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Essay On Classification Of Avian Avulavirus Serotype-1

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Classification of Avian Avulavirus serotype-1 The causative agent of ND, is now classified as a species Avian avulavirus serotype-1 (AAV-1). Recently, the 10th annual International Committee on Taxonomy of Viruses (ICTV, EC 48, Budapest, Hungary, August 2016), categorized the virus as a member of the genus Avulavirus of the paramyxoviridae family (Alexander, 1997) in the order of mononegavirales (Knipe and Hetsley, 2001; Mayo, 2002; Murphy et al., 1995; Afonso et al., 2016). The order mononegavirales has undergone several changes in 2017 ICTV report. It’s comprised of eight families hosting viruses with non-segmented, linear, single-stranded and negative-sense RNA. The designated Paramyxoviridae family is now where the causative agent of…show more content…
Several antigenic and genetic diversity are recognized (Aldous et al., 2003; Alexander, 1997; Kim et al., 2007) using molecular-based techniques for analyzing the genome sizes (Knipe and Hetsley, 2001). The classification schemes adopted for Avian Avulavirus-1, is based on the sequences and phylogenetic analysis of HN, L, M and F genes and these have been advanced to group isolates (Aldous et al., 2003; Liu et al., 2011; Miller et al., 2010; Pedersen, 2010). Depending on the researcher’s preference, nominal differences arise in the grouping of isolates. Using genotypes or genetic lineages proposed by Aldous et al., Avian Avulavirus-1 is placed in serotype-1 with six lineages and 13 sublineages (AVV-1) (Aldous et al., 2003), to which three other sublineages were added (Snoeck, et al 2009). Most ND vaccines are grouped under Class II, genotype I and II while genotype III - X are velogenic that might be used as challenge viruses in vaccination experiments. Using the genome size scheme, Avian Avulavirus-1 is placed into six lineages (1 to 6) (Alexander and Senne, 2008). Detailed analysis reveals sub-lineages in lineage 3 and 4 (a to d) and in lineage 5 (a to e). On the other hand, using genomic characterization and restriction site mapping of HN, F and L
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