Esomeprazole Magnesium Trihydrate (Nexium): Proton Pump Inhibitor

This condition is characterized by symptoms and complications that result from reflux or back of gastric content into the esophagus that extent also into the oral cavity or even the lungs. Common signs and symptoms of this condition include heartburn( burning/stinging), and does note that radiates to the back such as in the case of Peptic Ulcer Disease (PUD). Furthermore, other symptoms patients may experience are a chronic cough, bronchospasm, chest pain not related to a cardiomyopathy, hoarseness, early satiety, abdominal fullness, bloating with belching. Complications related to this disorder are closely linked to esophageal ulceration, hematemesis, melena, stricture development(Dains, Baumann, & Scheibel,

Belladonna alkaloids is used to treat irritable bowel syndrome (IBS) and intestinal inflammation in combination with other medications. IBS is an invasive gastrointestinal functional bowel disorder, characterized by a recurrent crampy diarrhea and abdominal pain. Belladonna works by decreasing motion of muscles in the intestine and stomach providing them with a mild sedation

     In this article, you are informed about a disease that is occurring more often in our society. It is commonly referred to as “heartburn” but is more appropriately named acid reflux disease or gastroesophageal reflux disease (GERD). Most people suffer from this disease, but think nothing of it. Perhaps they have felt it after a big meal, lying down after eating, during pregnancy, or even when bending over. Most people feel that GERD occurs after eating spicy foods, when in fact the major cause of GERD is fatty foods and the quantity of foods eaten.

GERD is another name for heartburn. There is a backflow of gastric and duodenal content that past the lower esophageal sphincter (LES) into the esophagus. As reflux of gastric acid causes acute epigastric pain after eating a meal. The pain can radiate to the person arm and then chest. The LES usually retains sufficient pressure around the lesser end of the esophagus to close it and prevent reflex. As the sphincter relaxes with each swallow, the food empty into the stomach. High acidity in the stomach triggers irritation and pain as the content enters the esophagus causing reflux esophagitis. In GERD, the sphincter is open, due to incompetent LES pressure or increase pressure within the stomach exceeds LES pressure. The pressure in the stomach propels the content into the esophagus.

GERD disease, commonly referred to as GERD or acid reflux, is a condition in which the liquid content of the stomach regurgitates (backs up or refluxes) into the esophagus. The liquid can inflame and damage the lining (esophagitis) although visible signs of inflammation occur in a minority of patients. The regurgitated liquid usually contains acid and pepsin that are produced by the stomach. (Pepsin is an enzyme that begins the digestion of proteins in the stomach.) The refluxed liquid also may contain bile that has backed-up into the stomach from the duodenum. The first part of the small intestine attached to the stomach. Acid is believed to be the most injurious component of the refluxed liquid.

Commonly known as heartburn or reflux, is a condition where reflux of the gastric content into the oesophagus leads to symptoms which significantly impact a person's quality of life. Gastroesophageal reflux disease gerd is the most prevalent acid related disorder and is associated with significant impairment of health-related quality of life. Gastroesophageal reflux disease gerd occurs when acid and food in the stomach back up into the esophagus.Gerd often occurs when the lower muscle (sphincter) of the esophagus does not close properly. The sphincter normally opens to let food into the stomach. It then closes to keep food and stomach acid in the stomach. If the sphincter does not close properly, stomach acid and food back up (reflux) into the esophagus. The following may increase your risk for gerd. Gerd may be associated with several extra esophageal syndromes such as chronic cough, asthma, laryngitis, oropharyngeal ulceration and dental erosions. Available evidence indicates that therapy response rates in gerd are related to the degree of acid suppression achieved. Having an appropriate discussion with a physician is key to understanding the condition, available treatment options and the degree to which acid suppression can be achieved.

Proton Pump Inhibitors are all benzimidazole derivatives that control gastric acid secretion by inhibition of gastric H+,K+ -ATPase, the enzyme responsible for the final step in gastric acid secretion from the parietal cells.

Gastro Esophageal Reflux Disease (GERD), commonly known as Acid Reflux, is a disease that is now affecting a lot of teenagers over the world. GERD is a heartburn caused by a leaky valve at the base of your esophagus that allows stomach acid to regurgitate (Livestrong). GERD is also caused by a bacteria found in your stomach known as Helicobacter Pylori. H. Pylori attacks the lining of your stomach and later when it has done enough damage, acidic fluid is able to get through the lining and into your esophagus, causing a heartburn (WebMD). Most people do acquire h. pylori during their childhood but most only develop its symptoms later on in life and some are never affected by the bacteria, never developing any symptoms.

I believe that an empiric trial of anti-reflux therapy is indicated, thus I have prescribed her Nexium 20mg daily.

GERD is a reflux disease that is triggered by a weak lower esophageal sphincter. The lower esophageal sphincter, LES, is located between the end of the esophagus and the stomach. A closed lower esophageal sphincter prevents acid and bolus from returning to the esophagus. Those diagnosed with GERD experience a weak lower esophageal sphincter, which can cause bolus and acid to travel up the esophagus, causing a heart burning sensation. Overtime, a continuous exposure to the stomach acid and bolus can cause the esophagus to erode, which may result in bleeding as well as breathing problems.

But if the stomach does not reach the proper level of acidity the LES stays open which means stomach acid refluxes into the esophagus.

. Gastro-oesophageal reflux disease is a condition in which the reflux of gastric substance into the throat incites manifestations or entanglements and disables personal satisfaction. Run of the mill side effects of ageal reflux disease are indigestion and spewing forth yet gastro-oesophageal reflux sickness has likewise been identified with additional oesophageal indications, for example, asthma, ceaseless hack and laryngitis. The pathogenesis of gastro-oesophageal reflux illness is multifactorial, including transient lower oesophageal sphincter relaxations and other lower oesophageal sphincter weight variations from the norm. Thus, reflux of corrosive, bile, pepsin and pancreatic chemicals happens, prompting to oesophageal mucosal damage.

People who suffered from GERD or Gastroesophageal reflux disease, namely chronic diseases that cause acid reflux up from the stomach into the esophagus, often affected by Barrett's Esophagus. You can reduce this condition by avoiding the risk factors.

Acid reflux is when a little bit of the acid content in the stomach tends to flow up into the esophagus which then goes into the gullet.The gullet moves food down from the mouth. Acid refluxs are commonly thought to be the same as heart burns but acid refluxs are quite different.

Many people have a hiatal hernia with no symptoms. The larger the hernia, the more likely that you will have symptoms. In some cases, a hiatal hernia allows stomach acid to flow back into the tube that carries food from your mouth to your stomach (esophagus). This may cause heartburn symptoms. Severe heartburn symptoms may mean that you have developed a condition called gastroesophageal reflux disease (GERD).