Epidermolysis Bullosa Simplex Dowling-Meara

Decent Essays
Epidermolysis Bullosa Simplex Dowling-Meara (EBS-DM) falls under the category of a genetic disorder, but it directly affects the epithelium system. The disorder allows the skin to blister very easily. Epidermolysis Bullosa Simplex also makes the skin very fragile and susceptible to open lesions that could then lead to infection. There are two different genes that could cause the disorder, cytokeratin 5 (K5) and cytokeratin 14 (K14). This particular study addresses the increased level of Jun N-terminal kinase (JNK), which in theory, leads to the mutation of the phenotype. Many questions were addressed and answered in the study performed by Martin Wagner, Andrea Trost, Helmut Hintner, Johann W. Bauer, and Kamil Onder. The hypothesis
Get Access