Epidermolysis Bullosa Research Papers

Epidermolysis Bullosa is a genetic disorder that causes the skin to blister even with the slightest force. Epidermolysis Bullosa is found in three different types. Each are caused by different genetic mutations. The most common form of Epidermolysis Bullosa (EB) is Epidermolysis Bullosa simplex (EBS). The less common types of EB

When it comes to treating acne, Asheboro Dermatology & Skin Surgery in West End, NC, has successfully treated patients with Accutane (Isotretinoin), a drug taken orally to help eliminate the redness, scarring and scabbing that’s often associated with the skin condition.

The skin disorders that might results from hereditary, congenital, or acquired pathological processes are ichthyosis, bullous diseases, chronic infections of the skin, dermatitis, hiradenitis suppurativa, genetic photosensitivity disorders, and burns.

Epidermodysplasia verruciformis is one of the most defying horrific rare diseases in the world. Epidermodysplasia verruciformis is also called Lewandowsky-Lutz dysplasia, Lutz-Lewandowsky, and the tree man disease. Epidermodysplasia verruciformis is a recessive hereditary genetic skin disorder. Partial defects in cell-mediated immunity have been demonstrated in this disease. Numerous warts appear on the hands and feet sometimes all of the over the body. Certain people with this condition usually began to show symptoms between the ages of one through twenty. It usually gets worse when they become middle aged. There are different causes, diagnosis, cures, treatments and symptoms to epidermodysplasia verruciformis.

North Dallas Dermatology Associates is a dermatology clinic that is located in Dallas, Texas. North Dallas Dermatology Associates was established in 2000. Their services include cosmetic dermatology, medical dermatology, facial treatments, body contouring and skin tightening, and laser treatments. Their cosmetic dermatology treatments include Botox, Dysport, Cosmetic Fillers, Juvederm Voluma, Sculptra Aesthetic, and more. Their facial treatments include chemical peels, facials, OxyGeneo, microdermabrasion, and MicroNeedling with PRP. Their dermatologists are board-certified.

Epidermolysis Bullosa is a group of inherited connective tissue disease that cause blisters that affects layers of the epidermis (outer layer) and the dermis (inner layer) of the skin. Because the skin of the infected person is so thin and fragile they tend to suffer from skin tears exposing areas that can easily become infected. Epidermolysis Bullosa not only affects the skin but has adverse effect to the inner lining of the mouth, throat and gastrointestinal. Also, in severe cases EB affects the musculoskeletal system. Other areas EB may affect are the urinary tract causing painful urination and the airway resulting in breathing problems.

Epidermolysis Bullosa, also referred as “EB” is a very dangerous disease. It can be inherited from parents. It is a common disorder that can affect your skin.

Developing Personal Skills: it develops personal skills by informing the community of the risk regarding excess sun exposure and what the underlying facts are about skin cancer. The campaign shows ways on how to prevent skin cancer and what you should do in order of prevention. The campaign also shows representations of the appearance of the cancer and how it looks when it is removed as well as providing information on how the incidence of skin cancer within Australia is very high.

Nambudiri (2015) takes the readers on a journey of a boy that had a skin disorder. The boy in the article started noticing lesions on the palms of his hands and soles of his feet, but was not sure what they were. When the lesions turned into papular eruptions, the boy went into urgent care to get inspected. Since the doctor was not sure what the skin disorder was, they took multiple tests, for which all of them came back negative. A skin biopsy finally let the patient know that he had a skin disorder called guttate psoriasis. The disorder was treated with topical steroid cream and topical calcipotriol.

In the last few years, researchers have made great progress in efforts to treat this disease. Common treatments include the use of creams, makeup, and surgery. Creams work to mainly reduce any possible inflammation and some brands even claim that their creams can restore one’s original color. However, many of the advertised creams turn out to have little to no effect and some tend to have side-effects that can result in burns or rashes. Alternatives for cream-based products include getting either skin grafting or blister grafting surgeries. Skin grafting is the process of peeling away small sections of the epidermis layer that has regular pigmentation and placing onto the affected areas. Blister grafting is similar to this process, except it involves the creation of blisters. The blisters are created using a suction and then doctors will remove the top layer of it and transfer it onto the areas with no pigmentation.

In this world many things can happen. One of the most interesting things is that we can get disorders in the womb. These disorders can be good, bad, or it doesn’t change a thing. Most of these disorders all start from a small cell that creates us all. The only thing that’s different is that there was some kind of change in genetics.

Elastoderma is a rare skin disease that creates abnormal structural makeup of elasticity tissue. The mechanism of this disease is excessive accumulation with an unknown cause. This article focuses on a research study conducted using a variety of different methods to identify the difference in skin affected by Elastoderma compared to that of unaffected skin.

After reading this article I gained a wider perspective of the disease, Harlequin Ichthyosis. I already had a vague idea of what the disease was and some of the reasons behind it, but now I know so much more! For example: how the mutations occur in the ABCA12 gene, the reason why the skin grows and developes the way it does, and even the way that they are starting to treat people with these types of rare skin

EB simplex is caused by an autosomal dominant gene mutation which results in faulty keratin protein. Keratin is a protein that provides structure and strength for the skin. Keratin, therefore, acts as a frame for the skin. So when this frame or scaffold is not formed properly the skin tends to fall apart and form blisters. EB Simplex can be localized or generalised. This means that the blisters can be localized, occurring only in the areas where friction or trauma has occurred. While with generalized blistering, blisters can occur all over the body.

In recent news, a 7-year-old boy from Bochum, Germany was diagnosed with a severe form of Junctional Epidermolysis Bullosa (JEB), underwent experimental gene therapy in order to restore fully functional epidermis. JEB is a disorder in which three specific genes – LAMA3, LAMB3 or LAMC2 –encoding laminin-332 in the basement membrane are missing or defective. Specifically, this patient had a homozygous acceptor splice site mutation within intron 14 of LAMB3. JEB inhibits epidermal strength and toughness, leading to blistering, chronic open sore formation, reduced quality of life and increased likelihood of skin cancer. Currently JEB is incurable and over 40% of patients die before 10 years of age.