Eotaxin-2 Research Paper

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Eotaxin 2 Human

Eotaxin-2, also called MPIF2 & Ckb6, is a novel CC chemokine produced by activated monocytes and T lymphocytes. Eotaxin-2 can selectively chemoattract cells expressing CCR3 including basophils, eosinophils, Th2 T cells, mast cells, as well as certain subgroups of dendritic cells. In addition, Eotaxin-2 is able to inhibit the proliferation of multipotential hematopoietic progenitor cells. The mature protein of Eotaxin-2 consists of 78 amino acids (92 amino acids for the mouse homolog, without C-terminal truncation). Eotaxin-2 is encoded by the CCL24 gene. This gene is located on human chromosome 7 in humans.
Eotaxin-2 is able to function as a chemotactic chemokine for resting t-lymphocytes, and eosinophils. Eotaxin-2 has lower
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