Ethical Case Study On Andrew Wakefield

Although there is no scientific proof that vaccines cause autism, proponents still believe that they do. The theory that vaccines cause autism were based on unproven facts and falsified information (DeStefano 81). In an article called CNS Drugs, the author writes about how a man named AJ Wakefield stun the public with a theory that the MMR vaccine may cause autism and how enterocolitis (bowel dysfunction) and MMR vaccine may be linked to autism (DeStefano 831). Even though Wakefield falsified information and his theories were proven to be discredited many people still

The controversy over the MMR vaccine started in the late 1990’s when Andrew Wakefield suggested that there was a connection between the MMR vaccine and autism in a scientific paper which he had published with several other co-authors. Although there has not been a proven fact that the MMR vaccine is the causation to autism it has brought concerns to parents and has caused a major drop in immunization rates. For example, Dannetun et al., 2005 states that, “Fear of side effects and beliefs

In order to investigate more about Wakefield’s study, Brian Deer, a journalist of British Medical Journal, carefully talked to the parents of all children who were participated in the study. Interestingly enough, he revealed the fraud behind Wakefield’s research. The Lancet, the journal that reported Wakefield’s study, retracted the paper soon afterwards (Deer). However, the real trouble still exists. Though it has been proved by many researchers that the MRR doesn’t cause autism, many people perceive the vaccine as a threat. Dr.Nemeroff once said “it is quite difficult to get the cognitive sewage out of the water even after the real sewage is gone” (Greene).

Andrew Wakefield is a former gastroenterologist and medical researcher who was discharged from his medical register in the UK, because of his dishonest research paper he released back in 1998, that analysed a possible link between measles, mumps and rubella (MMR) vaccine and the presence of autism and bowel disease (Godlee, F., et al, 2011). Wakefield's research generated a substantial scare for the MMR vaccine and MMR vaccination rates began to drop because parents were concerned about the risk of autism after vaccination (DeStefano, F., Chen, R.T., 1999). After the paper was published by the Lancet medical newspaper, other reviews were trying to repeat Wakefield's conclusions,

The search for the cause of autism and autism spectrum disorders began in the 1990's with Dr. Andrew Wakefield, a gastroenterologist from Britain. Dr. Wakefield's research linked autism to vaccines received in infancy and childhood through intestinal disease. The vaccine Dr. Wakefield primarily looked at was the measles, mumps, rubella (MMR) triple vaccine. In 2004, most of the co-authors for the study withdrew their names after learning that Wakefield "had been paid by a law firm that intended to sue vaccine manufacturers" ("Retracted autism study," 2011). Wakefield's research

In 1998, the British medical journal called The Lancet published a controversial research paper written by Andrew Wakefield. In the research paper “Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children, ” Andrew Wakefield et al. attempted to link MMR (Mumps, Measles, Rubella) vaccinations and autism. Nevertheless, the paper seemed to successfully do that. However, this was not known was at the time was Wakefield had tampered with the findings. Furthermore, this was brought to light in 2004 by British journalist Brian Deer. In 2011, thirteen years after The Lancet published the paper, and seven years after Brian Deer exposed the paper. The Lancet finally retracted the article. A common theory

This led to the support of various unproven vaccine-autism theories by parents in both the UK and America. After findings of intestinal disease in children with autism, Wakefield claimed that separating the MMR into three different vaccinations would be safer. Since then, Wakefield’s research has been discredited, he was charged with serious professional misconduct by the General Medical Council for violating several ethical practices, and he was investigated for failing to disclose conflict of interest – a pending patent on a rival measles vaccine (Gross, 2009). Although false, many still believe wholeheartedly that vaccines are harmful.

In fact, The BMJ, or the British Medical Journal, chimed in on Wakefield’s paper. “By the time the paper was finally retracted 12 years later, after forensic dissection at the General Medical Council’s (GMC) longest ever fitness to practise hearing, few people could deny that it was fatally flawed both scientifically and ethically” (Godlee, “Wakefield’s”). Furthermore, Wakefield’s license to practice medicine was stripped away by Britain’s General Medical Council because of misconduct, including the time Wakefield paid his son’s friends £5 each to take blood samples during his son’s birthday party (Burns, “British”). More recent studies also prove that the vaccine-autism link is nonexistent. One study, performed by the Journal of Pediatrics, found that, “ … of MCO members, increasing exposure to antibody-stimulating proteins and polysaccharides in vaccines during the first 2 years of life was not related to the risk of developing an ASD” (Destefano, “Increasing”). In other words, having a young child exposed to the ingredients of vaccines does not result in the child developing autism (Destefano, “Increasing”).

One such factor helping to manifest these large-scale epidemics is a study from 1998 by Andrew Wakefield, which claimed that there was a direct link between autism and the MMR (measles, mumps, and rubella) vaccine (Smith 1). As a result, many parents refused to vaccinate their children out of fear, and vaccine-preventable diseases like measles began reappearing more in both America and Britain, the place where Wakefield conducted his study (Cohen 2). Although a later investigation by the British Medical Journal discovered that Wakefield had distorted or altered the medical records of all twelve of the study’s participants and that he had been paid $674,000 USD by lawyers attempting to sue vaccine manufacturers, the atmosphere of apprehension surrounding vaccines is still strong among many individuals, and especially parents (Cohen 1-2). But despite all the controversy and the scientifically unsupported arguments of anti-vaccine sympathizers,

The current issue I have selected to discuss is vaccinations. In particular, I will be addressing the anti-vaccination movement that has gained popularity in recent years and the contributing biases that influenced its emergence. One event stands out at as a major contributing factor to the growth of the anti-vaccination movement, the 1998 study by Andrew Wakefield that was published by the English medical journal, Lancet. This study claimed to show a connection between the MMR vaccine and autism. Even though it was just one small study, the media picked it up and it became hugely publicized.

The autism scare started 17 years ago, in the year 1998, when a paper was published in the British medical journal called The Lancet. Andrew Wakefield, M.D., a British gastroenterologist, and his colleagues were the authors of this paper which started the scare of immunizations causing autism. "Wakefield had a case study of eight children who had received the MMR and then developed symptoms of autism, says Paul Offit, M.D., chief of infectious diseases at the Children 's Hospital of Philadelphia. He also believed they had abnormal intestinal tracts and proposed a syndrome -- linking intestinal inflammation from receiving the MMR with the development of autism.” (Rope)

In 1998 a study was published by Andrew Wakefield theorizing that there was a link between autism symptoms and receiving a MMR vaccination. However, his findings are to be inconclusive considering he did not take the proper procedures to conduct a controlled study. First, he did not include control subjects in his study, so the results cannot be compared properly if there were any changes in the subjects. Second, the endoscopic or neuropsychological assessments were not done blind and the data was not collected systematically or completely. Third, the symptoms found between the children with autism and gastrointestinal problems were inconsistent. In reality, many health groups are theorizing that a vaccination does not cause autism by any

Live Science Contributor, Stephanie Pappas tell us that, “Wakefield was getting money from lawyers planning on suing vaccine makers, and he owned a patent on an alternative to the MMR (measles) vaccines,” [2] this statement is clear evidence of fraudulent activity and proves that Wakefield had corrupt reasons for undergoing this study in the first place. The second flaw to Wakefield's paper was the questionable practises of his study, for starters he based his study on twelve children that he “cherry picked,” and “although the paper claimed that cognitive problems developed a few days after the MMR vaccine, a simple investigation of hospital records revealed that wasnt so; and in several cases parents reported problems before the vaccine,” [2]. In summary, the investigation was sloppy and provided no tangible evidence that links autism to the MMR vaccine. Furthermore, it should be noted that the the link between autism and vaccines is purely coincidental, the symptoms of autism typically appear at around the age that vaccines are administered, in fact director of the Vaccine Education Centre at the Children's Hospital of Philadelphia, Dr Paul Offit confirms this says, “Children get their first dose of the MMR vaccine at 12 to 15 months, the age at which autism symptoms typically

The study revealed that 12 children who were identified with neurodevelopmental delays had measles virus in their gastrointestinal tracts, and eight of whom were diagnosed with autism (Bronfin, 2008; Chatterjee, & O’Keefe, 2010). In February of 2004, Andrew Wakefield was reported that he had received a financial contribution in relation to the manipulation of research data. In March of the same year, 10 coauthors out of 12 formally requested to retract the original findings, although they still insisted on further investigation in regard to a possible relationship between gastrointestinal symptoms and autism. On February 2, 2010, the Lancet formally retracted the paper, along with all related medical associations discredited the findings (Bronfin, 2008; Chatterjee & O’Keefe, 2010). Essentially, there is no relation between MMR vaccine and neurodevelopmental

published a controversial study in British journal Lancet where he linked MMR vaccination to autism. (Should I include what his study was based on and results?) Years later, many other studies proved it wrong but mistrust of science and mistrust of government is still there (2011). For example, Phea Paul study stated that there is no evidence that autism is cause by any vaccine and therefore no reason for parents to deny a child protection in today’s vaccines offered (2009). His study shows that if comparing risks mathematically of death or disability as a result of not vaccination a child which are small, to the risks of causing an autism spectrum disorder by immunizing it increases significantly.