Erythrocyte: Structure & Metabolism

Introduction: The biological membranes are composed of phospholipid bilayers, each phospholipid with hydrophilic heads and hydrophobic tails, and proteins. This arrangement of the proteins and lipids produces a selectively permeable membrane. Many kinds of molecules surround or are contained within

The lipids found in the membrane are known as phospholipids. Phospholipids are fat derivatives in which one fatty acid has been replaced by a phosphate group and one of several nitrogen-containing molecules. The phospholipids’ structure is such that it appears to have a ‘head’ attached to a ‘tail’. The head section of the lipid is made of a glycerol group which is then attached to an ionised

Those cells must receive nutrients and gases in order to undergo the metabolic processes that maintain homeostasis. In paragraph form, explain how you think the nutrients and gases enter the cell. Distinguish between the molecules that can enter by diffusion by simply moving across the membrane and those that must expend energy to cross the cell membrane.

Nearly all animal cells have a nucleus, with the only exception being the red blood cell. The nucleus has two major functions, which are housing the DNA and controlling the cell’s activities. In the centre of the nucleus is the nucleolus. This doesn’t have a membrane, but holds itself together. In the nucleolus, ribosomes are created through the mixture of RNA and proteins. These proteins are originally found in the cytoplasm, outside the nucleus, but they travel through the pores in the nuclear envelope, through the chromatin and into the nucleolus. The structure of the nucleolus allows easy

 The blood cell is made in the bone marrow of a bone and then enters a vein and goes toward to superior vena cava. The blood cell joins millions of other blood cells as well as white blood cells and platelets inside of plasma.

The Journey of a red blood cell begins inside the bone, where the blood cell is made which is the bone marrow. The red blood cells travel around the body within capillaries. Then the deoxygenated red blood cell makes its way to the heart in the vena cava. After the blood cell has made its way through the heart the right atrium (the cell enters the right atrium first) contracts and pushes the blood cell through the tricuspid and into the right ventricle (the parts where the blood cell enters second which is located in the bottom right corner of the heart.) Next the right ventricle again contracts and pushes the blood cell out of the heart through the semi lunar (the section of the heart where the cell enters third). Then finally the deoxygenated

noniceptors to reduce inflammation. They also have some effect on the nervous system to act on

Introduction: Cell membranes contain many different types of molecules which have different roles in the overall structure of the membrane. Phospholipids form a bilayer, which is the basic structure of the membrane. Their non-polar tails form a barrier to most water soluble substances. Membrane proteins serves as channels for transport of metabolites, some act as enzymes or carriers, while some are receptors. Lastly carbohydrate molecules of the membrane are relatively short-chain polysaccharides, which has multiple functions, for example, cell-cell recognition and acting as receptor sites for chemical signals.

In humans/animals, the main cells that store fat for energy are adipocytes. These fat cells are found under the skin, in the abdominal cavity and surround major organs. The fatty tissue is the body’s main means of storing energy for long periods of time. Lipids, like triglycerides are stored in the adipocytes until ready to be used by the body for energy. Fat is broken down through metabolism in the mitochondria of the cell. The triglycerides are broken down into glycerol and 3 fatty acids. The glycerol can be easily converted to glyceraldehyde 3 phosphate, an intermediate of glycolysis. From there it can go through the Krebs Cycle and electron transport chain to make ATP. The 3 fatty acids can be broken

Methemoglobinemia is a hemoglobinopathy where the concentration of methemoglobin in the blood is more than 1% of the total hemoglobin [3]. Normal hemoglobin has a reduced ferrous iron (Fe 2+) while methemoglobin has an oxidized ferric iron (Fe 3+). The change in valence prevents methemoglobin from being able to carry oxygen [4, 9]. There are mechanisms in place to reduce the amount of methemoglobin in the blood [2]. Cytochrome b5-Methemoglobin reductase and nicotinamide adenine dinucleotide phosphate (NADPH) methemoglobin reductase enzymes are responsible for reducing the amount of methemoglobin in the blood [9].

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1 - Describe the normal structure and functioning of cell membranes, and explain how they compare to the membranes relating to a specific abnormality in cystic fibrosis?

and epilim these are all derivatives of a substance called valproic acids these are called

P1 – Describe the microstructure of a typical animal cell and the functions of the main cell components. A typical animal cell is seen as a tiny, three dimensional sac which is in fact made up of many components, each as important as the other. The microstructure of an animal cell was in fact uncovered mainly through the use of both cell fractionation and electron microscopy. Each main component has its own, individual function which helps a cell to function and maintains the cell membrane. The components that I will be describing include the cell membrane, nucleus, cytoplasm, mitochondria, lysosomes, Golgi bodies, centrioles, endoplasmic reticulum (both smooth and rough) and ribosomes.

In my opinion, based on signs and symptoms this patient suffers from hemolytic anemia, characterized by reduction in the number of circulating red blood cells, caused by accelerated destruction and removal of these cells from the bloodstream before their normal lifespan is over. When blood cells die, bone marrow produces more blood cells to replace them, however, in HA, the bone marrow does not make red blood cells fast enough to meet the body's needs. Many diseases, conditions, and factors can cause the body to destroy its red blood cells. This type of anemia can be inherited, where parents passed the gen to the child (hemoglobin defects, enzyme defects, membrane defects) or acquired, meaning it developed overtime (infectious diseases: hepatitis, streptococcus; medications such as acetaminophen, antibiotics, ibuprofen, interferon alfa procainamide). In some cases, the cause of hemolytic anemia can’t be established.