tissue. This disease is not infectious, for if it were, a vaccination would have probably been developed
The chemicals in the cannabis, or marijuana plant can cause desired psychological and physical effects on the human body. However, for many years there has been an ongoing debate about the legality of the drug. In the last few years specifically, the issue has become very popular and has received a lot of attention from the media. Citizens, doctors, and politicians have many different views and opinions on whether the drug is dangerous or harmless. Marijuana comes from a natural plant and causes
Pueraria tuberosa is known for its therapeutic potentials in cardiovascular disorders but its effect in angiogenesis not been studied so far. In this study, a computational approach has been applied to elucidate the role of the phytochemicals in inhibition of angiogenesis through modulation of Vascular Endothelial Growth Factor Receptors: VEGFR1 & VEGFR2, major factors responsible for angiogenesis. Metabolite structures retrieved from PubChem and KNApSAcK – 3D databases, were docked using AutoDock4
Limitless replicative potential is an acquired capability of many cancer cells, and it was listed as one of the original hallmarks of cancer [1]. It is mostly achieved by upregulation of telomerase, a reverse transcriptase DNA synthesis enzyme that maintains the telomeres length. Most tumor cells have a high level of telomerase activity but short telomeres due to prior divisions before achieving telomerase-activating malignancies [2]. In contrast, normal progenitor cells and stem cells have relatively
Introduction In 2012 my mother was diagnosed with breast cancer, for the following year and a half I watched my mother undergo multiple surgeries, daily radiation, and a variety of other intensive treatments. Throughout the entire process I watched my mother physically and mentally deteriorate. At the time my knowledge of the disease was minimal and not only was I fearful of my mothers future, but I was also unaware of the physiological functions that would overcome my mothers body eternally. Following
Colorectal cancer is the third most common cancer in the world (World Cancer Research Fund International). Colostomy, chemotherapy, radiotherapy and biological therapy are among the most common treatment for colorectal cancer. These treatments may be used by itself or in combination. One of the most commonly used drugs for the treatment of colorectal cancer is 5-fluorouracil (5-FU). 5-FU is a cell cycle–specific, S-phase–dependent fluorinated pyrimidine analogue (Yim, et al., 2006). Due to its short
chemotherapy of cancer, cachexia in HIV, anorexia, chronic, spasticity in numerous sclerosis and injury of the spinal cord are strong evidences of the medicinal benefits of the plant. For several indications, like pruritus, epilepsy and depression, there is lesser data on the topic. However, methodical evidence for specific indications do not inevitably replicate the definite relaxing potential for a particular disease. Medical studies focusing on cannabinoids or the whole preparation of the plant (whether