preview

Gaining Control of the Gene Responsible for Apoptosis Essay examples

Decent Essays
Gaining Control of the Gene Responsible for Apoptosis When we gain control of the gene responsible for the phenomenon of apoptosis, we will be in control of aging. We are finding more evidence every day, indicating genetic links to all sorts of factors in the human being. We are just now beginning to scratch the surface of our own genetics. A landmark discover has just been unveiled: In February [2001], the two groups charting the human genome published their results—the entire 3 billion base pair sequence. The only definitive conclusion so far: Humans are far more complicated than we thought. …Eric Lander, director of the Whitehead Center for Genome Research in Cambridge, Massachusetts … adds: “within a decade, we will understand…show more content…
Once this model of bone is complete, the cartilage cells are given the command to die. Osteoblasts, or bone building cells, move in to the space formerly occupied by the Condrocytes, and replace the cartilage matrix with a Calcium rich, rock hard, matrix, we know as bone (188). In the foregoing example there are instances of cells being told to die, this is programmed death, and known as apoptosis. During life, our cells carry out metabolic functions, producing digestive enzymes and waste products, which are harmful to surrounding cells, if it spewed into the fluids among the cells. These enzymes and toxins must be packaged in a way that is not harmful to the interstitial environment, and in a manner in which appropriate cells in the region can readily absorb them. This must be done without invoking an inflammatory response (Browder).

Aging, also known as Senescence, is a natural process, “beginning at reproductive fitness and culminating in death,” Observed in most living organisms, senescence is characterized by a gradual reduction in “reserve capacity of organ systems”, (Heydari). Supporting research by U. of Florida’s Aging Biochemistry Laboratory indicates an increased apoptotic rate of cardiomyocytes, T-lymphocytes, and neurons, as age advances (Leeuwenburgh, par. 3.1). These factors manifest the classic signs of aging as well as many age-associated diseases, such as reduced cardiac function, susceptibility to illness and
Get Access