Essay On Sickle Cell Disease

Sickle Cell Anemia is a group of disorders that cause red blood cells to become misshapen and break down. Sickle Cell Anemia affects many people all over the world; Sickle cell disease is the most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans (Ashley-Koch, Yang and Olney). Sickle Cell Anemia causes your red blood cells to be thin, stiff, and shaped like a sickle. But your red blood cells are supposed to be round and soft. When a person is diagnosed with sickle cell anemia the blood cells start to become clogged blood vessels, which can cause a great amount of health issues including: infections, stroke, and acute chest syndrome. People get sickle cell anemia by inheriting a mutated gene from both of their parents. On the down side, there is not currently an effective cure for sickle cell anemia, there are several different therapeutic approaches to treating and attempting to cure the disease and help people who are affected with sickle cell anemia better manage their symptoms. There have also been several great scientists that dedicated a lot of research to help find a cure for sickle cell anemia.

Sickle Cell Disease is an illness that affects people all across the globe. This paper will give a description of the sickness through the discussion of the causes, symptoms, and possible cures. Sickle Cell Disease (SCD) is a "group of inherited red blood cell disorders."(1) These disorders can have various afflictions, such as pain, damage and a low blood count--Sickle Cell Anemia.

Sickle cell anemia occurs when a person inherits two abnormal genes (one from each parent) that cause their red blood cells to change shape. Instead of being flexible and round, these cells are more rigid and curved in the shape of the farm tool known as a sickle - that's where the disease gets its name. The shape

Sickle cell disease is a disease that is most prevalent in people of African descent along with people of Mediterranean and Middle Eastern origin. This disease is known to affect about 70, 000 Americans and about 2 million people carry the trait (meaning that, they carry a single gene mutation).

Each year in the US, an average of 75,000 hospitalizations are due to sickle cell disease, costing approximately $475 million. Sickle cell disease is also associated with significant mortality. Among children, the primary causes of mortality are bacterial infections and stroke. In adults, it is more difficult to attribute specific causes to mortality, but it appears that individuals with more indicative disease are at risk for early mortality.

This mutation paper is to give information on the Sickle Cell disease. This is a negative disease to have because the Sickle Cell Disease decreases the health of the person that has the disease and limits what they can and cannot do. Sickle Cell Disease is a red blood cell disease that causes ab normal hemoglobin to from in the veins. Hemoglobin is the protein that carries oxygen throughout the body to help with the respiratory system. The cause of the genetic mutation is inheritance or getting the disease from the parents the disease is found on chromosome 13 while the hemoglobin is still in beta phase on gene HB A. The disease typically shows symptoms within the first 5 to 6 months of birth and being diagnosed with Sickle Cell Disease. The symptoms include painful swelling on the hands and feet, and Jaundice, which causes a white color to form under the eyes, and turns the skin color yellow.

Sickle Cell Anemia has proven to be one of the most widespread genetic diseases in America, affecting 100,000 or more individuals according to the NHBLI (2008). Each person affected by sickle cell anemia must seek out expert advice and care for combating the disease, but as of late, care has been lacking in the medical field for these patients. Therefore providing optimal care and effective treatments for patients with sickle cell anemia will involve more research and funding in the future. Studies have shown that treatment for sickle cell patients is lacking and drugs are scarce and sparse, which has left this population medically neglected. The need to focus more research and allocate more funding toward sickle cell research is evident

Sickle cell anemia is an inherited disease in which the body is unable to produce normal hemoglobin, an iron-containing protein. Sickle cell anemia is a disease in which the body is unable to produce normal hemoglobin, an iron-containing protein. Abnormal hemoglobin can change cells that can become stuck in narrow blood vessels, blocking oxygen from reaching organs and tissues. Tissue that does not get a normal blood flow eventually becomes damaged. This is what causes the problems of sickle cell disease. As to this day there is really no cure for Sickle Cell Disease. I choose to topic because there are a number of persons in my family who have Sickle Cell Disease (SCD). From personal experience I knew that the disease could take a toll on

Sickle-Cell Anemia is an inherited, chronic blood disease in which the body produces abnormally shaped red blood cells. When the blood cells become crescent/sickle shaped, they are unable to deliver adequate amounts of oxygen to other cells. Also, these unusual “sickle” cells block blood pathways to the limbs and organs, limiting the amount of blood flowing throughout the body. It causes pain, organ damage, and anemia (low blood count). Unfortunately, however, when sufferers are born with this disease, they live life knowing it is incurable.

So what exactly is Sickle Cell Anemia? Sickle cell is an inherited blood disorder that affects red blood cells due to the presence of an abnormal form of hemoglobin, namely hemoglobin S. Sickle cell has a lot to do with natural selection and is known as genetic disorder. You may never know who will have it in your family. It will not affect everybody. Sickle cell effect the red blood cells in your body. The red blood cells in your body begin to become deformed. They begin to look, “crescent shaped and have difficulty passing through small blood vessels, which could slow or block blood flow and oxygen to parts of the body.” The cresset shaped is where sickle cell gets its name from. When sickle cell mutates in your body, it begins to effect the muscles and even could possible effect the oxygen flow into your body. When the oxygen is blocked, this causes pain and even harm to your organs and even muscles. When this happen, this effects a person ability to be active. According to web MD, “Severe pain is an emergency called acute sickle cell crisis. A person may not know what brought on the pain, but infection and dehydration are common triggers.”

Sickle Cell disease is a genetic disorder found primarily in minority descents throughout the world. Because of recent accomplishments in medical research, those diagnosed with Sickle Cell disease are able to lead much more fulfilling lives instead of lives filled with excruciating pain. Though crises caused by the disease process may be unavoidable, comfort can be achieved through proper nursing care. This paper will explain the obstacles caused by sickle cell disease in a patient currently consumed by crisis.

Sickle cell disease is a chronic condition that a person can inherit from their parents in which it effects the globular structure of the patients red blood cells. A more sickle shaped structure, which can alter a person’s blood flow, replaces the more common globular structure. This impairment in blood flow can lead to blood clots, severe debilitating pain and damage to vital organs such as the liver, kidney and spleen. This disease currently affects over 90,000 people in the United States, with the majority of them being African American and

Sickle Cell anemia is associated with lifelong morbidity and reduced life expectancy.All infants are screened, with findings confirmed by hemoglobin electrophoresis, a complete blood count, reticulocyte count, and peripheral blood smear.Treatment goals include fluid replacement therapy, pain management, and symptom control. Sickle Cell anemia is prevalent among African American but also common in the Hispanic

Irregular shaped sickle cells do not transport enough oxygen to perfuse body tissue, tissue not receiving enough oxygen causes more cells to sickle. An abnormal shaped sickled cell may become lodged to a blood vessel where other cells then bind to it and begin to form a clump. The blood vessels continually attach to each other and result in a blockage of small blood vessels eventually resulting in organ damage. Sickle cell disease commonly affects the spleen before other organs. Children can suffer life threatening complications when blood is trapped in the spleen, many must have the spleen removed in early childhood causing them to have a decreased immune system therefore putting them at higher risk for infections. The leading cause of death in young children with sickle cell disease is bacterial infections. Other complications can include stroke, acute chest syndrome with pulmonary infiltrate and infection, priapism, retinopathy, kidney damage, and gallstone formation (Ball, J., & Bindler, R., 2015). Sickling of the cell can be triggered by the following: emotional or physical stress, fever, or hypoxia. Precipitataing factors can include increased blood thickness, hypoxia or low oxygen tension. Sickle cell crisis may result from extreme fatigue, infection, trauma, surgery, cold exposure or dehydration, or any other condition that increases the body’s need for oxygen or that alters the transport of oxygen. Sickled cells have a

Having Sickle Cell trait is doesn’t cause problems for the carrier but it causes problems for your kids who inherit that recessive gene, people with the trait have two kinds of hemoglobin in their red blood cells.