Failures Of The World Is Not An Easy Place

7. A 19-year-old model tripped over an extension cord, causing injury to her epidermis. She is afraid the injury will leave a scar. Based on your knowledge of regeneration, what would you say to this patient? Why? Please incorporate all the steps in tissue regeneration in your answer. Without macrophages, wound healing is delayed. Why?

Describe the series of events that occur in skin, which is healing with the help of a skin graft?

Skin repair is an important physiological process which is essential for homeostasis, restoring barrier function and preventing infection (Martin, 2009; Boateng and Catanzano, 2015). Wound healing is defined as a complex, dynamic and the specific biological process associated with the phenomena of tissue regeneration and growth (Mazumder et al., 2016). Regeneration can be defined as a tissue that significantly damaged either completely or partially removed and tissue's original function and cell types must be functional and structurally restored (Mazumder et al., 2016). The process of healing comprises a cytokine, blood cells, extracellular matrix and growth factor (Joao De Masi et al., 2016). The growth factor is a protein that activates and

Proliferative phase occurs within a few days of injury in which cells that were involved in the battle need to tend to their wounds and the regenerate to restore itself to its formal glory as best as possible. The body’s way of restoring itself is through use of angiogenesis, granulation tissue formation, wound contraction and epithelialization. This combination acts of getting new blood vessels to the damage area, aid in the formation of cells to fill in the area which leads to scar tissue, allow the skin to flexible in the repair process and finally resurface the wound with new epithelial

The first couple of paragraphs include an explanation of what is considered a complex wound and the current available treatments. It is beneficial that the authors include an explanation of what the problem is so that the reader can have a better understanding of why this issue is of concern. The paragraphs then transition towards the types of treatments available for the problem and a description of why the current treatments are not sufficient for restorative care.

“Black people be like, ‘Gimme that fried chicken or Imma shoot’,” said the desperate comedian, who was dressed up as a “gangster” in a poor attempt to disguise his prejudice in the name of humor. Humor similar to the latter further endorses single stories, and because the comedian is popular, he has the power to promote an oversimplified generalization of an entire group of people regardless of their individual differences and make his racism appear tolerable, therefore laying the foundation of the cycle of oppression. The single story that young black men who grow up under the oppression of systematic failure will be violent and subvert authority is created by people with power and is the reason why the cycle of oppression happens as it does.

Wound healing can be defined as the physiology by which the body replaces and restores function to damaged tissues (Tortora and Grabowski, 1996). The emergency response to a burning building by the fire brigade and the other professionals involved in restoring it to full occupancy can be used as an

Harper, Young, and McNaught, (2014) explain the four distinct phases of wound healing that are identified as hemostasis, inflammation, proliferation and tissue remodeling. Hemostasis is the body’s response to prevent exsanguinations; thusly, the cascading response to injury causes constriction of blood vessels but if continued, leads to tissue hypoxia and acidosis. The next stage of healing is inflammation. This stage is a result of cells that inhibit and prevent infection and once the resulting threat of infection is gone, inflammation will subside. Prolonged inflammation can lead to chronic wound formation. The next stage of healing is proliferation which consists of angiogenesis, formation of granulation tissue, collagen deposition, epitheliazation and wound retraction. It is during this stage the extracellular matrix is laid down forming

Wound healing is a very complex process. Wound healing has three phases: the inflammatory phase, the proliferative phase, and the maturational or remodeling phase. These phases might overlap at times (Porth, 2011).

My interest in biological sciences came from a strange source—injury. When I was in elementary school, there was never a time when I wasn’t injured somewhere on my body. Bruises, cuts, and Band-Aids were seemingly never ending. One time when I was riding my bicycle, I managed to trip over a stick and land on my knees, causing a deep abrasion on one of them. Instead of flinching or crying in pain, I intently observed in awe as my body worked to stop the bleeding. I closely examined the progress of cellular regeneration on my body, but I had so many unanswered questions. How does blood turn into scabs? Why do wounds become so sore? How does the body heal itself?

Despite being a renowned mural artist, Misty finds herself in despair and lonely in bustling San Francisco. When she seeks comfort in Curt, the one person she trusts, the veil of grief starts to lift.

Wound healing is a sophisticated dynamic process that leads to tissue repair or regeneration and has three main time dependent phases: inflammatory phase, proliferative phase and remodeling phase (1). The healing process starts immediately after skin injury and takes months to complete. During the inflammatory phase, many cytokine mediators are activated by platelet degradation, a process that ultimately leads to recruitment of inflammatory cells, epithelial cells, and fibroblasts. Platelet degranulation leads to activation of clotting cascade to form a hemostatic fibrin clot (1, 2). In the second stage of wound healing, proliferation begins around day 4 or 5 with the relocation of fibroblasts into the wound matrix and inward

In the novel, Why Nations Fail, the authors Daron Acemoglu and James A. Robinson attempt to provide an alternative explanation to the economic disparities seen in the modern world. The authors argue throughout the book that political and economic institutions are the most important cause for differences in economic performances across nations. Developed countries like the United States and Great Britain took important steps in their history to move towards inclusive institutions, while nations like the Congo and North Korea continue to maintain extractive institutions. In order to support their argument, the authors cite numerous examples throughout history that demonstrate how the adoption of inclusive institutions created a virtuous cycle in developed nations, resulting in long-term prosperity. Nations with extractive institutions, however remain in a vicious cycle that inhibit their ability to prosper economically. Acemoglu and Robinson make many compelling points throughout the novel to support their claims regarding the importance of institutions by properly explaining the difference between inclusive and extractive, their importance for sustained economic growth, and using Great Britain as an example to cite institutions historical importance. The authors, however could have strengthened their arguments by addressing the difficulties in implementing institutions that are not suitable for the economic and political environments of certain nations. and the potential for

In Why Nations Fail, Daron Acemoglu and James Robinson show that economic development is about more than just economics. Through a wide variety of natural experiments ranging from Latin America, to Sub Saharan Africa, to East Asia, they argue that it is institutions, both political and economic, that differentiate a country’s economic success. Specifically, they separate institutions into inclusive and extractive. Inclusive political institutions engage the entire population, while extractive political institutions are ruled by an elite minority. Similarly, inclusive economic institutions promote property rights and competitive markets, while extractive economic institutions create monopolies and funnel wealth to the elite minority. The novel part of their thesis is the idea in order to have sustainable inclusive economic institutions, a country must first have inclusive political institutions. It is only when a country has inclusive economic and political

Why Nations Fail takes an in depth look into why some countries flourish and become rich powerful nations while other countries are left in or reduced to poverty. Throughout this book review I will discuss major arguments and theories used by the authors and how they directly impact international development, keeping in mind that nations are only as strong as their political and economical systems.