G6d Research Paper

Fatigue: The growth and development of red blood cells in the bone marrow may be suppressed while having increase in the number of malignant plasma cells, which then cause low levels of red blood cells in the blood. This condition, know as anemia, can result in unusual fatigue or weakness.

Anemia is a disorder of the blood. It occurs when your body does not produce enough erythrocytes or red blood cells (RBCs). Without the erythrocytes oxygen can not be adequately delivered to the tissues and organs throughout the body. This will cause you to become weak and tired. A person may also experience headaches, skin pallor, and faintness. Your body may attempt to compensate for these symptoms by speeding up the heart rate and respiratory rate. This is the body’s attempt to return oxygen levels to normal(Thibodeau and Patton, 2005).

1. Which of the following anemias is caused by a failure of the bone marrow to produce red blood cells and may be congenital or acquired?

Otherwise known as G6PD deficiency, people with an extreme case of this illness would experience hemolytic anemia, fever, and fatigue after eating fava beans or take drugs like primaquine. This is due to the fact that people with favism lack sufficient amount of the enzyme G6PD, which is important for protecting cells from chemical elements that would otherwise destroy the cells. The substances mentioned above act as the catalysts for the production of free radicals (un-paired electrons). As these un-paired electrons seek to pair with electrons in red blood cells with deficient amount of G6PD, it causes the cell membranes to burst. The loss of red blood cells when left untreated can cause the person to have kidney failure, heart failure, and death. As of now, there is no treatment for G6PG

This anemia results in fatigue and a number of the following problems;pain episodes, strokes, susceptibility to bacterial infections, particularly in children, leg ulcers, bone damage, yellow eyes or jaundice, early gallstones, lung blockage, increased infections, kidney damage and loss of body water in urine, painful erections in men, blood blockage in the spleen or liver, eye damage, low red blood cell counts (anemia), and delayed growth.

The events that took place during G.O. weekend were fun, informative, and beneficial. The events that were most impactful for me were the faculty and department meetings and the informational skits. The faculty and departmental meetings stood out to me because it was very exciting to meet the faces of your major’s department before the first day of classes. The informational skits were impactful because it displayed real, scary issues that take place frequently on college campuses across the nation and provided ways to handle these situations.

Limiting certain substances in the diet can help prevent the buildup of potentially toxic substances that are normally broken down by the enzyme. In some cases, enzyme replacement therapy can help compensate for the enzyme shortage. These treatments are used to manage existing signs and symptoms and may help prevent future complications. For other genetic conditions, treatment and management strategies are designed to improve particular signs and symptoms associated with the disorder. These approaches vary by disorder and are specific to an individual's health needs. For example, a genetic disorder associated with a heart defect might be treated with surgery to repair the defect or with a heart transplant. Conditions that are characterized by defective blood cell formation, such as sickle cell disease can sometimes be treated with a bone marrow transplant. Bone marrow transplantation can allow the formation of normal blood cells and if done early in life, may help prevent episodes of pain and other future complications, according to the United States National Library of Medicine (NIH

Also known as normocytic anemia. This is the most frequent type of anemia most often happening to males over 85 years old. It is a common problem that occurs to men and women over 85 years old. Symptoms include and are caused by: a reduced production of normal-sized red blood cells even though presence of hemoglobin in the red blood cells is within the standard range; an increased production of HbS as is seen in sickle cell diseases; greater destruction and loss of red blood cells; an increase in plasma volume that is not compensated by anything else; a B2 (riboflavin) deficiency; and a B6 (pyridoxine) deficiency. (Brill & Baumgardner 2000).

Blood transfusions are another option. This can increase the number of red blood cells that cause anemia and makes the body weak and it can fight off other complications from the disease. Gene therapy is a newer treatment that inserts a normal gene into the bone marrow of a person with sickle cell anemia hoping for a result of normal hemoglobin but this process is still in an experimental stage.

My son Jimmy is now 10 months old. Just recently I’ve found out that he has G6PD deficiency. When my wife found out she was a bit frightened, but after we talked it over with the doctor she found out it wasn’t that bad. Only in severe cases it can lead to kidney failure or even death. It can also cause anemia. Hemolytic anemia is something you would want to avoid.

who suffer from GBS recover completely and the remainder are left with varying degrees of weakness and

This is rule of our body. But there is time for apart and dying these red blood cells. Red blood cells live almost one hundred twenty days in body. So, it is necessary to be replaced before this time. But on the other hand, sickle cell dies almost within ten to twenty days. This is no enough time for red blood cells for replace one to another place. When red blood cells are living for very short time. than its called disease of anemia If there will be lack of red blood cells than body cannot gain proper oxygen. Than body don’t feel energized. Our body feel lazy and don’t want to do any work because body always feel

Glucose-6-phosphate dehydrogenase deficiency was discussed in the book and I wanted to research more about the prognosis and treatment. The deficiency is caused by a mutation in the G6PD gene. This disease is inherited from the X chromosome and passed on either from one or both parents. The enzyme, Glucose-6-phosphate dehydrogenase, is produced by the gene and is one of the many enzymes that takes part in the breakdown of carbohydrate. However, it is also known for its protective role in red blood cells against reactive oxygen species. The enzyme prevents the accumulation of reactive oxygen species within the red blood cells. Therefore, the mutation of the G6PD gene causes either a decrease in concentration or structural modification of the

For children suffering from autoimmune hemolytic anemia, therapy and treatment will be based upon the child’s age, the general health of the child, and the child’s medical record. Treatment will also depend on the extent of the anemia, the cause of the anemia, and the child's tolerance for certain medications, and potential course of the anemia. The treatment for children with autoimmune hemolytic anemia may consist of blood transfusions, corticosteroid medications, and possible surgical removal of the spleen, for children who do not respond to other treatments.

Glucose-6-phosphate dehydrogenase (G6PD) Deficiency is a genetic disease that cause insufficient of G6PD in the blood. G6PD is a vital enzyme that keeps red blood cells (RBCs) function properly in our body. Lacking of G6PD will cause RBCs break down faster than body can replace them when body is getting certain medicine or infections or other factors.