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Emphysema Lab Report

Satisfactory Essays

The overall goal of my laboratory is to study the mechanism of alveolar type II cell injury in emphysema. The mechanism of this disease pathophysiology is not well known. There is a very limited therapeutic strategy against emphysema. This disease is a primary indication for lung transplantation. However, this also leads to high mortality related to cardiovascular problems. Therefore, our projects are focused on identification of potential novel therapeutic targets and have translational and clinical implications. To our knowledge, my laboratory is the first to isolate primary alveolar type II cells from excess tissue obtained from patients with emphysema. We also obtain tissue from control organ donors whose lungs were not suitable for transplantation

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