Erdheim-Chester Disease: A Case Study

I always had interest in a clinical research career that serves a large number of people by emphasizing more on research studies by exploring whether a medical strategy, treatment or device is safe and effective for humans. As a graduate in medicine, my strong base in the medical field continually challenged and motivated me to expand my skills in patient care. My coursework has allowed me to develop a keen understanding of how disruption in biological systems can influence one’s health.

| Ensuring therapeutic effects:Continue frequent assessments as described earlier for therapeutic effects.(Blood pressure and pulse should be within normal limits or within parameters set by health care provider. If drug is given for angina and /or dysrhythmias, significant improvement in reports of pain, palpitations, or ECG demonstrates improvement)

EW is a 79 year old male who was admitted with unstable angina, later found to be NSTEMI (Non-ST-Elevation Myocardial Infarction). He also presented with a right lung nodule. EW was admitted on November 16, 2014. The study began on November 21 when EW required a heart-healthy diet education, and it ended on his discharge on November 24.

I have been working as preclinical cancer researcher for many years, have presented my work in several national and international meetings, and have published in several peer-reviewed reputed journals. Despite the fact pre-clinical research and clinical studies are closely associated, yet differ widely; I am excited to take the challenge to conduct clinical research and working on the NIH certification on clinical research design (expected to have it March 2015). I wish to find an approach to bridge the gap between preclinical and clinical studies, investigate ways to improve quality of patient care in active participation of pharmacist, and extend collaboration with interdisciplinary medical teams. I truly feel that PGY-1 program in your institution is well-structured between clinical, research and academia experience, and will greatly support my career

After graduation, I joined the laboratory of Dr. Alan Schechter in the National Institute of Diabetes and Digestive and Kidney Diseases as a NIH Postbaccalaureate Fellow. Although I was ready to pursue doctoral studies after undergraduate, my experience at NIH has prepared me as a person, not only as a student. I have the confidence to weigh choices and make the right decision. Through the guidance of my PI, a clinical mentor, I always hear in the back of my mind “so, how does this relate [to humans]?”. I know how to get stakeholders of a project onboard and keep them on board while on budget and on time. Being open to others’ suggestions and ideas from differing viewpoints and backgrounds, I know how to ask for help, receive help, and

Surgery is an option for some of the issues caused by the disease, but extreme and invasive procedures could be life-threatening to an infant whose lifespan could already be only weeks, or even days. The children that do make it beyond their first year of life require treatments for the various difficulties that are associated with the disease. Problems related to nervous system abnormalities and muscle tone affect the development of the infant’s motor skills. This could result in scoliosis and crossed eyes. Surgical solutions would be limited due to the cardiac health of children with Edward’s disease. Infant’s with Edward’s disease can experience life-long problems, such as constipation which is caused by poor abdominal muscles. Children affected by this disease also have an increased risk for the development of kidney cancer. Other complications the child might require treatment for include seizures, club foot, facial clefts, spina bifida, pneumonias, ear and eye infections, plus many more. Additionally, children with Edward’s disease exhibit severe developmental delays. The parent would have to provide the child with therapy programs and special education early on in the child’s life to make an attempt for the child to reach developmental

Patients locally and from around the world are benefiting from increased research funding, improved patient access to clinical trials, and targeted public-health-based research at the Stritch School of Medicine.

National Institutes of Health Turning Discovery into Health. (2013, March 07). Retrieved March 11, 2013, from National Institutes of Health: http://www.nih.gov

Everyone tells you life isn't easy right? That there’s going to be obstacles that you’ll have to overcome . For me, the biggest obstacle was to change, I couldn’t be another failure in the system, neither be a burden. Many fail to realize that change isn’t bad, is to better yourself on who you really are.

Dr. John Ioannidis is a “meta-researcher” and “one of the world’s foremost experts on the credibility of medical research” and he proposes that the majority, upwards to ninety percent of medical research-studies are untrustworthy. The general population tends to, like Ionnadis once did, believe that everything physicians did was basically right, but his own research into the

Some 400,000 Americans die annually from abnormally fast or irregular heart rhythm, FDA said in announcing approval of the pacemaker device in February 1993. Since this approval, thousands of Americans suffering from irregular heart rhythm are able to live a healthy and happy life thanks to this invention. Because of this small device, symptoms are relieved, lives are longer, and people are able to live life to the fullest. “It’s a big breakthrough,” said David B. Delurgio, an Emory University cardiologist. “It’s not for every heart-failure patient, but a proportion could definitely benefit” (Neergaard). Pacemakers have impacted many important aspects of society including the ability to contribute in the workplace, benefits in the economy of

The scientist I decided to write about is Edward Jenner who lived from 1749-1823. He was born in Berkeley, Gloucestershire, England (The Jenner Institute, 2015). His father was a preacher and died when Edward was five years old, orphaning Edward (Famous Scientists, 2015, Riedel, 2005). He went to school in Wotton-under-Edge and Cirencester (The Jenner Institute, 2015). While he was attending school, his older brother inoculated him for a disease called smallpox when he was only eight years (Adler, 2004, The Jenner Institute, 2015). When Jenner was 14 years old, he studied under a surgeon, Daniel Ludlow, for 7 years where he learned about surgical and medical practice (The Jenner Institute, 2015, Riedel, 2005). In the year 1770 at the age of

Moving forward, Jenkinson and Fotopoulou (2014) summarised the findings since Babinski. First of all, as previously mentioned, the scope of diagnosis has been widely broadened. Secondly,

While working with Portland Cardiology Associates (PCA) I was the primary communicator of FDA clinical trials rules, polices and procedures for new applicants, existing beneficiaries, and referring providers. Upon initial identification and assessment for eligibility, and at each subsequent monthly visit, I interviewed clients from diverse cultures, backgrounds, educational experiences, ethnicities, physical abilities, socio-economic status, ages, genders and identities, and religions and other ideologies. I researched medical records, and acted as a conduit between clients and their providers in order to determine initial and ongoing approval or denial of eligibility. I explained that all medical care associated related with this disease or

The ability for all stakeholders including the CRO, pharmaceutical companies, and the vendors to work in unison increases the chances of achieving successful clinical trials and with high standard clinical data. “Productive teams” take advantage of collective intelligence and diverse competencies of the team members leading to efficient and effective trials with proper risk management, balanced decision making and innovative approaches. They strive towards excellence and achieving results, and do not settle for simply following procedures.