leucine. This display the possibility of L. fermentum to enhance the bioavailability of milk protein and consequently the infant growth and development (Basavanna & Prapulla, 2013).
The gut microbiota and fat metabolism
Lactobacilli have the proficiency to hydrolyze bile salts via the secretion of bile salt hydrolase enzymes (Kumar et al., 2011). This hinders bile salt reabsorption and in sequence increase bile salt loss in fecal. This result in a decrease of serum cholesterol because of the involvement of cholesterol in bile acid synthesis (Favier et al., 1995). Also, dietary supplementation with propionic acid demonstrated hypocholesterolemic influences in rats and pigs (Thacker et al., 1981; Chen et al., 1984). Propionate may inhibit
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PYY favorably binds to the neuropeptide Y receptor type 2 (Y2), highly expressed in the hypothalamus, which is recognized to be an essential for appetite control (Broberger et al., 2008). In rats, consumption of lactitol, a fermentable carbohydrate, dramatically augmented postprandial PYY plasma level, and reduced weight gain compared with control. However, in human, acute supplementation of lactitol was linked with a significant reduction of postprandial PYY drop at 5 hours and a trend to decreased appetite (Gee & Johnson, 2005). Moreover, following fermentable carbohydrates supplementation, increased plasma PYY and GLP-1 levels have been detected in rats (Zhou et al., 2008), and human individuals (Greenway et al., 2007). GLP-1 is released after food consumption (Elliott et al., 1993), has been revealed to delay gastric emptying (Nauck et al., 1997), and gut motility (Schirra et al., 2002) in humans, inhibit food intake (Turton et al., 1996). SCFA might control entire transit time of digesta throughout the intestine (Dass et al., 2007). Entire gut transit time was statistically associated with fecal SCFA concentrations especially butyrate (Lewis & Heaton, 1997). Also, butyrate administration via dietary supplementation stimulated energy expenditure and promoted mitochondrial function in mice (Gao et al., 2009). SCFA have been described to cause satiety and reduce food intake. In human, it was shown that the dietary
Breast milk provides all the necessary proteins, vitamins, sugar and fats essential for an infant’s growth
When analyzing the comparison of the percentages intake of carbohydrates, the dietary recommended intake (DRI) in iprofile was 45-65%. The outcome of the three-day process displays that I am within an acceptable range of 57%. However, the foods that were part of the three-day diet consisted of various carbohydrates such as complex, simple, and fiber. Despite, that many people try to avoid or cut starches, they are vital to an individual health for several reasons. However, the body used carbohydrate as the primary source for providing energy, to protect against diseases, controlling weight, which all factors are important in a healthy diet (Mayo Clinic, 2016). An importance of carbohydrates in the diet, it can easily store in both the muscles and liver for future use and plays a role in the organs such as the kidneys, brain, and the heart for operating properly (Medline Plus, 2016).
The aim of this investigation is to explore the effect of different concentrations of bile salts on the time taken for the lipase enzyme to break down fat.
Throughout our lives we have been told that milk is good for our body and helps to toughen our bones. Drinking milk started when people domesticated animals for food, which happened around 7500 years ago in the central Balkans and central Europe. By that time consuming milk was not as common as it is today. It was only farmers in some specific regions that were using cow’s milk. Milk’s market grew the mass production of meat in the 15th century. Afterwards in the 17th century, the idea of eating out and going to restaurants was born and fast food industries, started using animal’s meat for producing their meals. The rate of milk users grew with the rate of meat users and milk’s market got bigger and bigger every day. Mothers
In “The Mysteries of Milk,” Natalie Shenker, PhD and co-founder of the Hearts Milk Bank, emphasizes the importance of breast milk, writing “it is critically important to prevent infections and necrotising enterocolitis (NEC), a catastrophic gut condition that carries a mortality rate of 40%” (Shenker, 2017, p.11). Breast milk, especially colostrum, which is produced two to three days after birth, provides not only an energy-rich source of food for an infant but is composed predominantly of white blood cells which can “engulf and absorb harmful microorganisms” (Shenker, 2017, p.12). The cells are breast-specific macrophages that produce lactoferrin, an iron-binding protein that helps the infant absorb and store protein, and lysozyme, an
In 1960 it was found that germ-free animals deposit cholesterol in larger amounts and at a quicker frequency then those who are not considered germ-free. A study conducted in 2012, evaluated the use of Lactobacillus reuteri NCIMB 30242 capsules, which resemble the strain of bacteria found within probiotic- enriched yogurt. The study revealed that patients who were administered this microbial capsule exhibited a decrease in non-cholesterol sterol absorption and serum cholesterol which over time decreased their LDL-cholesterol (Jones, Martoni & Prakash,
Coll, A. P., Farooqi, I. S., and O’Rahilly, S. The hormonal control of food intake. Cell. 129(2), 251-262 (2007).
This primary article aimed to determine whether Wistar rats had a change in weight and food intake after consuming non- nutritive sweeteners and sucrose. 30 Wistar rats weighing about 200-300 g were taken for this experiment. They were kept in a 44 x 34 x 16 cm cage to control their activity, and divided into 3 groups of 10 Wistar rats, where each group was given either aspartame, sucrose or saccharin incorporated with yoghurt and water. This experiment was of 12 weeks, after which their body mass was measured. The final mass was determined by substracting the basal mass from the gained mass. It could be seen that the Wistar rats consuming aspartame and saccharin gained more weight compared to the Wistar rats feeding sucrose. It could be concluded
The main purpose of this lab is to identify and separate the main components of milk. To do this an understanding of the properties of these components in needed to separate them from one another. We will be separating the components with their polarity or non-polarity and the temperature at which specific components precipitate. To do this we will be using hot plates, gravity filters and vacuum filters1, water and ice baths, and blot drying.
Abstract Lactose is recognised as a disaccharide; in other words, it consists of glucose and galactose and two smaller sugars bound altogether with a covalent bond. In the form described, lactose is indigestible by us humans; therefore it must be hydrolysed, or broken down, for our body in order to process it. Lactase catalyses this process by decreasing the energy required for hydrolysis to happen. Lactase is a digestive enzyme that catalyses the breakdown of lactose, a sugar found in milk.
Bile has bile salts, or in other words, bile acids in it. Previous studies of fish, whose bile should remain the same no matter what they eat, have shown that there were changes in the bile salt synthetic pathway. The original bile salt synthetic pathway was thin and very simple. Over many generations, it has become longer
A lot of these problems seen in formula feed babies are due to the fact that the particular composition of the formula doesn’t suit their digestive system. Breast milk consists of the optimum proportions of fats, carbohydrates, proteins, vitamins, minerals and water. It is extremely digestible for a new-born baby because the milk is naturally refined to perfectly suit the baby’s digestive system. The milk also contains growth factors such as, epidermal growth factor (EGR) and insulin-like growth factor. The epidermal growth factor works by helping to prepare the lining of the gut to absorb the nutrients from the milk consumed. Insulin-like growth factor is believed to be one of the primary factors regulating early growth and development. Breast milk also contains essential fatty acids that are not present in most formula milk products. The two essential fatty acids present in breast milk are docosahexaenoic acid and arachidonis acid. Both of these play a vital role in optimal development of the central nervous system, intellectual and visual development in babies. Furthermore, one of the most prominent advantages associated with breast feeding over formula feeding babies is that, breast milk naturally changes composition to correspond to the stage of development of the infant. For example, colostrum is the name given to the first milk produced post-delivery. It has an abundance of white cells and antibodies, it also contains a
The gallbladder stores and concentrates bile. If the gallbladder was damaged or dysfunctional there would be softer and more frequent stools. (Audesirk, T., & Audesirk, G. (1999). Retrieved November 21, 2015 from Chapter 29: Nutrition and Digestion. In Biology: Life on Earth (5th ed., p. 585, 586). Upper Saddle River, N.J.: Prentice Hall.) (General Surgery- Gallstones (Cholelithiasis). (n.d.). Retrieved November 21, 2015, from
Abstract – Yogurt is a product of lactic acid and lactose. In order to produce yogurt, milk is pasteurized (at 45 degrees Celsius) and the inoculum is added followed by incubation. Over a period of 7 days, yoghurt fermentation was attempted using lactobacillus cultures. A liter of milk was supplied and plain yoghurt was used as a starter culture as it contains the necessary bacteria to ferment lactose and produce lactic acid. The milk was added to a flask: then boiled, cooled and inoculated. The milk was incubated for a week and all the while the milk was tested for changes in pH, density, mass and physical changes. The values obtained were then used to determine the growth kinetics of Lactobacillus bulgaricus.
This substance is produced when a human digests lipids or fats. According to Sareen Gropper and Jack Smith’s “Advanced Nutrition and Human Metabolism” bile is produced through the process of chemically altering cholesterol, which is a type of fat found in a human’s blood. This process takes place in the liver and bile acids are produced. These bile acids are then conjugated or united with taurine and glycine to produce biosurfactants known as bile salts. The existence of bile salts inside of bile gives the substance the capacity to amalgamate lipids and fats with their aqueous (watery) environment inside of the gallbladder. According to Sareen Gropper and Jack Smith’s “Advanced Nutrition and Human Metabolism” bile is released from its origin (gallbladder) into the small intestine. Through the process of emulsification the bile substance in the small intestine disintegrates fats into much tinier particles which can be digested and absorbed at a much more efficient and quicker rate. This evidently shows that without bile and in turn bile salts the digestion of fats will not be