EDICAL EXPERIMENTS IN THE 21st CENTURY 1 Medical Experiments in the 21st Century . Improvements to health care would not occur if it were not for clinical trials. Clinical trials examine cutting-edge techniques to prevent, detect or treat disease (National Institutes of Health [NIH], 2014). These clinical trials have been conducted for decades; however, the protocol to which these experiments are subject has certainly become more regulated than in years prior in an effort to both establish ethical standards and to protect human participants. A Sample of Current Medical Experiments There are various types of clinical trials including: natural history studies, prevention trials, …show more content…
(2015), “The study demonstrated that plasma 25-hydroyvitamin D (25OHD) levels on admission to the surgical ICU were inversely associated with the need for mechanical ventilation in critically ill surgical patients” (p. 1). While the researchers said more research is necessary this experiment could benefit those in ICU needing assistance with respiration could have the period this is required shortened by the administering of vitamin D. Another potential benefit could be financial since using a low-cost vitamin may decrease the length of time much more expensive respiration machine would be required. New Antibiotic Effective in Treating Acute Bacterial Skin Infections A research team from Tufts Medical Center conducted two treatment trials to determine if a new antibiotic called dalbavancin was effective in treating MRSA skin infections (Boucher, Wilcox, Talbo, Puttagunta, Das, et al., 2014). Patients with MRSA were treated with either the new drug for two weeks or the currently used antibiotic, Vancomycin in order to compare infection recovery rates. This is important research because skin infections are one of the reasons that individuals are admitted to the hospital and MRSA infections by their very nature are highly resistant to antibiotics. These researchers concluded that this new antibiotic is as effective as Vancomycin in treating these infections. Family Relations Who Have Participated in a Medical Study My father was asked to
The Mythbusters observed the myth that driving whilst talking on the phone is as dangerous as driving drunk. They formed their hypothesis that driving on the phone is as dangerous as driving drunk. Then, they tested their hypothesis. They created an experiment that would have participants drive a car through a course three times. Each time a participant went through the course, they experience different conditions. The first time, both participants drove through the course normally. This served as the control group for the experiment. The second time, participants were asked questions over the phone while they completed the course, and, the third time, they were drunk when they drove through the course. Throughout the experiment, there were several independent variables in place to ensure that only one variable was being tested.
There are some trials that are being worked on around the world right now. For example, in 2013 a trial of an experimental treatment for advanced malignant melanoma took place in London at the Royal Marsden Hospital. One of the patients received three intravenous infusions, and after the second one the lumps that had been in her throat and breast had vanished. While those results were extraordinary, it is by far not the only time to have happened. There have been many similar trials that had the same results as this one. These new anticancer drugs are being called cancer inhibitors and some scientists are saying it could be the “turning point in cancer treatment.” Instead of
In a way yes, clinical trials could help the medical world and patients, but are the consequences and side effects of these trials worth the risk? In the article stated above, Netto states although clinical trials are supposed to follow specific guidelines, but “these official guidelines are not binding and enforcement is lax.” This shows that some consequences are not being considered when being acted on. I think the utilitarian would question the idea of are these clinical trials worth potential harm to the people of the society.
Methicillin-resistant Staphylococcus aureus, or more commonly, MRSA, is an emerging infectious disease affecting many people worldwide. MRSA, in particular, is a very interesting disease because although many people can be carriers of it, it generally only affects those with a depressed immune system; this is why it is so prevalent in places like nursing homes and hospitals. It can be spread though surgeries, artificial joints, tubing, and skin-to-skin contact. Although there is not one specific treatment of this disease, there are ways to test what antibiotics work best and sometimes antibiotics aren’t even necessary.
When analyzing the IR spectrum of Ruthenium complex with DMSO, the prominent peak is presented at 1105.54 cm−1. This peak indicates that S=O bonded in DMSO. For DMSO, the frequency is around 1050 cm−1. From our spectra obtained for DMSO where the S=O peak is at 1017.65 cm−1. Since the bond appears at a higher frequency, this shows that the bond is strengthened by the reaction. This indicates that when the copper metal was combined with DMSO, it bonded with the Sulfur atom. Combining ruthenium with sulfur atom caused it to donate a pi electron as a back donation.
Our country is one where every day, new medical treatments and medicines are being discovered and being approved to help Americans battle all of the different diseases and conditions that affect us. In order for us to be able to get access to those medications and treatments, many people agree to become part of clinical trials, they are the first to receive the treatments, this helps to understand how the body will be affected and if the medication will be effective. People who are part of these clinical trials, go through extensive medical testing, and they must be of sound mind and
Clinical trials, or a test before a treatment is approved to be safe for human consumption, have been dated back to the biblical times. Recorded in the “Book of Daniel” a king and military leader performed the first known clinical trial (Evolution of Clinical Research). Although his experiment was nowhere near what we conduct in today's society scientist, doctors, and other researchers before them have learned through trial and error, and they have used clinical trials to study diseases. In 1774 James Lind followed through with the first clinical trial of the modern era studying scurvy.
The author believes that biomedical research is the way of better understanding medicine and without randomized clinical trials the field of medicine will have insufficient information. He argues that randomized clinical trials are the most scientifically sound and ethically correct means of evaluating new therapies. The belief of a physician being unethical when running randomized clinical trials is rejected by this article because previous trials on patients can have a better outcome on future patients. This article stresses that randomized clinical trials must be carefully designed that has an intended purpose of gathering data to improve the wellbeing of patients. If the patient is to endure a clinical trial he/she must be properly informed of the risks of the trial and the health of the patient should be high priority. Overall this article explains the importance of randomized clinical trials and debunks the idea of randomized clinical trials as being unethical. This article uses a utilitarian point of view and gives reasons why these trials can be in the best interests for both the patient and society.
When penicillin was released to the public in 1944, it was a miracle drug. Infections that had been killers were suddenly treatable. Doctors recommended it generously, both for illnesses that needed it and illnesses that didn’t. Before long, however, it took much stronger doses to see penicillin’s effects. When the antibiotic arms race began in 1944, most physicians assumed that new antibiotics would be discovered or created to keep up with the evolving resistance in bacteria, but the bacteria are constantly evolving new defenses and doctors are starting to run low on antibiotic ammunition. MRSA, methicillin-resistant Staphylococcus aureus, is one of many types of bacteria
The Great Experiment was a period during the 18th century, where job expansion increased so there was less unemployment in the United States. Experimentation occurred from the mid 1700s until 1787. The Great Experiment recognized that individual rights are derived from a Creator. Power was restricted through The Constitution, and it carefully divided, balanced, and separated the powers of the government and organized them through a sytem of checks and balances. The Great Experiment was the exact opposite of the period that occurred in the 1930s, The Great Depression, when jobs were limited and the stock market crashed.
Methicillin resistant Staphylococcus aureus (MRSA) has been a type of multidrug resistant organism and staph bacteria known to cause serious infection that can lead to long hospitalizations and death. It can begin as a simple infection on skin or in the lungs, and if left untreated, can lead to traveling to the bloodstream and causing sepsis (“Methicillin-resistant Staphylococcus aureus (MRSA), 2015”). The Centers for Disease Control and Prevention reports that 33 percent of individuals carry the staph bacteria intranasally and two percent of individuals carry MRSA (“Methicillin-resistant Staphylococcus aureus (MRSA), 2015”). Even though this is a serious issue among healthcare settings all over the country, the number of people affected
Dr. Lindsey N. Shaw, the co-author of the study and USF microbiologist said that in the recent years, MRSA has become resistant to vancomycin and threatens to take away the most valuable treatment option against staph infections.
For example, penicillin, the first antibiotic, was discovered in 1928. Since it was used excessively, bacteria developed resistance to it in 1940, just 12 years later. Then, the chemical nature of penicillin was altered to create methicillin. Now, bacteria have developed resistance to methicillin. MRSA, Methicillin Resistant Staphylococcus aureus, is considered a serious threat by the CDC (Alic par. 2,6,9). MRSA is a huge problem because it is mainly community acquired. Athletes, especially football players and wrestlers, are highly susceptible to MRSA because MRSA is a wound infection that can enter the body via microscopic openings. According to the U.S. Department of Health and Human Services, one-third of the people in the world carry S. aureus in their bodies. This means one-third of the population is at risk of developing MRSA (“Methicillin” par. 1,4). Since bacteria have developed resistance to methicillin, doctors have started prescribing vancomycin, another antibiotic. However, bacteria have developed resistance to vancomycin as well. VRE, or Vancomycin Resistant Enterococci, is the cause of one-third of all ICU (Intensive Care Unit)
If the infected wound is mild and has not infected the internal body, antibiotics may not be needed. The treatment will only include the wound being cut and drained. If the infection is more severe and antibiotics are needed, there are newer types the can be used. MRSA has been shown to respond well to drugs such as vancomycin, ceftaroline, and daptomycin. Rarely, a MRSA infection has been shown to become resistant to vancomycin, and progresses to diseases termed “VRSA.” If this happens, a combination of antibiotics will be used. The treatment plan can be more successful if a material sample is obtained, as the culture can be tested to see which antibiotics it will respond to. The antibiotics course needs to be completed in full, even if symptoms disappear. If the course is not completed and the MRSA bacteria is still in the body, the infection is come back and become resistant to the antibiotics originally used. This is how MRSA becomes more dangerous and less susceptible to more and more antibiotics throughout time. The prognosis of patients infected with MRSA ranges and depends on the severity of the infection. If the infection was mild, patients almost always recover full and obtain 100% of their health back. For infections that advance to deeper infections, for patients that were infected with H-MRSA, or for patients that have other health complications such as diabetes, the prognosis is not as positive. There
It is now accepted worldwide that before a drug is brought into routine use its efficacy, safety, and the balance between two need to be formally demonstrated. The efficacy of new drugs nowadays is almost invariably established with a technique known as ‘randomized controlled trial’.