Evaluation Of A Case Study

Multiple sclerosis (MS) involves an autoimmune process that develops when a previous viral insult to the nervous system has occurred in a genetically susceptible individual. B lymphocytes, plasma cells, and activated T cells, along with proinflammatory cytokines, cause inflammation, oligodendrocyte injury and demyelination. Early inflammation and demyelination lead to irreversible axonal

One important thing to know about multiple sclerosis is that there are many different types. There are four, vaguely defined, types of MS: Relapsing- remitting, Primary-progressive, Secondary-progressive, and Progressive- relapsing (Dangond). Relapsing-remitting MS, most common, is when patients experience a series of attacks followed by the disappearance of symptoms. So, in this type, multiple sclerosis attacks and then goes in to remission until another attack occurs. Its alternates back and forth. Primary-progressive MS is when there is a continuous decline in a person’s physical abilities. Secondary-progressive is when relapses are rare but the patient accumulates more disability (Dangond). Lastly, we have progressive-relapsing which is the more complex type. It is very similar to primary-progressive MS but it includes small periods where the symptoms and disease become worse (Blackstone).

Multiple Sclerosis (MS) is a neurologic disease that affects the Central Nervous System (CNS) through cellular immune response and the demyelination of CNS white matter (McCance et al., 2014, pp. 630–633). The initial causes of MS are unknown however, it is believed that it could possibly be due to an immune response to an initiating infection or an autoimmune response to CNS antigens on the myelin itself (Brück, 2005) (Miljković and Spasojević, 2013). MS is a result of the degradation of the myelin sheath surrounding neurons and therefore disrupts the transmission of action potentials along these cells. MS can display itself in the form of symptoms ranging from muscle weakness to trouble with sensation and coordination (NHS, 2016). The degradation of myelin leads the body to attempt to remyelinate the neurons, a process that in turn leads to the thickening of the cell by glial cells and this causes lesions to form (Chari, 2007). It is this thickening (sclerae) from which the disease gets its name. Sufferers of MS can either have a relapsing type of MS, in which there are episodes that lead to the worsening of symptoms for a period of time, or a progressive type of MS where symptoms gradually progress and worsen (McCance et al., 2014, pp. 630–633).

There are three different versions of multiple sclerosis (“What is MS?”). The least severe being relapsing-remitting; this occurs when a person has an attack and then there are no further

     The course of the disease is also uncertain. In general, though, the disease follows several known patterns. These patterns are grouped under the heading “chronic progressive MS.” Relapsing-remitting MS is a form of MS in which patients experience series of actively symptomatic periods called attacks followed by remissions. Secondary-progressive MS begins after RRMS. This disease advances progressively, marked by acute attacks. Primary-progressive MS is marked by a gradual worsening of symptoms, but the attacks are not acute. Patients may have temporary

In the world of neurology, there are a vast amount of neurological disorders, conditions, and diseases. One severe disease is known as Multiple Sclerosis. In this research essay, I will be discussing what multiple sclerosis is, symptoms, causes, personal experience, and treatments.

Multiple sclerosis is characterized by inflammation, demyelination, and axonal damage in the brain and spinal cord with a loss of myelin that covers the axons. As the myelin sheath regenerates, scar tissue forms, which looks like plaques on magnetic resonance imaging scans. Multiple sclerosis arises when immune-mediated inflammation activates T cells and causes the T cells and immune mediators to cross the blood-brain barriers into the CNS and attack oligodendrocytes (ie, a type of neuroglial cell with dendritic projections that coil around axons of neural cells). When the oligodendrocytes are attacked, the myelin sheath is replaced by scar tissue, which forms throughout the CNS. As a result of damage to the myelin sheath, the ability to transmit and conduct nerve impulses along the spinal cord and in the brain is interrupted, leading to muscle weakness, fatigue, loss of coordination, balance impairment, and cognitive and visual disturbance (DeLuca & Nocentini, 2011). This disease is characterized by unpredictable remissions that occur over several years. During periods of remission, the myelin sheath usually regenerates and symptoms may resolve, but the myelin cannot be completely repaired. As the disease progresses, the myelin sheath is destroyed and nerve impulses become much slower or absent and symptoms worsen. When degeneration exceeds self-repair ability, permanent disability results. There are four defined clinical types of

Multiple Sclerosis, commonly known as MS is an autoimmune disease of the central nervous system. Scientists have been studying MS since the 19th century. In MS, the body’s immune system produces cells and antibodies that attack myelin in your brain which is essential for the nerves in your brain and spinal cord to conduct electricity to perform its function. The attack on myelin results in vison loss, paralysis, numbness, muscle weakness, difficulty walking, stiffness, spasms, and bladder and bowel problems. MS has varying degrees of severity and affects people between the ages of 20-50, mostly women. Although there are treatments, there is no cause and cure yet.

“Multiple sclerosis (MS) is a disease in which your immune system attacks the protective sheath (myelin) that covers your nerves” (Mayo Clinic). The immune system is a defensive system that protects your body from diseases and illnesses such as parasites and bacteria (Science Museum). Not only does your immune system defend the human body but also the immune system can work against the body, which is known as autoimmune disease. Since the immune system is working against your body to attack the myelin, this creates an opportunity for multiple sclerosis to invade the nerves in the central nervous system (CNS). The myelin within the body acts like insulation to protect and coat the nervous system (National Multiple Sclerosis Society). Once the myelin is eroded, the nerves become exposed which then causes signals to and from the brain to become distorted or irrupted causing a wide range of symptoms to occur (National Multiple Sclerosis Society). The effect of the myelin eroding is an irreversible process (Mayo Clinic). “The damaged myelin forms scar tissue (sclerosis), which

Multiple sclerosis is an unpredictable, crippling neurological disease of the central nervous system, which affects the flow of information within the brain, and between the brain and body. The name is this disease refers to multiple areas of scarring throughout the brain and spinal cord. This scarring is a result of what happens when the body attacks itself. A substance called Myelin surrounds the nerves to help protect them (Healthline.com, 2015). Multiple Sclerosis is thought to occur in a genetically susceptible individual (although there is no evidence to show that the disease is directly inherited) influenced one or more environmental factors. MS is thought to be an autoimmune disease, however others disagree as the target of the immune

Thus, the most common symptoms of multiple sclerosis are anxiety, balance, bladder dysfunction, bowel problems, cognitive changes, depression, vertigo, fatigue, pain, numbness, sexual dysfunction, and tremor. (MSAA)This can obviously cause a slew of complications that make day to day living and quality of live difficult to achieve as this disease progress. In severe cases some individuals will lose the ability to walk. (Mayo Clinic)

Multiple sclerosis (MS) is an autoimmune condition where the body attacks the myelin covering of its nerves and brain tissue. This results in inflammation and damage to these nervous system structures, resulting in disruption in nerve signals. These changes affect motor function, manifested as loss of balance and

The debilitating disease affecting 20-45 year olds around the world: Multiple Sclerosis (MS). This unpredictable disease makes it somewhat challenging for doctors to diagnose it, as it can mock other diseases. Symptoms are variable and come in different degrees of severity. No two people have the exact same symptoms. There are four main categories of MS, with different treatment options. If controlled, MS will only have a few limitations and is, for the most part, ease to adapt to.

Multiple Sclerosis is a "chronic disease of the central nervous system characterized by the inflammation and loss of myelin" (Reingold 1). To Clarify, myelin is a white fatty substance that acts as an electrical insulation for nerve fibers in the brain. Moreover, the effect of having this disease in patients causes "Extreme fatigue, weakness, partial or complete paralysis, incoordination, memory loss, impaired sensation, and visual problems" (Reingold 1). I will be stating the many different treatments that scientists have discovered to help reduce a Multiple Sclerosis relapse.

In reading the first article Coach Knight: The Will to Win, I found the article found Coach Knight to be very offensive and mean to his players. Coach Knight did not display good leadership skills. According to the article, Coach Knight’s drive and passion for excellence was not always received as well as his record of wins and losses Snook, Per low, Delacey, 2005).