preview

Endocrine System Physiology

Good Essays

Lab 28B: Endocrine System Physiology Computer Simulation Introduction The endocrine system is the second greatest control system of the body and has many effects on the tissues and organs. The thyroid gland, which is a part of the endocrine system, releases a hormone that maintains metabolism. This hormone is thyroxine. Thyroxine production is controlled by thyroid stimulating hormone, which is released by the pituitary gland. TSH stimulates the thyroid gland to produce thyroxine. In this experiment, the effects of TSH and thyoxine on metabolic rate are investigated. Estrogen is a hormone produced by the ovaries that helps the uterus to develop. The removal of the ovaries eliminates the source of estrogen and the uterus …show more content…

With TSH Normal Rat Thyroidextomized Rat Hypophysectomized Rat Weight 249.7 244.4 245.8 ml O2 in 1min. 7.5 6.0 7.0 ml O2 in 1 hour 450.0 360.0 420.0 Metabolic Rate 1802.2 1473.0 1708.7 Experiment 5: Hormone Replacement Therapy The uterus of the rat that received injections of estrogen was found to weigh more than that of the rat that received injections of saline. Rat Elapsed Days # Saline injections # Estrogen injections Weight of Uterus Control 7 7 0 .1073 gms Experimental 7 0 7 .6681 gms Experiment 7: Comparing Glucose Levels Before and After Insulin Injection Test Tube Opt Density Glucose Insulin Saline Alloxan 1 normal .62 87 No Yes No 2 alloxan .87 129 No No Yes 3 nor/insulin .62 87 Yes Yes No 4 all/insulin .68 96 Yes No Yes Discussion and Conclusions The results for the baseline metabolic rate were as expected. The metabolic rates of the Tx and the Hypox rat were lower than the metabolic rate of the normal rat. The Tx rat could not produce thyroxine because it had no thyroid gland. The Hypox rat could not produce TSH which stimulates the thyroid to produce thyroxin. The results of the thyroxine metabolic rate were as expected. The injection of thyroxine increased the metabolic rate for all rats. This is understandable as thyroxine is the most important hormone in maintaining metabolism. The injection provided the Tx rat with a source of thyroxine in place

Get Access