Essay On Concomitant Asthma

Cystic fibrosis is an existence restricting autosomal recessive disorder that influences 70,000 people around the world. The condition is known to affect principally those of European descent, though cystic fibrosis has been accounted for in all races and ethnicities. [12] Unusually viscous emissions in the airway of the lungs and in ducts of the pancreas in people with cystic fibrosis cause hindrances that prompt aggravation, tissue harm and destruction of both organ systems. Studies show that Cystic Fibrosis is more prominent in White Americans than African Americans, and Hispanics. A large number of Americans are carriers of this mutated Cystic Fibrosis gene, however if an individual is affected they must acquire two of these genes keeping

Brand PL, van der Ent CK. The Practical Application and Interpretation of Simple Lung Function Tests in Cystic Fibrosis. J R Soc Med. 1999;92 (Suppl 37):2–12. [PMC free article] [PubMed]

With CF people lack the special enzyme to break up mucous. Without the mucous breaking up the person cannot breathe because the lungs are filled. In life the body cannot function with enough oxygen.

A widely accepted Caucasian disease has since changed; as cases of its existence are appearing in the South Asian Population (Orenstein, Rosenstein and Stern, 2000). First discovered in 1989, Cystic Fibrosis (CF) is a genetically predetermined condition, its presences is lifelong and highly complex, which is why many CF sufferers and families develop various mechanisms in order to adapt to the condition (Tippingemail, Scholes, Cox, 2010). Cystic Fibrosis causes the body to develop thick, sticky mucus which clogs the lungs and affects other organs in the body, mainly the pancreas. The layer of mucus if untreated develops in to a chronic infection which can be detrimental. The pancreas of a CF patient is most vulnerable, once the mucus has

Asthma is a chronic inflammatory disease of the airway that impacts a person’s and their family’s quality of life. In people with asthma, their airway becomes constricted with swelling and excessive mucous. This constriction or narrowing of the airway makes it difficult for the person with asthma to breath (Massachusetts Department of Public Health, 2009). If asthma is left uncontrolled, it leads to further wheezing, coughing, shortness of breath, tiredness, and stress. (Massachusetts Department of Public Health, 2009).

Cystic Fibrosis is one of the most common and fatal genetic diseases in the United States. Cystic Fibrosis is a disease that causes the body to produce a thick, sticky mucus that clogs the lungs. This can lead to infection and blocks in the pancreas, which stops digestive enzymes from reaching the intestine where they are required in order to digest(“Learning About Cystic Fibrosis,” 2013). Cystic Fibrosis can go undiagnosed for a long period of time. For example, Mackenzie Dondanville 11 years old, four years ago, who had been coughing a lot for the previous year and a half. Due to her being physically athletic while competing in soccer, her pediatrician thought her cough and shortness of breath was due to exercise-induced asthma. It wasn't until Mackenzie's prescribed inhaler isn't working, that they realized something more was going on (“Mackenzies Story,”2018).

Nonetheless, the disease is most common among Caucasians of Northern European descent. Latinos and American Indians are commonly affected too (NHBLI, 2013). According to Beery and Workman (2012), the prevalence rate of CF in the United States among Caucasians is 1 in 3000 live births, whereas a carrier status is estimated to be at 1 in 20 to 30 Caucasian Americans (p. 192). To contrast, the probability of CF in Hispanic American populations is 1 in 13, 500 and 1 in 15,100 for African American. An estimated 70, 000 individuals suffer from cystic fibrosis worldwide with 30,000 of that total residing in the United States. In addition, approximately 1,000 new cases are diagnosed each year (Schechter,

CF is found in nearly one of every three-thousand live births. But more than eighty percent of the patients are diagnosed by age three. Today, nearly forty percent of the diagnosed inhabitants are at the age of eight-teen or older.

CF multi-disciplinary team also undertakes clinical research of the condition, where new treatment and therapies are

Breathing is a vital process for every human. Normal breathing is practically effortless for most people, but those with asthma face a great challenge. During an asthma attack, breathing is hampered, making it difficult or even impossible for air to flow through the lungs. Asthma is an increasingly common problem, and has become the most common chronic childhood disease. At least 17 million Americans suffer from it(1), and although it can be fatal, it is usually not that severe(4). There is no cure for asthma, but with proper care, it can usually be controlled.

Doctors can then confirm the diagnosis by using what is called a “sweat test.” A sweat test measures the amount of salt that is in the sweat. Doctors will trigger the sweat on a small patch of skin on the arm or leg (MFMER, 2016). Other tests consist of a chest x-ray, lung function tests, or a spit test. There is many treatments that a doctor can do to help lessen the symptoms of CF, but at this point there is no treatment that can cure you from CF. The sooner you catch these symptoms and try to counteract them with treatments the better off you are. Newborn screening helps with early diagnosis. There’s medications such as antibiotics that treat and prevent lung infections. Doctors also use anti inflammatory medications to lessen swellness for airways to the lungs. Patients diagnosed with CF can inhale medications such as mucus thinning drugs to keep their muscles loose. (Diagnosed, 2016). Lastly, there is chest physical therapy, vest therapy, surgery, and other procedures. Doctors are continuing to try to find a cure to CF, but as of right now there is none. New data, research, and technology is helping reduce the amount of people devastated by this

Cystic fibrosis, also known as CF, affects over 30,000 children and adults world-wide. CF is a disease in the lungs and digestive system and is still incurable today. It is a disease that causes thick, abnormal mucus in the lungs, nasal polyps, fatigue, and can also damage organs in a person’s body. According to www.cff.org/aboutcf, over 70% of CF patients are diagnosed at two years of age. Cystic fibrosis is one of the most life-threatening diseases in the United States and is very common amongst chronic diseases. Cystic fibrosis is most commonly diagnosed in young children and sometimes adults.

Throughout the years knowledge about asthma has grown, as well as treating it effectively. Over 300 million people are said to be victims of this disease with another 100 million being estimated by 2025 globally (Currie and Baker, 2012). In the United Kingdom, asthma is increasingly becoming one of the leading disease affecting individual of different age, ethnicity, race and gender. British Lung Foundation (2011) stated that it is more common at childhood stage and can also occur at a later age. According to Asthma UK (2014) asthma in men is less prevalence than it is in women and children troubled more with asthma than adults. Recent data in the UK shows that in children and occupational asthma in adult is on the rise with an estimate

Asthma is the most common worldwide chronic condition that affects both young and old. It is a condition in which the air way passages are narrowed leading to symptoms of wheezing, shortness of breath, chest tightness, and cough (Bijanzadeh, Mahesh, Nallur 1). Asthma is caused by increased infiltration of inflammatory cells into the airway, constriction, airway smooth-muscle hypertrophy, and mucous hypersecretion in the bronchiolar walls of the lung (Bijanzadeh, Mahesh, Nallur 1). Most asthma attacks are short, a few minutes to a few hours, and the person recovers completely this is called episodic asthma disease. However, those who have acute severe asthma is much more serious because the asthma attacks lasts for days or weeks, and

CF patients present a diverse amount of manifestations and degrees of severity, which could initially be attributed to allele heterogeneity (Keren et al, 1990). The CFTR mutations were strongly correlated with exocrine function disturbances and well imputed to hypertonic sweat. Although, CFTR disorder alone could not determinate lung phenotype. The literature describes a strong influence of genetic and non-genetic variations in airway manifestations of CF. Cutting et al’s meta-analysis (Cutting et al. 2016) found that genetic modifiers were responsible for 50% of variations in lung conditions. The remaining portion was mainly attributed to environmental and stochastic influence (see Figure 1). At least 50 encoding genes have been investigated for influencing CF phenotype (Cutting 2015). A list of these genes is beyond the purpose of the present work.