preview

Essay On L Fermentum

Decent Essays

leucine. This display the possibility of L. fermentum to enhance the bioavailability of milk protein and consequently the infant growth and development (Basavanna & Prapulla, 2013).
The gut microbiota and fat metabolism
Lactobacilli have the proficiency to hydrolyze bile salts via the secretion of bile salt hydrolase enzymes (Kumar et al., 2011). This hinders bile salt reabsorption and in sequence increase bile salt loss in fecal. This result in a decrease of serum cholesterol because of the involvement of cholesterol in bile acid synthesis (Favier et al., 1995). Also, dietary supplementation with propionic acid demonstrated hypocholesterolemic influences in rats and pigs (Thacker et al., 1981; Chen et al., 1984). Propionate may inhibit …show more content…

PYY favorably binds to the neuropeptide Y receptor type 2 (Y2), highly expressed in the hypothalamus, which is recognized to be an essential for appetite control (Broberger et al., 2008). In rats, consumption of lactitol, a fermentable carbohydrate, dramatically augmented postprandial PYY plasma level, and reduced weight gain compared with control. However, in human, acute supplementation of lactitol was linked with a significant reduction of postprandial PYY drop at 5 hours and a trend to decreased appetite (Gee & Johnson, 2005). Moreover, following fermentable carbohydrates supplementation, increased plasma PYY and GLP-1 levels have been detected in rats (Zhou et al., 2008), and human individuals (Greenway et al., 2007). GLP-1 is released after food consumption (Elliott et al., 1993), has been revealed to delay gastric emptying (Nauck et al., 1997), and gut motility (Schirra et al., 2002) in humans, inhibit food intake (Turton et al., 1996). SCFA might control entire transit time of digesta throughout the intestine (Dass et al., 2007). Entire gut transit time was statistically associated with fecal SCFA concentrations especially butyrate (Lewis & Heaton, 1997). Also, butyrate administration via dietary supplementation stimulated energy expenditure and promoted mitochondrial function in mice (Gao et al., 2009). SCFA have been described to cause satiety and reduce food intake. In human, it was shown that the dietary

Get Access