Fetal Tissue Research On The Rebound

The purpose of this study was to see whether implanted embryonic dopamine neurons in Parkinson's disease patients led to a relieve of symptoms and also to see whether age played a role in whether the implanted neurons survived. All the participants were patients with Parkinson's disease who had if for at least seven years and had all three signs of Parkinson's disease. The patients were placed in groups of ten, some were given sham surgery and others transplantation. This was a double blind study. What was found was that patients who were 60 or younger actually responded better to the treatment and of the 40 patients only 39 actually completed the study, one of the patients died in a car crash before the study was finished the study lasted for a whole year. Also only patients who were 60 or younger reported positive feedback like showing actual improvement. The other patients were actually showing negative results which is not good because that meant that the disease was actually getting worse. The scores of one of the tests used showed some differences between the sham group and transplant group when not

Many young children are vaccinated every day, but do you know what is in vaccines? Almost all vaccines have one ingredient in common: cells from aborted baby fetuses. The medical community needs to realize it is not appropriate to use fetus cells in vaccines for many reasons.

“Genetic engineering and drug development can cure and therapies of Parkinson’s disease and Alzheimer’s disease, so embryonic stem cells in not the only way to treat patients” (McLean 3). People witness the development of cancer treatments with the enhancement of more effective drugs. Also, nanotechnology allows scientists to deliver drugs only to the cancerous cells, so that the nearby healthy cells remain unaffected. Genetic engineering provides prospect in curing Parkinson’s disease which causes loss of body control. “Scientists develop Parkinson’s disease in laboratory mice to and genetically engineer their nerve cells to make them become light sensitive. When these nerve cells are exposed to light, then nerve impulses travel along them and the mice are again able to move their bodies” (McLean 4). People speculate that this discovery can be used to cure Parkinson’s in humans. Critics of embryonic stem cell research believe that people don’t need to pursuing embryonic stem cell research will be negated by promising advances in drug development and genetic

And there this field is always developing new techniques to slow or stop the progression of this aggressive degenerative process. It is now under investigation the use of gene therapy combined with surgical approaches. It was pointed out by Kang, Papasian, Chang, and Lee (2003) the exact mechanisms of the degeneration that takes place in Parkinson's may not be well understood, especially the main cause that unleashed the neuronal alteration, however to prevent the progression it is important to understand the general process of cellular death (p.339). At this point of the disease the patient is already being treated by a multidisciplinary patient, and now more than ever it is key for the clinician to keep by the patient's side guiding him through the rough path, being a light and a support for him and for his family. Don't let the person feel overwhelmed by the weight of being sick. Always keep in mind the holistic approach of the patient and giving support in all the aspects of his life, only this way we could give relief and peace of

Disease risks are uprising and are showing differences in specific sexes. Most clinical trials have a majority of female participants. A clinical trail done in March 2007 and May 2010 of early treated Parkinson’s disease severity; scientist gathered and compared research from male and female candidates. The research contained collected data information of the age at which one was diagnosed, symptoms at diagnosis, and

“The power of placebos has been recognised for improving numerous medical conditions”(Fernandez 2001). However, there is still much speculation as to how the underlying mechanisms of an inert substance manage to instantiate that improvement. To better understand the role of placebos in treatment, a 2001 study of the placebo effect on Parkinson’s disease was conducted.

Parkinson’s disease is common throughout society, but the exact cause of the onset of the disease is unknown (Damjanov, 2012). Although the incidence rate for people over the age of sixty is one out of every one hundred people, the number of people who are actually affected may be higher due to the lack of an exact test to diagnosis Parkinson’s disease (The Michael J. Fox Foundation, n.d.). Parkinson’s disease is progressive and results in the continuous degeneration of the central nervous system (Damjanov, 2012).

The aim of this research is to determine if stem cells can be used to cure Parkinson’s disease. I too aim to determine if such may be achieved by using stem cells that are obtained in an ethically unchallenging manner, such as by using induced pluripotent stem cells, which are created from one’s own skin, to cure the disease.

This paper will discuss Parkinson’s disease the cause, signs and symptoms, early detection, common associated effects, treatment, solutions to environmental and genetic effects, and illness prevention strategies. While covering all these topics we will discuss how important it is to know about this disease and how we can better treat this disease to help our loved ones when they are diagnosed with Parkinson’s disease.

Clinical trials were very limited early on in both size and number, but researchers were able to see how stem cells would be able to help with neurodegenerative diseases (Gibson et al, 2012). In 1995 Kordower and colleagues started their trials; 18 months later the grafts survived and remained intact and the patient registered improvement in the Unified Parkinson’s Disease Rating Scale (UPDRS) test (Gibson et al, 2012). Fetal brain tissue (stem cells) was used to create grafts into the areas of the brain affected by Parkinson’s disease. Some of these people were markedly improved, and the effects lasted for 18 months, and in some cases over 10 years (Gibson et al, 2012). An effect of Parkinson’s disease is the destruction of brain cells. With stem cell treatment there is hope that with healthy and functioning brain cells the disease can be reversed (Murnaghan, 2013). Due to that success more testing was warranted in both size and

About 10 million people in the world are affected by parkinson's. Parkinson's is caused by a depletion of dopamine producing neurons in the brain. The only current treatments are medicine and electrical implants in the brain and cause severe effects after time and fail to present disease progression. There have been studies that show embryonic stem cells improve motor function in studies done on animals. But until recently this procedure has shown to be unsafe and risky, because the risk of tumors. In the new studies researchers used mice modeled to parkinson's and were separated into 3 groups. The first group didn't get the stem cell implant, the second group did receive a stem cell implant but they were not treated with mitomycin C. Finally

Parkinson’s disease is a disease with a wide variety of disabilities recognizable as changes in appearance, posture, walking, and balance. In 1817, the English physician James Parkinson described these symptoms in his patients and has had his name become synonymous with the disease. In 1893 the substantia nigra of the basal ganglia was identified as an area of disease for Parkinson’s. Examination with the naked eye reveals a lack of black pigment in this portion of the brainstem. Subsequent follow up with the microscope showed a deterioration of the nerve cells in this area. The circuitous relationship between the substantia nigra and the basal ganglia explains many of the symptoms of Parkinson’s disease. Today the

“Stem cells can be used to heal the damage in the brain caused by Parkinson’s disease.” According to scientists in Sweden. They sad that their study on rats helped develop effective treatments for it. There is no known cure for the disease, but medicine and brain stimulation can help relieve symptoms. The disease is caused by the loss of nerve cells in the brain that make dopamine. To stimulate Parkinson’s disease, Lund University researchers killed dopamine producing neurons on one side of the rat’s brain. Then, they converted human embryonic stem cells into neurons that produce dopamine. This was injected into the rat’s brain, and researchers found signs that the damage was reversed. They said “… no human clinical traits of stem-cell-derived

In this systematic review, it was looking at if physical therapy helps people with Parkinson’s disease compared to no intervention or with placebo (Tomlinson, Patel, Meek, Herd, Clark, Stowe,…& Ives, 2012). At the end of the studies, they found that there was four outcomes that showed a slight improvement which were the following: timed up and go, gait speed, questions on freezing of gain, and 2 or 6 minute walk. However, Berg balance scale, functional reach test, and activities of daily living and subscores showed great improvement. They also measured the quality of life, but it showed no improvement, but no decrease. The conclusion that was made when summing up all the studies was that physical therapy can help improve people in their

Parkinson’s disease (PD) is the second most common neurodegenerative disorder that affects over 1 million individuals in the US, and unfortunately, about 50,000 new cases are diagnosed yearly (Tarazi et al., 2014). Looking through different emerging treatments, I came across many, including pharmacotherapies, as well as surgical, and non-surgical procedures. While I believe many of these emerging treatments (such as viral vector gene therapy or stem cell therapy) are far from being approved in the US due to their invasive procedures or insufficient research, I however came across an emerging treatment that I presume will soon be approved in the US as opposed to many other ones. Therefore, in this research paper, I will discuss the emerging