Fatty Acid Composition Of Adipose Tissue And Colorectal Cancer : A Case Control Study

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Fatty acid composition of adipose tissue and colorectal cancer: a case-control study
Colorectal cancer is considered as the third most common cancers worldwide that usually leads to the death of the patient. Studies have proved that lifestyle factors great influence the development and spread of cancer. Modifying the lifestyle can reduce the risk of getting colorectal cancer by 70%. It is noted that more consumption of red and processed meat increase the risk of developing colorectal cancer. However, high intake of dietary fibers decreases it. On the contrary epidemiologic studies that connect the fat intake with colorectal cancer are varying and unreliable. The concentrations of fatty acids in human serum and in the membranes of red blood cells depict the intake of previous days or weeks. Conversely, the fatty acid concentration in the adipose tissue truly show the habitual dietary intake in the previous two to three years. Hence, various studies that aim to explore the correlation between the concentration of fatty acids and cancer risk use adipose tissue in this request.
The case study discussed in this paper is conducted in Five University hospitals located in Northeastern France (Cottet and others 2015). Subcutaneous adipose tissue samples were acquired from the surgery departments through surgeons. The samples belonged to the patients who were admitted for elective abdominal surgery. These patients were recently diagnosed of primary colorectal cancer.

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