Fecal Microbial Bacteria

662 WordsFeb 17, 20183 Pages
According to the Centers for Disease Control and Prevention; most healthcare-associated infections (HAIs) such as staph or MERSA are dropping except for one: Clostridium difficile infections or CDI which causes an estimated 14,000 diarrhea related deaths in America each year. Clostridium difficile is a gram positive, anaerobic bacteria that can produce exotoxins, form spores and is beginning to show increased resistance to antimicrobial treatment. Symptoms of CDI include watery diarrhea, fever, loss of appetite, nausea and abdominal tenderness (CDC 2011). The usual treatment for CDI is first to cease use of any antibiotics that first may have caused the CDI. If symptoms do not improve, then a stronger course of antibiotics is usually done but CDI has a high rate of reoccurrence. In a double-blind, randomized trial comparing the efficacy of fidaxomicin vs. vancomycin in treating CDI the reoccurrence rate was 15.4% for fidaxomicin and 25.3 for% for vancomycin (Louie et al. 2011). There is, however, a solution with a cure rate upwards of 90% with no chance of increasing antimicrobial resistance; the fecal microbial transplant (FMT). A fecal microbial transplant involves taking a fresh stool sample from donors screened for transmissible disease and parasite infection, diluting it with sterile saline or milk and administering via nasoduodenal tube or enema (van Nood et al. 20013). The donor may be any healthy, medically screened adult, either an unrelated stranger or a family
Open Document