Finding a Cure through Regenerative Medicine: Government-Funded Embryonic Stem Cell Research

Imagine a world free from disease. The idea of a utopian society has been far from reality until the research from embryonic stem cell therapy surfaced. Since former president George W. Bush banned federal funding on embryonic stem cell research in 2001 it has caused a halt in advancements and caused controversy in the public. According to an article by Beau Watts, an accredited physician; embryonic stem cells are pluripotent cells (Beau Watts). This means they have not decided what function they perform yet. Since the cells do not know the function, it can be determined by scientists. As described in the “Guidelines for the conduct of human embryonic research” by the international stem cell society; medical professionals can take an embryonic stem cell and “reprogram” it to eliminate the disease. Today 2,200 people died from heart disease (American heart association). Heart disease is only one of many diseases that can be cured by embryonic stem cell research. Religious and/or conservative groups now condemn the research, for multiple reasons. Embryonic stem cells are donated by patients of in-vitro fertilization. After a “round” of IVF, they can choose to donate, freeze, or discard their leftover embryos. Embryos contain two layers, it is the innermost layer that contains the cells used in embryonic stem cell research (Society for stem cell research). It is very important to know that, the embryos that could be used in the research are donated upon request of the patient.

These cells come from fetuses which is why stem cells are such a controversial issue. In order to actually use embryonic cells, they must be harvested from an unborn baby that is in the early stages of life. Embryonic cells have the ability to be all 220 types of tissues in the human body. “This makes them ideal for regenerating diseased heart tissue, repairing spinal cords, and replenishing brain cells”, Elizabeth Svoboda, an author in the publicized Popular Science magazine, illustrates in her article about stem cells (60). Embryonic cells have limitless possibilities in medical advancement. These cells can become whatever type of cell a doctor program them to be. With the use of embryonic stem cells, doctors can cure several diseases, as well as curing people who have suffered injuries, but research is being slowed down by the ethical dilemma of aborting a

It has the ability to form any type of specific cell and thus has the greatest potential for treatments in the near future.  A more recent development in stem cell research is the creation of induced pluripotent cells, which are adult cells that become undifferentiated through a series of treatments.  Induced pluripotent stem cells have a number of benefits because the destruction of embryos is not necessary and there are no issues with immune response or rejection because the cells come from the patient.  However, it will be a long time before this type of cell become widely used on humans because the method used is not completely understood and has negative side effects.  In animal testing, “…the virus used to introduce the stem cell factors sometimes causes cancers” (“Stem cell basics”).  Therefore, embryonic stem cells should be an important part of stem cell research.  Even if induced pluripotent cells can replace embryonic cells in the future, the knowledge gained from current embryonic cell research would still be very applicable.   Unfortunately, research is very time and resource intensive, which is where the debate of federal funding comes into play.

The embryonic stem cells can be used for various medical cure. It can help treat diseases including Parkinson's, stroke, heart disease and diabetes. The embryonic stem cells are cells that can easily be transformed into any cell. This can help treat many diseases but this may also increase the number of women selling their eggs and undergo dangerous procedure to do. We don’t agree with the use of the embryonic stem cells for research.

Upon review of the legislative interpretation put forth by Harriet Rabb, new President Bush announced on August 9, 2001 that federal funding would be restricted “only to the human stem cell lines existing as of [that date] (then estimated at about [21] lines) and officially withdrew President Clinton’s guidelines a few months later” (Kearl 1). In this decision President Bush had decided that federal funds could be used “for research on the existing stem cell lines, where the life and death decision has already been made” (“President Discusses Stem Cell Research”). This is where the Clinton administration’s guidelines differed. They did not specify between currently existing and not yet existing human embryonic stem cell lines. Both guidelines did agree, however, that the federal government should not fund human embryonic stem cell research that directly destroyed embryos. In response to President Bush’s decision over 200 members of Congress signed a letter in

The Department of Health and Human Services maintained a moratorium on federal funding for research on embryos and fetuses, as well as in vitro fertilization, until President Clinton issued an executive order lifting it in 1993 (Scott p.153). However, Congress banned federal funding for human embryo research by adding legislation known as the Dickey-Wicker Amendment to every appropriations bill for the National Institutes of Health since 1995, making it impossible for the President to overturn the ban without also cutting the cash flow to the NIH (Scott p.154). This restriction remains in place today. On August 9, 2001, President Bush “clarifies which human embryonic stem cells can be used under federal funding rules” by stating that any lines derived from excess IVF blastocysts before his announcement are eligible for grants (Hopkins 2005). Then in 2009, President Obama lifted the 'made-before ' restriction for stem cell lines but maintained the ban on creation and destruction of embryos for research purposes (Madison.com 2009).

"Embryonic stem cells are special because they are the only cells that can make all parts of the body,” said Douglas Melton, in an interactive videoconference available at athome.harvard.edu. The conference was hosted in New York and broadcasted to Cambridge, Washington D.C., and Naples, Florida on March 2, 2004. "Embryonic stem cells can do everything. So if you want to work on replenishing tissues, that’s where you go."

Embryonic stem cells have numerous and amazing uses. Stem cells are unspecialized cells with the ability to replicate and renew themselves. They have the ability to transform into many kinds of cell types within the human body. They divide and create a new cell, having the potential to infinitely replenish cells. There are two types of stem cells: embryonic and somatic. Embryonic stem cells are from a fetus and can become all cell types in the body. Somatic stem cells are from an adult and can become only certain things due to the origin of the cells. Scientifically

Millions of people die every year from diseases, accidents, and defects, one only needs to turn on the nightly news to hear of the devastating effects of cancer or of horrific accidents that have left people disfigured or paralyzed. Stem cell research is a part of biomedical science that has the potential to cure diseases and defects, create organs for patients needing transplants, regenerate axons in spinal cord injuries, and create new treatments, drugs, and immunizations. However, federal funding is limited and does not cover embryonic stem cell research to an extent that would make a difference in medicine. The United States should support embryonic stem cell research by increasing federal funding, opening new stem cell lines for

Parkinson’s disease is a very well-known disease. It plagues about five million people worldwide, about a million of those cases are in the United States. A person does not lower their chances of getting Parkinson’s by living in a certain part of the world. It is not more, likely to happen in one location than, another. It has to do with age and genetics (“Demographics of parkinson’s,” 2014). It is a disease of the older generation, around about one percent of people over the age of 60 years old have Parkinson’s disease (Hauser, 2014). As one ages the likelihood of a person developing goes up. About four percent of people over the age of 80 years old develop Parkinson’s disease. The percentage of people who have Parkinson’s that are younger than 40 years old, is less than 10 percent. It is more

Unfortunately, embryonic stem cell research involves extracting stem cells from embryos, thus killing them in the process. According to Stanford.edu, “Opponents of HESC [Human Embryonic Stem Cell] research argue that the research is morally impermissible because it involves the unjust killing of innocent human beings.” Yes, these embryos are dying from the extraction of their stem cells, but the fact of whether or not this is killing innocent human beings solely depends on point of view. If you consider a five-day old embryo to be a human being, then perhaps you would consider this to be wrong, but you believe otherwise, then maybe you would agree with the sacrificing of these embryos for beneficial research. This is how embryonic stem cell research has been very controversial in prior years and even

Stem cells are grown on Petri dishes in a laboratory and are never implanted in a woman’s uterus. These cells can be used to create stem cell lines that can grow indefinitely under optimal conditions (“Stem cells and diseases,” 2011). Embryonic stem cells can be obtained from existing stem cell lines (any group of cells that came from the same original embryo), aborted or miscarried embryos, unused in vitro fertilized embryos, and cloned embryos created from somatic cell nuclear transfer (the nucleus from an unfertilized egg is removed and replaced with a nucleus from an adult stem cell). This technique would be used for therapeutic cloning, which could grow organs or skin grafts for patients. However, the only research that is federally funded are a few embryonic stem cell lines created from unused embryos at in vitro fertilization (IVF) clinics before 2001 (Dunn, 2005; “Embryonic & fetal research laws,” 2008; Therapeutic cloning, 2009). These lines are not enough to allow scientists to fully explore and take advantage of potential findings.

First of all an understanding of what a stem cell is, where it comes from, and the significance of it's medical potential is essential. Stem cells are the "master cells" that form the human body or whatever other animal it is from. Stem cells can be extracted from adult tissues, bone marrow, umbilical cord blood ( ), and embryos in the blastocyst stage. Although scientists have found ways to manipulate the stem cells from adult sources into other types of cells, they claim that they are less capable of deriving the desired tissue and are not "biologically equivalent" ( ) to stem cells extracted from embryos.

Once the stem cells are derived from either the In Vitro Fertilization embryo, or the aborted fetus they are then put into a cell culture where they can grow. If the cells stay alive during this time period they are sent to other laboratories for research.

The controversial topic of stem cell research has been a controversial topic for a very long time. In 2001, George Bush severely restricted government-funded stem cell research. In 2009, Barack Obama allowed it. The order says that National Institutes of health can produce new procedures and policies in which the money can be used. On August 23, 2010, a federal judge issued an order blocking all research of stem-cells, including that allowed even when Bush was president. On July 27, 2011, Royce Lamberth, Chief judge of the federal court in Washington, D.C., said that stem cells could be used for life-threatening diseases. The Court of Appeals agreed with this, and the case was brought to a close (Stem cell policy).