Essay On Hemophilia Royal Disease

Hemochromatosis is a genetic disease in which there is too much iron that builds up in your body, this is referred to as an iron overload. Iron is an essential nutrient found in many foods but can be toxic to our bodies if we have to much. “Normally, humans absorb about 8-10% of the iron found in foods that they eat.” People with Hemochromatosis can absorb up to four times more iron than a normal human being. Since our bodies have no natural way to get rid of the extra iron, it gets stored in your body tissue including the liver, heart, pancreas and many other areas of our body can also be infected by this iron overload.

Hemophilia is an X-linked recessive disease in which blood lacks blood-clotting proteins. Females have two X chromosomes, indicating that they are generally carriers and transmit the gene to their sons. People with mild hemophilia bleed after surgery, injury, or trauma. Severe hemophilia produces spontaneous internal bleeding in joints and muscles. Fortunately, medicines and lifestyle changes offers hemophiliacs fairly normal lives. Through learning about hemophilia, I became interested in genetic diseases and finding a cure for those

The mother feels guilty because her son was born with this disorder which in most cases is inherited. According to the Mayo Clinic in most cases hemophilia is inherited, however nearly 30% of children/adults have no family history of the disorder. The 30% suffer from a genetic mutation. (Staff, B.M. ((n.d.)). Hemophilia. Retrieved September 27, 2016, from

The genetic disorder of Hemophilia is where the clotting factors of the blood are absent or deficient, causing it to be a dangerous disorder to the people who have it. This disorder is where the people who have it will bleed easily and accessibly. Different types of hemophilia are classified by different deficient clotting factors in the blood. Treatments for hemophilia are available, including transfusions of frozen

Meyers, R., W. Adams, K. Dardick, J. Reinisch, F. Reyn, T. Renna, and O. McIntyre. "The Social and Economic Impact of Hemophilia--a Survey of 70 Cases in Vermont and New Hampshire." The Social and Economic Impact of Hemophilia--a Survey of 70 Cases in Vermont and New Hampshire. American Journals of Public Health, 1 Apr. 1972. Web. 30 Aug. 2015. .

Don Francis wanted to prove this fact by proving that 89% of hemophiliacs were now affected with the virus. The red cross still disagreed because there was no absolute proof that the virus was being transmitted through transfusion. This caused the professionals to have to research more. They researched the virus more and decided to test it with a antivirus and they found a new virus what they called a new retrovirus: AIDS. It took a while for the red cross and other professionals to actually believe that the virus were affecting many across the

The first disease that will be discussed is hemochromatosis. Hemochromatosis mainly targets the liver, heart, pancreas, joints, testicles, thyroid, and skin organs. The symptoms of hemochromatosis include: “liver failure, heart failure, diabetes, arthritis, infertility, psychiatric disorders, and cancer.” Hemochromatosis was first described by Armand Trousseau in 1865. Then, in 1889 Friedrich Daniel von Recklinghausen coined the term hemochromatosis. Afterwards, a group of California scientists isolated the gene that caused hemochromatosis in 1996. Hemochromatosis affects around one in every two hundred people that have Western European ancestry. Liver biopsies were commonly used to diagnose hemochromatosis. Hemochromatosis was often treated with phlebotomy (bloodletting) to reduce the amount of iron in the bloodstream. As “the most common genetic variant in people of Western European descent”, hemochromatosis has impacted humanity in a profound way. Many more people might have died in the Bubonic Plague and in subsequent plagues if not for the evolutionary advantages provided by hemochromatosis. In the present day however, hemochromatosis is a dangerous disease if fully manifested in a person and left untreated. Hemochromatosis made Europeans more resistant to bacterial infections like the Bubonic Plague. This happens because hemochromatosis reduces the iron levels in macrophages. Macrophages are white blood cells help fight and contain diseases. Also, macrophages usually

According to the CDC website, Hemophilia, is a hereditary bleeding disorder which affects mostly males due to X chromosome singularity. Hemophilia is a medical condition in which the blood clotting becomes a challenge for those affected. Symptoms include spontaneous bleeding from injuries or surgery. Blood contains many proteins called clotting factors that assist in blood coagulation, however; those individuals with hemophilia have low levels of either factor VIII or factor IX. The severity of the condition is determined by the amount of factor in the blood thus the lower the amount of the factor, the higher the chances that spontaneous bleeding will occur leading to more severe health complications.

Alexandra did little to dispel growing discontent for her husband. She ruled side by side with her extremely influential friend, Grigory Rasputin. Rasputin was the only person able to treat the hemophilia of her only son, Alexis, heir to the Russian throne. Rasputin’s close relationship to the Empress allowed him to gain his own sense of power. He quickly began dismissing efficient ministers and appointing incompetent ministers solely on whether or not they supported him. Nicholas began to be seen as a man who willingly let his incompetent wife run the government, while he attempted to regain his pride on the western front. Conservatives began to plot against Nicholas in order to save their monarchy.

When he was three days old his doctor diagnosed him with severe type A Hemophilia after a circumcision

The first generations are skipped, although Nicolas (1904-18) was a hemophiliac, neither his parents nor grandparents were. This pattern occurs in several other places of the pedigree, and indicates a recessive mode of inheritance. From the biochemical nature of the defect, scientists have determined that hemophilia is a recessive trait. All the affected individuals are sons, strongly suggesting that the defect is a sex linkage trait. Since males are hemizygous for the X chromosome, more males than females should have the phenotype of

Attention Getter: About 400,000 people are living with hemophilia, a rare blood disorder that causes blood to clot abnormally. Many of these people also develop HIV and AIDS, an immune deficiency. Even more shocking is the 78 million people living with HIV. All of these conditions are lifelong and fatal. Over 40 million people each year die of HIV or hemophilia. What 's even more terrifying is the amount of misinformation pertaining to these subjects, such as the difference between HIV and AIDs, and the causes of these conditions.

The 12th of August 1904 was a great event for the Romanov family, who were the last ruling dynasty of the Russian Empire – it was the birth of their long-awaited son Tsarevich Alexis, the successor to the Russian throne. Unfortunately, the sole heir was seriously ill with an incurable disease called hemophilia. Hemophilia is an inherited disease characterized by the inability to form blood clots properly. In other words, any minor cuts might be almost fatal for people, who suffer from this disease. The condition is passed on to males through females, who do not manifest the symptoms of the disease themselves. The Tsarevich Alexis inherited hemophilia from his mother, the tsarina Alexandra Feodorovna, who was the granddaughter of Queen Victoria.

Hemophilia is a problem with the blood in a person that causes them to bleed not any faster than normal, but they often bleed for a longer period. Their blood is missing the clotting factor (a protein in the bloodstream that works to control bleeding). Hemophilia is quite rare; roughly 1 in every 10,000 persons are born with it. Rarely, hemophilia can be an acquired disease which just means a person is not born with it, but will develop it during their lifetime. This rarity occurs when a person's immune system forms antibodies that attack the clotting factor in the blood. The entire antibody population fights against the blood to prevent the clotting factors from working properly.

Alexis Romanov, son of the Tsar Nicholas Romanov II had severe bleeding episodes which we now understand as Haemophilia- a single gene causing blood disorder. This gene was said to have originated from Queen Victoria, carried, and spread by her daughters to the Royal families of Prussia , Spain and Russia – which is how Alexis, the sole heir to the Russian throne , got it.