Factors Affecting The Central Nervous System ( Cns )

Cannabis is better known by many people as just a recreational drug but studies show that the chemical compounds in Cannabis to cause the death of cancer cells along with relieve chronic pain and anxiety caused by other cancer treatments. Dennis Hill is a cancer survivor who treated and cured himself using cannabis as a treatment he explains how THC works to kill cancer cells when he states “Very simply, when THC connects to the CB1 or CB2 cannabinoid receptor site on the cancer cell, it causes an increase in ceramide synthesis which drives cell death.” THC when introduced to the cancer cell causes a ceramide synthesis in which ceramide starts to build up causing the Sphingolipid Rheostat to push Cytochrome c out of the mitochondria. Cytochrome

As mentioned above numerous studies have shown the viability of cannabis as a potential cancer treatment. Studies have not only shown how marijuana inhibits tumor growth, cell death, and blocking the development of blood vessels needed by tumors to grow but it also can dramatically improve the quality of life of a cancer

B. The American Association of Cancer Research has found that marijuana can slow down tumor growth in the lungs, breasts, and brain considerably.

Glioblastoma is the most common and aggressive form of malignant brain cancer in adults. On average, 8 of every 100,000 people in the U.S. are diagnosed with glioblastoma every year – representing approximately 2% of all cancers diagnosed [1]. Glioblastoma tumors form when astrocytes, star-shaped cells which support and protect the brain, re-enter the cell cycle and start to rapidly divide. Because the brain is supported by a large network of blood vessels, tumors grow quickly and are difficult to remove surgically. Present treatments for glioblastoma are limited to surgery, radiation therapy, and chemotherapy; however, despite these interventions tumors are likely to regrow. Consequently, typical survival time following glioblastoma diagnosis is less than 2 years.

Dr Jennifer Chan, the head of this tumor research, is an Associate Professor & Neuropathologist in the Department of Pathology & Laboratory Medicine, Oncology, and Clinical Neuroscience in the University of Calgary. Besides her work on education, she is also directing a tumorigenesis research team at the University of Calgary, and a tumor banking program which supports pediatric cancer research. Nonetheless, she is also a member of both the Southern Alberta Cancer Research Institute and the Experimental and Applied Therapeutics Program (ExpAT).

First lets look at what keeps cancer cells alive, then we will come back and examine how the cannabinoids CBD (cannabidiol) and THC (tetrahydrocannabinol) unravels cancers aliveness.

Neurons communicate with one another along a synapse. Neurons are excitable cells that are activated via electrical or chemical signals. Nerve cells are an integral part of the nervous system. Neurons are made up of three distinct parts. The three integral parts of the neuron are the cell body, the dendrites, and the axon. The cell body is the middle portion of the neuron and contains the nucleus. It also contains the organelles such as the endoplasmic reticulum and the mitochondria.

Possible symptoms of a herniated disc include pain that radiates through the back and possible down the arms or legs, depending on the location of the herniation. There can also be noted numbness and weakness of the arms and neck. Some people may not even know that they have a herniated disc because not all cases present with leg or back pain. Other signs and symptoms of a herniated disc may include muscle spasms or deep muscle pain. In extreme cases, a patient may present with weakness in both legs and/or the loss of bladder control and bowel control. This is a serious problem called cauda equine syndrome and requires immediate medical attention.

Malignant gliomas are the most common type of primary brain tumors. As already shown in the Central Brain Tumor Registry of the United States (CBTRUS) report from 1998 – 2002, gliomas account for approximately 80 % of all malignant brain tumors and at least 30 % of all brain and CNS neoplasms (Ostrom et al., 2014). A number of putative risk factors that have been associated with brain tumors have been discussed. However, there is no clear cause for brain and CNS tumors. Less that 1 % are linked to lifestyle or environmental factors (Parkin, Boyd, & Walker, 2011). The only exposure that has been shown to affect glioma risk is ionizing radiation and has been classified as a cause by the International Agency for Research on Cancer (IARC) (Cogliano

Additionally, medical marijuana could also cure cancer, a vigorous disease that kills many people daily. Research shows that THC is the main cannabinoid associated with marijuana and has been recognized to contain a strong anti-cancer effect. Wai Liu, a researcher discovered that there are numerous less known cannabinoids that may decrease the growth of cancer cells in Leukemia. Liu also found out that because the cannabinoids are not psychoactive, a patient could have the anti-cancer benefits without having the high feeling associated with THC (Bekiempis 1). Thus, marijuana does not target all rapidly dividing cells like the way chemotherapy or radiation does – which leads to weight and hair loss. Rather, the marijuana attacks the cancer (Bekiempis 1). Additionally, medical marijuana has many therapeutic uses. For example, research proves that

Marijuana’s main ingredient THC is what gives off that “high feeling.” Cannabinoids are chemicals that are unique to the Cannabis plant itself. Cannabinoids are good at killing cancer cells “because they’re not psychoactive, you can actually have the benefits associated with anticancer technology but not have the feelings of high, which are associated with THC. Some cannabinoids are better at killing cancer cells and others are better at slowing their growth, so combining certain cannabinoids has a heightened effect. Plus, they do not appear to target all rapidly dividing cells the way chemotherapy or radiation does - which leads to side effects, such as hair loss. Rather, they appear to attack just the

Because of the copious amount of medical data on the benefits of Cannabis, its low addiction rate and its lack of negative side effects make Cannabis fit the schedule 2 substance instead of the schedule 1 ranking.The earliest uses for cannabis date back to ancient China. It was used for medical remedies. Currently there is scientific evidence to back up the claim that it can help fight illness, including cancer. This has been hypothesized by many in the scientific community. But not until recently have studies been completed ranging from large-scale case studies to testing on animals. The evidence is becoming increasingly common that cannabis reduces tumors in animals as well as in humans. A study done by Harvard Medical shows that it reduced the tumors. "Cumulatively, these studies indicate that THC has anti-tumorigenic and anti-metastatic effects against lung cancer." This was an experiment that used cannabis to treat cancer in mice. The results were that there was a significant reduction of lung cancer in mice. Harvard Medical concluded that the two anti-tumor properties of cannabis, anti-proliferative and anti-androgenic, have beneficial effects in the cure of lung cancer. When used in treatment, the substance, THC, does not compromise human cells. "THC (5mg/kg body wt.) was administered once daily through intraperitoneal injections for 21 days. The mice were analyzed for tumor growth and lung metastasis. A significant reduction (approximately 50%) in tumor weight and

Still, in the case of the endocannabinoid anandamide, it has been shown to produce its effects on cancerous cell growth via a mechanism utilizing the transient receptor potential vanilloid type-1 (TRPV1) receptors and noncannabinoid, nonvanilloid receptors¹. Furthermore, cannabidiol supposedly inhibits growth of glioma through a completely and independent mechanism in vitro and in vivo. Today, cannabinoids have been effectively used to treat the two most prominent side effects of chemotherapy: nausea and vomiting.

Abstract: The time has come for marijuana to be legalized throughout the United States. Marijuana sales bring in millions of dollars. Medicinal marijuana has been shown to slow down or even sometimes stop the growth of lung cancer cells. In the case of marijuana, the benefits far exceed the risks.

Within the human anatomy, an intricate and complex network of specialised nerve fibres and neurons works in collaboration with the central nervous system and peripheral system, designed to carry out the various actions humans perform every day. The nervous system is also known as the master control unit of the human body, as it operates other major functions such as the circulatory and respiratory systems (Jakab, 2006). It is composed of the central nervous system (CNS) and the peripheral nervous system (PNS). The neurons established within the various sections of the nervous system, is structured with three main parts: a dendrite which is a cluster of branches that operates by receiving information from the