cold or influenza and relief of cough(Allen and Popovich 2005)(Allen and Popovich 2005). Dextromethorphan (DXM).scheme 1.(o-3-methoxy- N-methylmorphinan) is a one of the older and popular antitussive drugs that used to treat the cold symptoms that effects centrally at the cough center to raise the threshold for coughing (Goodman 1990, Dale)(Goodman 1990, Dale)(Dale) DXM is also combined with other active ingredients like chloropheniramine and it could abuse or misuse for numbing and hallucinogenic