Fosamax Case Statement

During the first few days you may experience very mild body discomfort, such as very light diarrhea, joint pain, and very mild upset stomach, which are normal and natural detoxifying process as your body is

Denosumab is a biological product used in the treatment of osteoporosis which is the condition of fragility in bones which have lost tissue due to lack of vitamin D or inadequate calcium. This product is the first RANK inhibitor meaning it prohibited the activity of the protein. (Calkins 2017)The prohibiting of RANK minimizes the failure of bones. Denosumab is given out by a health care professional who injects a dosage of 60mg after every six months. (Green 2010)

Before starting pharmacological medication preventive measures should be taken. For example, weight-bearing exercise, calcium and vitamin D intake, quit smoking and alcohol. After that start osteoporosis medication if it is primary, but if it is secondary treat the underlying cause first. These drugs do not treat osteoporosis, but decrease further loss of BMD which include Bisphosphonates (Alendronate- Risedronate- Ibandronate- Zoledronic acid), Raloxifene (Selective estrogen receptor modulators), Calcitonin (hormone decreases bone resorption by inhibiting osteoclast activity), Denosumab, Teriparatid(Parathyroid hormone). The first drug used is alendronate because of its high efficacy in preventing fractures and low cost. If the first line drug failed other bisphosnates or denosumab can be used. Ralaxofeine used as third line drug because it has a risk of developing blood clot diseases, yet it decreases the risk of breast cancer . Calcitonin is used for those who are contraindicated to the previous drugs because of its low efficacy. Teriparatid is the only drug that works by increasing BMD, but is the last drug used. It is taken for a maximum 2 years and expensive and contraindicated in those who have history or having a bone cancer. For those patients who complain of sever back pain surgery might be suitable for them as a last solution although the efficacy and safety

Possible side effects: “dry mouth, sedation, blurred vision (disturbance of accommodation, increased intra-ocular pressure), constipation, nausea, difficulty with micturition; cardiovascular side-effects (such as ECG changes, arrhythmias, postural hypotension, tachycardia, syncope, particularly with high doses); sweating, tremor, rashes and hypersensitivity reactions (including urticaria, photosensitivity), behavioural disturbances (particularly children), hypomania or mania, confusion or delirium (particularly elderly), headache, interference with sexual function, blood sugar changes; increased appetite and weight gain (occasionally weight loss); endocrine side-effects such as testicular enlargement, gynaecomastia, galactorrhoea; also convulsions (see also Cautions), movement disorders and dyskinesias, dysarthria, paraesthesia, taste disturbances, tinnitus, fever, agranulocytosis, leucopenia, eosinophilia, purpura, thrombocytopenia, hyponatraemia

Some of the immediate physical complaints include constantly feeling cold, bloodshot eyes with dark circles, finger calluses, dizziness, weakness, lackluster hair, moodiness, insomnia, no menstruation, swollen glands, weight loss, sore throat, or dry skin. Some of the long-term effects include extreme weight loss, gastrointestinal pain, diarrhea and/or constipation, malnutrition, loss of tooth enamel,

Some of the side effects are: Loss of appetite, Nausea and vomiting, weakness and fatigue, weight gain, premature menopause and hair loss.

Short-term effects are increased respiration, rapid heart rate, decreased appetite, increased physical activity, irregular heartbeat, increased body temperature, and increased blood pressure (www.drugabuse.gov). The long-term effects include: skin sores, extreme weight loss, and severe dental problems, as well as higher risk of contracting infectious diseases (www.drugabuse.gov).

The report has been divided into three parts; part-1 discusses the lawsuit in detail; part-II describes company involved in the laws suit and Part-III discusses the business impact of the lawsuit. The author has tried to cover all the aspects of the issue. Part-I discusses the actual allegations, background of the allegations, key players and the relief sought. In part-II I have described background of GlaxoSmithKline, its history, products,

Fosamax is a biphosphonate that is commonly used for the prevention and treatment of osteoporosis. It would be best to take Fosamax on an empty stomach with plenty of water. Do not lie down or eat for at least 30 minutes after taking the pill. The side effects for Fosamax are abdominal pain, bone/skeletal pain, constipation, diarrhea, dyspepsia, and nausea. I would also tell M.S that osteonecrosis of the jaw may occur after dental extraction, root canal, dental implant or other oral surgeries. Lastly I would tell M.S. that oral biphosphonates are commonly associated with a serious problem called esophagitis which is inflammation of the esophagus. If chest discomfort occurs which is a symptom of esophageal irritation, she should discontinue the drug and contact her health care provider. I would assess her for poor renal function, hypocalcemia, and GERD because if she has any of these, she would not be able to take Fosamax.

Adverse reactions to this medication are migraine, speech disorders, rhinitis, sinusitis, hyperglycemia, elevated liver function, elevated serum creatinine level, pancytopenia, bronchitis, dyspnea, toxic epidermal necrolysis, anaphylaxis, elevated creatine kinase, generalized pain, and infection. Nursing considerations with this medication is to have the patient swallow the whole tablet and not to chew. Watch for aspiration while watching the patient take the medication. Educate the patient about the medication and inform them to notify a physician if bleeding

As with any medication out there, 5-FU has side effects that may or may not subside. According to MedlinePlus, some of the common symptoms include: loss of appetite, unusual fatigue, dizziness, headache, hair loss, dry and cracked skin, vision changes, sensitivity to light, redness, pain, swelling or burning at the injection sight and confusion. However, some more serious side effects are sores in the mouth and or throat, diarrhea, vomiting, fever, chills, nosebleeds, and chest pains (Fluorouracil Injection: MedlinePlus Drug Information). Any side effect that interferes with the quality of life of the patient should be mentioned to the doctor immediately, to assess whether the current treatment is appropriate and if the medication has been

Safety: I will call HA in 24 hours to assess if HA is experiencing any adverse effects from famotidine therapy for GERD symptoms. If he experiences adverse effects of famotidine such as diarrhea, constipation, headache or dizziness, HA is directed to seek his physician or pharmacist. If HA experiences serious adverse effects such as Steven Johnson Syndrome or seizure or an allergic

Alendronate sodium is often used in osteoporosis. Alendronate and cholecalciferol may also be used to increase bone mass in men who have osteoporosis. Unusual weight loss is side effect of this drug. Many people who are taking alendronate suffering from the weight gain/loss as a side effect. And in several clinical studies of this drug, it is reported that weight gain/loss is because of the drugs side effect. I would suggest you to speak with your doctor about the same. Doctor may prescribe you alternate medicine based on your medical

In case you observe some complications, don’t be late to consult a doctor. As mentioned earlier, that the side effects are rare and mild. Visiting a doctor will exempt you from pain and suffering.

nausea, limb pain and hair loss. Flushing and gastrointestinal problems are the most common side effects of dimethyl fumarate.