Factors Affecting Human Development During Phases Of Meiosis And Mitosis

2070 Words Mar 12th, 2015 9 Pages
The process of nondisjunction can occur in human development during phases in meiosis and mitosis. The irregularity results in an abnormal amount of chromosomes in the produced cells and causes alterations in those who are affected. Nondisjunctional consequences can be seen in these five examples of genetic inheritance conditions discussed in this paper: Down syndrome, Patau’s syndrome, Edward’s syndrome, Klinefelter syndrome, and Turner’s syndrome. The Mendelian principles of genetics developed by Gregor Mendel include the patterns of autosomal recessive and autosomal dominant. Autosomal dominant and recessive inheritance patterns can cause disorders such as: Marfan syndrome and Huntington disease from the inheritance of dominant alleles, and cystic fibrosis and sickle-cell disease from recessive alleles. Polygenic and mitochondrial inheritance are forms of Non-Mendelian inheritance patterns. Polygenic inheritance is seen in the inheritance of traits like skin color and height and can cause heart diseases and cancer. In mitochondrial inheritance, also known as maternal inheritance, DNA in the mitochondria is passed down primarily from the mother. This form of inheritance causes some disorders like Leber Hereditary Optic Neuropathy and Kearns-Sayre syndrome may occur. Epigenetic inheritance is an unusual process in which epigenetic tags created by a parent’s experience can be passed on to their offspring.

Nondisjunction occurs in human development and can occur in three…

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